| Designed multiple ligands. An emerging drug discovery paradigm R Morphy, Z Rankovic Journal of medicinal chemistry 48 (21), 6523-6543, 2005 | 1446 | 2005 |
| From magic bullets to designed multiple ligands R Morphy, C Kay, Z Rankovic Drug discovery today 9 (15), 641-651, 2004 | 917 | 2004 |
| CNS drug design: balancing physicochemical properties for optimal brain exposure Z Rankovic Journal of medicinal chemistry 58 (6), 2584-2608, 2015 | 518 | 2015 |
| Medicinal chemistry of hERG optimizations: highlights and hang-ups C Jamieson, EM Moir, Z Rankovic, G Wishart Journal of medicinal chemistry 49 (17), 5029-5046, 2006 | 443 | 2006 |
| Designing multiple ligands-medicinal chemistry strategies and challenges R Morphy, Z Rankovic Current pharmaceutical design 15 (6), 587-600, 2009 | 338 | 2009 |
| Biased agonism: An emerging paradigm in GPCR drug discovery Z Rankovic, TF Brust, LM Bohn Bioorganic & medicinal chemistry letters 26 (2), 241-250, 2016 | 300 | 2016 |
| Fragments, network biology and designing multiple ligands R Morphy, Z Rankovic Drug discovery today 12 (3-4), 156-160, 2007 | 269 | 2007 |
| The physicochemical challenges of designing multiple ligands R Morphy, Z Rankovic Journal of Medicinal Chemistry 49 (16), 4961-4970, 2006 | 249 | 2006 |
| Synthesis of tertiary amines using a polystyrene (REM) resin AR Brown, DC Rees, Z Rankovic, JR Morphy Journal of the American Chemical Society 119 (14), 3288-3295, 1997 | 159 | 1997 |
| A novel linker strategy for solid-phase synthesis JR Morphy, Z Rankovic, DC Rees Tetrahedron letters 37 (18), 3209-3212, 1996 | 142 | 1996 |
| The first potent and selective inhibitors of the glycine transporter type 2 WL Caulfield, IT Collie, RS Dickins, O Epemolu, R McGuire, DR Hill, ... Journal of medicinal chemistry 44 (17), 2679-2682, 2001 | 124 | 2001 |
| New pyridine N-oxides as chiral organocatalysts in the asymmetric allylation of aromatic aldehydes AV Malkov, MM Westwater, A Gutnov, P Ramírez-López, F Friscourt, ... Tetrahedron 64 (49), 11335-11348, 2008 | 111 | 2008 |
| CNS physicochemical property space shaped by a diverse set of molecules with experimentally determined exposure in the mouse brain: miniperspective Z Rankovic Journal of Medicinal Chemistry 60 (14), 5943-5954, 2017 | 93 | 2017 |
| Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs J Min, A Mayasundari, F Keramatnia, B Jonchere, SW Yang, J Jarusiewicz, ... Angewandte Chemie International Edition 60 (51), 26663-26670, 2021 | 90 | 2021 |
| Identification of potent, selective, and orally bioavailable small-molecule GSPT1/2 degraders from a focused library of cereblon modulators G Nishiguchi, F Keramatnia, J Min, Y Chang, B Jonchere, S Das, M Actis, ... Journal of medicinal chemistry 64 (11), 7296-7311, 2021 | 68 | 2021 |
| Fused and bridged bi-and tri-cyclic lactams via sequential metallo-azomethine ylide cycloaddition–lactamisation P Blaney, R Grigg, Z Rankovic, M Thornton-Pett, J Xu Tetrahedron 58 (9), 1719-1737, 2002 | 53 | 2002 |
| Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia Y Chang, J Min, JA Jarusiewicz, M Actis, S Yu-Chen Bradford, ... Blood, The Journal of the American Society of Hematology 138 (23), 2313-2326, 2021 | 51 | 2021 |
| Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma C He, K Xu, X Zhu, PS Dunphy, B Gudenas, W Lin, N Twarog, LD Hover, ... Nature communications 12 (1), 4089, 2021 | 47 | 2021 |
| A novel series of positive modulators of the AMPA receptor: discovery and structure based hit-to-lead studies C Jamieson, S Basten, RA Campbell, IA Cumming, KJ Gillen, J Gillespie, ... Bioorganic & medicinal chemistry letters 20 (19), 5753-5756, 2010 | 44 | 2010 |
| Positive allosteric modulators of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor SJA Grove, C Jamieson, JKF Maclean, JA Morrow, Z Rankovic Journal of medicinal chemistry 53 (20), 7271-7279, 2010 | 41 | 2010 |
