Articoli con mandati relativi all'accesso pubblico - Roberto SanchezUlteriori informazioni
Non disponibile pubblicamente: 1
Catalyst-free synthesis of fused triazolo-diazepino [5, 6-b] quinoline derivatives via a sequential Ugi-4CR–nucleophilic substitution–intramolecular Click reaction
S Balalaie, A Vaezghaemi, N Zarezadeh, F Rominger, HR Bijanzadeh
Synlett 29 (08), 1095-1101, 2018
Mandati: UK Medical Research Council
Disponibili pubblicamente: 51
The PHD finger: a versatile epigenome reader
R Sanchez, MM Zhou
Trends in biochemical sciences 36 (7), 364-372, 2011
Mandati: US National Institutes of Health
The role of human bromodomains in chromatin biology and gene transcription
R Sanchez, MM Zhou
Current opinion in drug discovery & development 12 (5), 659, 2009
Mandati: US National Institutes of Health
A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication
P Wang, JC Alvarez-Perez, DP Felsenfeld, H Liu, S Sivendran, A Bender, ...
Nature medicine 21 (4), 383-388, 2015
Mandati: US National Institutes of Health, Juvenile Diabetes Research Foundation
SITEHOUND-web: a server for ligand binding site identification in protein structures
M Hernandez, D Ghersi, R Sanchez
Nucleic acids research 37 (suppl_2), W413-W416, 2009
Mandati: US National Institutes of Health
The bromodomain: from epigenome reader to druggable target
R Sanchez, J Meslamani, MM Zhou
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (8), 676-685, 2014
Mandati: US National Institutes of Health
Modern homology modeling of G-protein coupled receptors: which structural template to use?
JC Mobarec, R Sanchez, M Filizola
Journal of medicinal chemistry 52 (16), 5207-5216, 2009
Mandati: US National Institutes of Health
Outcome of a workshop on applications of protein models in biomedical research
T Schwede, A Sali, B Honig, M Levitt, HM Berman, D Jones, SE Brenner, ...
Structure 17 (2), 151-159, 2009
Mandati: US National Institutes of Health
Improving accuracy and efficiency of blind protein‐ligand docking by focusing on predicted binding sites
D Ghersi, R Sanchez
Proteins: Structure, Function, and Bioinformatics 74 (2), 417-424, 2009
Mandati: US National Institutes of Health
Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure
C Kho, A Lee, D Jeong, JG Oh, PA Gorski, K Fish, R Sanchez, RJ DeVita, ...
Nature communications 6 (1), 7229, 2015
Mandati: US National Institutes of Health
GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration
C Ackeifi, P Wang, E Karakose, JE Manning Fox, BJ González, H Liu, ...
Science translational medicine 12 (530), eaaw9996, 2020
Mandati: US National Institutes of Health, Juvenile Diabetes Research Foundation
Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis
MV Maddali, M Churpek, T Pham, E Rezoagli, H Zhuo, W Zhao, J He, ...
The Lancet Respiratory Medicine 10 (4), 367-377, 2022
Mandati: US Department of Defense, US National Institutes of Health
Privileged diazepine compounds and their emergence as bromodomain inhibitors
SG Smith, R Sanchez, MM Zhou
Chemistry & biology 21 (5), 573-583, 2014
Mandati: US National Institutes of Health
EasyMIFs and SiteHound: a toolkit for the identification of ligand-binding sites in protein structures
D Ghersi, R Sanchez
Bioinformatics 25 (23), 3185-3186, 2009
Mandati: US National Institutes of Health
Development of kinase-selective, harmine-based DYRK1A inhibitors that induce pancreatic human β-cell proliferation
K Kumar, P Wang, R Sanchez, EA Swartz, AF Stewart, RJ DeVita
Journal of medicinal chemistry 61 (17), 7687-7699, 2018
Mandati: US National Institutes of Health, Juvenile Diabetes Research Foundation
Beyond structural genomics: computational approaches for the identification of ligand binding sites in protein structures
D Ghersi, R Sanchez
Journal of structural and functional genomics 12, 109-117, 2011
Mandati: US National Institutes of Health
An NR2F1-specific agonist suppresses metastasis by inducing cancer cell dormancy
BD Khalil, R Sanchez, T Rahman, C Rodriguez-Tirado, S Moritsch, ...
Journal of Experimental Medicine 219 (1), e20210836, 2021
Mandati: US National Institutes of Health, Fundação para a Ciência e a Tecnologia …
Dissecting the contributions of cooperating gene mutations to cancer phenotypes and drug responses with patient-derived iPSCs
CJ Chang, AG Kotini, M Olszewska, M Georgomanoli, J Teruya-Feldstein, ...
Stem Cell Reports 10 (5), 1610-1624, 2018
Mandati: US Department of Defense, US National Institutes of Health, Damon Runyon …
Synthesis and biological validation of a harmine-based, central nervous system (CNS)-avoidant, selective, human β-cell regenerative dual-specificity tyrosine phosphorylation …
K Kumar, P Wang, J Wilson, V Zlatanic, C Berrouet, S Khamrui, C Secor, ...
Journal of medicinal chemistry 63 (6), 2986-3003, 2020
Mandati: US Department of Energy, US National Institutes of Health, Juvenile Diabetes …
Suramin inhibits cullin-RING E3 ubiquitin ligases
K Wu, RA Chong, Q Yu, J Bai, DE Spratt, K Ching, C Lee, H Miao, I Tappin, ...
Proceedings of the National Academy of Sciences 113 (14), E2011-E2018, 2016
Mandati: US National Institutes of Health, Canadian Institutes of Health Research …
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