Dorsal root ganglion neurons innervating skeletal muscle respond to physiological combinations of protons, ATP, and lactate mediated by ASIC, P2X, and TRPV1 AR Light, RW Hughen, J Zhang, J Rainier, Z Liu, J Lee Journal of neurophysiology 100 (3), 1184-1201, 2008 | 332 | 2008 |
Uric acid induces endothelial dysfunction by vascular insulin resistance associated with the impairment of nitric oxide synthesis YJ Choi, Y Yoon, KY Lee, TT Hien, KW Kang, KC Kim, J Lee, MY Lee, ... The FASEB Journal 28 (7), 3197-3204, 2014 | 255 | 2014 |
Migration of neutrophils targeting amyloid plaques in Alzheimer's disease mouse model SH Baik, MY Cha, YM Hyun, H Cho, B Hamza, DK Kim, SH Han, H Choi, ... Neurobiology of aging 35 (6), 1286-1292, 2014 | 177 | 2014 |
N-(3-Acyloxy-2-benzylpropyl)-N‘-[4-(methylsulfonylamino)benzyl]thiourea Analogues: Novel Potent and High Affinity Antagonists and Partial Antagonists of the … J Lee, J Lee, M Kang, M Shin, JM Kim, SU Kang, JO Lim, HK Choi, ... Journal of medicinal chemistry 46 (14), 3116-3126, 2003 | 170 | 2003 |
Lovastatin enhances Aβ production and senile plaque deposition in female Tg2576 mice IH Park, EM Hwang, HS Hong, JH Boo, SS Oh, J Lee, MW Jung, OY Bang, ... Neurobiology of aging 24 (5), 637-643, 2003 | 152 | 2003 |
Diacylglycerol (DAG)-lactones, a new class of protein kinase C (PKC) agonists, induce apoptosis in LNCaP prostate cancer cells by selective activation of PKCα ML Garcia-Bermejo, FC Leskow, T Fujii, Q Wang, PM Blumberg, M Ohba, ... Journal of Biological Chemistry 277 (1), 645-655, 2002 | 138 | 2002 |
High affinity antagonists of the vanilloid receptor Y Wang, T Szabo, JD Welter, A Toth, R Tran, J Lee, SU Kang, YG Suh, ... Molecular pharmacology 62 (4), 947-956, 2002 | 131 | 2002 |
Calcium‐dependent and independent mechanisms of capsaicin receptor (TRPV1)‐mediated cytokine production and cell death in human bronchial epithelial cells CA Reilly, ME Johansen, DL Lanza, J Lee, JO Lim, GS Yost Journal of biochemical and molecular toxicology 19 (4), 266-275, 2005 | 103 | 2005 |
Conformationally constrained analogues of diacylglycerol (DAG). 16. How much structural complexity is necessary for recognition and high binding affinity to protein kinase C? K Nacro, B Bienfait, J Lee, KC Han, JH Kang, S Benzaria, NE Lewin, ... Journal of medicinal chemistry 43 (5), 921-944, 2000 | 95 | 2000 |
Anti-tumor promoting potential of naturally occurring diarylheptanoids structurally related to curcumin KS Chun, Y Sohn, HS Kim, OH Kim, KK Park, JM Lee, J Lee, JY Lee, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 428 (1 …, 1999 | 95 | 1999 |
Inhibition of mouse skin tumor promotion by anti-inflammatory diarylheptanoids derived from Alpinia oxyphylla Miquel (Zingiberaceae). KS Chun, KK Park, J Lee, M Kang, YJ Surh Oncology research 13 (1), 37-45, 2002 | 91 | 2002 |
Transient receptor potential vanilloid type 1 antagonists: a patent review (2011–2014) Y Lee, S Hong, M Cui, PK Sharma, J Lee, S Choi Expert opinion on therapeutic patents 25 (3), 291-318, 2015 | 83 | 2015 |
Distinct structure-activity relations for stimulation of 45Ca uptake and for high affinity binding in cultured rat dorsal root ganglion neurons and dorsal root ganglion membranes G Acs, J Lee, VE Marquez, PM Blumberg Molecular brain research 35 (1-2), 173-182, 1996 | 83 | 1996 |
Curcumin interacts directly with the Cysteine 259 residue of STAT3 and induces apoptosis in H-Ras transformed human mammary epithelial cells YI Hahn, SJ Kim, BY Choi, KC Cho, R Bandu, KP Kim, DH Kim, W Kim, ... Scientific Reports 8 (1), 6409, 2018 | 80 | 2018 |
Structural insights into transient receptor potential vanilloid type 1 (TRPV1) from homology modeling, flexible docking, and mutational studies JH Lee, Y Lee, HC Ryu, DW Kang, J Lee, J Lazar, LV Pearce, ... Journal of computer-aided molecular design 25, 317-327, 2011 | 80 | 2011 |
Pyrazole-5-carboxamides, novel inhibitors of receptor for advanced glycation end products (RAGE) YT Han, K Kim, GI Choi, H An, D Son, H Kim, HJ Ha, JH Son, SJ Chung, ... European journal of medicinal chemistry 79, 128-142, 2014 | 76 | 2014 |
Ligand-based design, synthesis, and biological evaluation of 2-aminopyrimidines, a novel series of receptor for advanced glycation end products (RAGE) inhibitors YT Han, GI Choi, D Son, NJ Kim, H Yun, S Lee, DJ Chang, HS Hong, ... Journal of medicinal chemistry 55 (21), 9120-9135, 2012 | 74 | 2012 |
N-(3-Acyloxy-2-benzylpropyl)-N′-(4-hydroxy-3-methoxybenzyl) thiourea derivatives as potent vanilloid receptor agonists and analgesics J Lee, J Lee, J Kim, SY Kim, MW Chun, H Cho, SW Hwang, U Oh, ... Bioorganic & medicinal chemistry 9 (1), 19-32, 2001 | 73 | 2001 |
Transient receptor potential vanilloid-1 (TRPV1) is a mediator of lung toxicity for coal fly ash particulate material CE Deering-Rice, ME Johansen, JK Roberts, KC Thomas, EG Romero, ... Molecular pharmacology 81 (3), 411-419, 2012 | 72 | 2012 |
Curcumin suppresses oncogenicity of human colon cancer cells by covalently modifying the cysteine 67 residue of SIRT1 YH Lee, NY Song, J Suh, DH Kim, W Kim, J Ann, J Lee, JH Baek, HK Na, ... Cancer letters 431, 219-229, 2018 | 70 | 2018 |