| Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors K Takahashi, S Yamanaka cell 126 (4), 663-676, 2006 | 33723 | 2006 |
| Induction of pluripotent stem cells from adult human fibroblasts by defined factors K Takahashi, K Tanabe, M Ohnuki, M Narita, T Ichisaka, K Tomoda, ... cell 131 (5), 861-872, 2007 | 25448 | 2007 |
| The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells K Mitsui, Y Tokuzawa, H Itoh, K Segawa, M Murakami, K Takahashi, ... Cell 113 (5), 631-642, 2003 | 4219 | 2003 |
| Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts M Nakagawa, M Koyanagi, K Tanabe, K Takahashi, T Ichisaka, T Aoi, ... Nature biotechnology 26 (1), 101-106, 2008 | 3862 | 2008 |
| Suppression of induced pluripotent stem cell generation by the p53–p21 pathway H Hong, K Takahashi, T Ichisaka, T Aoi, O Kanagawa, M Nakagawa, ... Nature 460 (7259), 1132-1135, 2009 | 1605 | 2009 |
| Generation of pluripotent stem cells from adult mouse liver and stomach cells T Aoi, K Yae, M Nakagawa, T Ichisaka, K Okita, K Takahashi, T Chiba, ... Science 321 (5889), 699-702, 2008 | 1534 | 2008 |
| Induction of pluripotent stem cells from fibroblast cultures K Takahashi, K Okita, M Nakagawa, S Yamanaka Nature protocols 2 (12), 3081-3089, 2007 | 1365 | 2007 |
| Variation in the safety of induced pluripotent stem cell lines K Miura, Y Okada, T Aoi, A Okada, K Takahashi, K Okita, M Nakagawa, ... Nature biotechnology 27 (8), 743-745, 2009 | 1120 | 2009 |
| Hypoxia enhances the generation of induced pluripotent stem cells Y Yoshida, K Takahashi, K Okita, T Ichisaka, S Yamanaka Cell stem cell 5 (3), 237-241, 2009 | 1043 | 2009 |
| A decade of transcription factor-mediated reprogramming to pluripotency K Takahashi, S Yamanaka Nature reviews Molecular cell biology 17 (3), 183-193, 2016 | 932 | 2016 |
| Modeling Alzheimer’s disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness T Kondo, M Asai, K Tsukita, Y Kutoku, Y Ohsawa, Y Sunada, K Imamura, ... Cell stem cell 12 (4), 487-496, 2013 | 899 | 2013 |
| Drug screening for ALS using patient-specific induced pluripotent stem cells N Egawa, S Kitaoka, K Tsukita, M Naitoh, K Takahashi, T Yamamoto, ... Science translational medicine 4 (145), 145ra104-145ra104, 2012 | 655 | 2012 |
| Generation of retinal cells from mouse and human induced pluripotent stem cells Y Hirami, F Osakada, K Takahashi, K Okita, S Yamanaka, H Ikeda, ... Neuroscience letters 458 (3), 126-131, 2009 | 527 | 2009 |
| Robust in vitro induction of human germ cell fate from pluripotent stem cells K Sasaki, S Yokobayashi, T Nakamura, I Okamoto, Y Yabuta, K Kurimoto, ... Cell stem cell 17 (2), 178-194, 2015 | 508 | 2015 |
| Role of ERas in promoting tumour-like properties in mouse embryonic stem cells K Takahashi, K Mitsui, S Yamanaka Nature 423 (6939), 541-545, 2003 | 436 | 2003 |
| Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells N Takayama, S Nishimura, S Nakamura, T Shimizu, R Ohnishi, H Endo, ... Journal of Experimental Medicine 207 (13), 2817-2830, 2010 | 398 | 2010 |
| Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development Y Tokuzawa, E Kaiho, M Maruyama, K Takahashi, K Mitsui, M Maeda, ... Molecular and cellular biology 23 (8), 2699-2708, 2003 | 380 | 2003 |
| Induced pluripotent stem cells in medicine and biology K Takahashi, S Yamanaka Development 140 (12), 2457-2461, 2013 | 364 | 2013 |
| Induced pluripotent stem cells and their use in human models of disease and development P Karagiannis, K Takahashi, M Saito, Y Yoshida, K Okita, A Watanabe, ... Physiological reviews 99 (1), 79-114, 2019 | 352 | 2019 |
| Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells SI Mae, A Shono, F Shiota, T Yasuno, M Kajiwara, N Gotoda-Nishimura, ... Nature communications 4 (1), 1367, 2013 | 341 | 2013 |