| Detection of circulating tumor DNA in early-and late-stage human malignancies C Bettegowda, M Sausen, RJ Leary, I Kinde, Y Wang, N Agrawal, ... Science translational medicine 6 (224), 224ra24-224ra24, 2014 | 4989 | 2014 |
| Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas H Brem, S Piantadosi, PC Burger, M Walker, R Selker, NA Vick, K Black, ... The Lancet 345 (8956), 1008-1012, 1995 | 1750 | 1995 |
| Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells SGM Piccirillo, BA Reynolds, N Zanetti, G Lamorte, E Binda, G Broggi, ... Nature 444 (7120), 761-765, 2006 | 1474 | 2006 |
| Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas J Zeng, AP See, J Phallen, CM Jackson, Z Belcaid, J Ruzevick, N Durham, ... International Journal of Radiation Oncology* Biology* Physics 86 (2), 343-349, 2013 | 1044 | 2013 |
| Polylactic acid (PLA) controlled delivery carriers for biomedical applications B Tyler, D Gullotti, A Mangraviti, T Utsuki, H Brem Advanced drug delivery reviews 107, 163-175, 2016 | 996 | 2016 |
| Independent association of extent of resection with survival in patients with malignant brain astrocytoma MJ McGirt, KL Chaichana, M Gathinji, FJ Attenello, K Than, A Olivi, ... Journal of neurosurgery 110 (1), 156-162, 2009 | 921 | 2009 |
| Survival following surgery and prognostic factors for recently diagnosed malignant glioma: data from the Glioma Outcomes Project ER Laws, IF Parney, W Huang, F Anderson, AM Morris, A Asher, ... Journal of neurosurgery 99 (3), 467-473, 2003 | 917 | 2003 |
| Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas H Brem, MS Mahaley, NA Vick, KL Black, SC Schold, PC Burger, ... Journal of neurosurgery 74 (3), 441-446, 1991 | 671 | 1991 |
| Multi-pulse drug delivery from a resorbable polymeric microchip device ACR Grayson, IS Choi, BM Tyler, PP Wang, H Brem, MJ Cima, R Langer Nature materials 2 (11), 767-772, 2003 | 651 | 2003 |
| Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas MJ McGirt, KL Chaichana, FJ Attenello, JD Weingart, K Than, PC Burger, ... Neurosurgery 63 (4), 700-708, 2008 | 635 | 2008 |
| Inhibition of tumor angiogenesis mediated by cartilage. H Brem, J Folkman The Journal of experimental medicine 141 (2), 427-439, 1975 | 556 | 1975 |
| Establishing percent resection and residual volume thresholds affecting survival and recurrence for patients with newly diagnosed intracranial glioblastoma KL Chaichana, I Jusue-Torres, R Navarro-Ramirez, SM Raza, ... Neuro-oncology 16 (1), 113-122, 2014 | 554 | 2014 |
| Paclitaxel: a review of adverse toxicities and novel delivery strategies NI Marupudi, JE Han, KW Li, VM Renard, BM Tyler, H Brem Expert opinion on drug safety 6 (5), 609-621, 2007 | 549 | 2007 |
| Patterns of care for adults with newly diagnosed malignant glioma SM Chang, IF Parney, W Huang, FA Anderson, AL Asher, M Bernstein, ... Jama 293 (5), 557-564, 2005 | 485 | 2005 |
| Hemangioblastomas of the central nervous system in von Hippel-Lindau syndrome and sporadic disease JE Conway, D Chou, RE Clatterbuck, H Brem, DM Long, D Rigamonti Neurosurgery 48 (1), 55-63, 2001 | 468 | 2001 |
| Advancing the field of drug delivery: taking aim at cancer MA Moses, H Brem, R Langer Cancer cell 4 (5), 337-341, 2003 | 465 | 2003 |
| Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord Y Wang, S Springer, M Zhang, KW McMahon, I Kinde, L Dobbyn, J Ptak, ... Proceedings of the National Academy of Sciences 112 (31), 9704-9709, 2015 | 459 | 2015 |
| Controlled local delivery of chemotherapeutic agents for treating solid tumors H Brem, RS Langer, AJ Domb US Patent 5,626,862, 1997 | 451 | 1997 |
| Combination therapy with anti-PD-1, anti-TIM-3, and focal radiation results in regression of murine gliomas JE Kim, MA Patel, A Mangraviti, ES Kim, D Theodros, E Velarde, A Liu, ... Clinical Cancer Research 23 (1), 124-136, 2017 | 448 | 2017 |
| Isolations of a cartilage factor that inhibits tumor neovascularization R Langer, H Brem, K Falterman, M Klein, J Folkman Science 193 (4247), 70-72, 1976 | 448 | 1976 |
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