Articoli con mandati relativi all'accesso pubblico - Theo KleinUlteriori informazioni
Non disponibili pubblicamente: 3
Proteolytic Cleavage Mechanisms, Function, and “Omic” Approaches for a Near-Ubiquitous Posttranslational Modification
T Klein, U Eckhard, A Dufour, N Solis, CM Overall
Chemical reviews 118 (3), 1137-1168, 2018
Mandati: National Health and Medical Research Council, Australia, Canadian Institutes …
An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient
J Quancard, T Klein, SY Fung, M Renatus, N Hughes, L Israël, JJ Priatel, ...
Nature chemical biology 15 (3), 304-313, 2019
Mandati: Canadian Institutes of Health Research, Natural Sciences and Engineering …
Global profiling of proteolysis from the mitochondrial amino terminome during early intrinsic apoptosis prior to caspase-3 activation
NC Marshall, T Klein, M Thejoe, N von Krosigk, J Kizhakkedathu, ...
Journal of proteome research 17 (12), 4279-4296, 2018
Mandati: Canadian Institutes of Health Research, Natural Sciences and Engineering …
Disponibili pubblicamente: 20
Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic …
U Eckhard, PF Huesgen, O Schilling, CL Bellac, GS Butler, JH Cox, ...
Matrix biology 49, 37-60, 2016
Mandati: Swiss National Science Foundation, Canadian Institutes of Health Research …
The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling
T Klein, SY Fung, F Renner, MA Blank, A Dufour, S Kang, M Bolger-Munro, ...
Nature communications 6 (1), 8777, 2015
Mandati: Canadian Institutes of Health Research, Natural Sciences and Engineering …
SEPIA–a new single pixel receiver at the APEX telescope
V Belitsky, I Lapkin, M Fredrixon, D Meledin, E Sundin, B Billade, SE Ferm, ...
Astronomy & astrophysics 612, A23, 2018
Mandati: US National Science Foundation
C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease
A Dufour, CL Bellac, U Eckhard, N Solis, T Klein, R Kappelhoff, N Fortelny, ...
Nature Communications 9 (1), 2416, 2018
Mandati: Canadian Institutes of Health Research, Natural Sciences and Engineering …
N-terminomics TAILS identifies host cell substrates of poliovirus and coxsackievirus B3 3C proteinases that modulate virus infection
JM Jagdeo, A Dufour, T Klein, N Solis, O Kleifeld, J Kizhakkedathu, H Luo, ...
Journal of virology 92 (8), 10.1128/jvi. 02211-17, 2018
Mandati: Canadian Institutes of Health Research, Natural Sciences and Engineering …
Cross-laboratory standardization of preclinical lipidomics using differential mobility spectrometry and multiple reaction monitoring
M Ghorasaini, Y Mohammed, J Adamski, L Bettcher, JA Bowden, ...
Analytical Chemistry 93 (49), 16369-16378, 2021
Mandati: US National Institutes of Health, Netherlands Organisation for Scientific …
Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction
V Russo, T Klein, DJ Lim, N Solis, Y Machado, S Hiroyasu, L Nabai, ...
Scientific reports 8 (1), 9690, 2018
Mandati: Canadian Institutes of Health Research, Natural Sciences and Engineering …
DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics
V Tam, P Chen, A Yee, N Solis, T Klein, M Kudelko, R Sharma, ...
Elife 9, e64940, 2020
Mandati: Canadian Institutes of Health Research, Research Grants Council, Hong Kong
Lipid signature of advanced human carotid atherosclerosis assessed by mass spectrometry imaging
AM Moerman, M Visscher, N Slijkhuis, K Van Gaalen, B Heijs, T Klein, ...
Journal of lipid research 62, 2021
Mandati: Netherlands Organisation for Scientific Research, Netherlands Organisation …
Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14
U Eckhard, PF Huesgen, O Schilling, CL Bellac, GS Butler, JH Cox, ...
Data in brief 7, 299-310, 2016
Mandati: Swiss National Science Foundation, Canadian Institutes of Health Research …
TAILS proteomics reveals dynamic changes in airway proteolysis controlling protease activity and innate immunity during COPD exacerbations
B Mallia-Milanes, A Dufour, C Philp, N Solis, T Klein, M Fischer, CE Bolton, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 315 (6 …, 2018
Mandati: National Health and Medical Research Council, Australia, Canadian Institutes …
Lower plasma melatonin levels predict worse long-term survival in pulmonary arterial hypertension
Z Cai, T Klein, LW Geenen, L Tu, S Tian, AE van den Bosch, YB de Rijke, ...
Journal of clinical medicine 9 (5), 1248, 2020
Mandati: German Research Foundation, Dutch Heart Foundation
MMP8 increases tongue carcinoma cell–cell adhesion and diminishes migration via cleavage of anti-adhesive FXYD5
K Juurikka, A Dufour, K Pehkonen, B Mainoli, P Campioni Rodrigues, ...
Oncogenesis 10 (5), 44, 2021
Mandati: Canadian Institutes of Health Research, Natural Sciences and Engineering …
Quantitative proteomics and terminomics to elucidate the role of ubiquitination and proteolysis in adaptive immunity
T Klein, RI Viner, CM Overall
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2016
Mandati: Canadian Institutes of Health Research
Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Rα
Z Cai, S Tian, T Klein, L Tu, LW Geenen, T Koudstaal, AE van den Bosch, ...
Scientific Reports 12 (1), 12326, 2022
Mandati: National Natural Science Foundation of China, German Research Foundation …
MALT1-Dependent cleavage of HOIL1 modulates canonical NF-κB signaling and inflammatory responsiveness
SY Fung, HY Lu, M Sharma, AA Sharma, A Saferali, A Jia, L Abraham, ...
Frontiers in Immunology 12, 749794, 2021
Mandati: US National Institutes of Health, Canadian Institutes of Health Research …
Master sculptor at work: enteropathogenic Escherichia coli infection uniquely modifies mitochondrial proteolysis during its control of human cell death
NC Marshall, M Thejoe, T Klein, A Serapio-Palacios, AS Santos, ...
Msystems 5 (3), 10.1128/msystems. 00283-20, 2020
Mandati: Canadian Institutes of Health Research, Genome Canada, Natural Sciences and …
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