Regulation of the actin cytoskeleton-plasma membrane interplay by phosphoinositides J Saarikangas, H Zhao, P Lappalainen Physiological reviews 90 (1), 259-289, 2010 | 591 | 2010 |
Missing-in-metastasis and IRSp53 deform PI(4,5)P2-rich membranes by an inverse BAR domain–like mechanism PK Mattila, A Pykalainen, J Saarikangas, VO Paavilainen, H Vihinen, ... The Journal of cell biology 176 (7), 953-964, 2007 | 461 | 2007 |
Molecular mechanisms of membrane deformation by I-BAR domain proteins J Saarikangas, H Zhao, A Pykäläinen, P Laurinmäki, PK Mattila, ... Current biology 19 (2), 95-107, 2009 | 365 | 2009 |
Protein aggregates are associated with replicative aging without compromising protein quality control J Saarikangas, Y Barral Elife 4, e06197, 2015 | 160 | 2015 |
The emerging functions of septins in metazoans J Saarikangas, Y Barral EMBO reports 12 (11), 1118-1126, 2011 | 151 | 2011 |
Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures A Pykäläinen, M Boczkowska, H Zhao, J Saarikangas, G Rebowski, ... Nature structural & molecular biology 18 (8), 902-907, 2011 | 104 | 2011 |
Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia J Saarikangas, PK Mattila, M Varjosalo, M Bovellan, J Hakanen, ... Journal of cell science 124 (8), 1245-1255, 2011 | 102 | 2011 |
MIM-induced membrane bending promotes dendritic spine initiation J Saarikangas, N Kourdougli, Y Senju, G Chazal, M Segerstråle, ... Developmental cell 33 (6), 644-659, 2015 | 89 | 2015 |
ABBA regulates plasma-membrane and actin dynamics to promote radial glia extension J Saarikangas, J Hakanen, PK Mattila, M Grumet, M Salminen, ... Journal of cell science 121 (9), 1444-1454, 2008 | 82 | 2008 |
Protein aggregation as a mechanism of adaptive cellular responses J Saarikangas, Y Barral Current genetics 62, 711-724, 2016 | 77 | 2016 |
MTSS1 is a metastasis driver in a subset of human melanomas KD Mertz, G Pathria, C Wagner, J Saarikangas, A Sboner, J Romanov, ... Nature communications 5 (1), 3465, 2014 | 73 | 2014 |
cAMP signaling by anthrax edema toxin induces transendothelial cell tunnels, which are resealed by MIM via Arp2/3-driven actin polymerization MP Maddugoda, C Stefani, D Gonzalez-Rodriguez, J Saarikangas, ... Cell host & microbe 10 (5), 464-474, 2011 | 73 | 2011 |
Compartmentalization of ER-bound chaperone confines protein deposit formation to the aging yeast cell J Saarikangas, F Caudron, R Prasad, DF Moreno, A Bolognesi, M Aldea, ... Current Biology 27 (6), 773-783, 2017 | 66 | 2017 |
Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity J Paukštytė, RML Cabezas, Y Feng, K Tong, D Schnyder, E Elomaa, ... Molecular Cell 83 (18), 3360-3376. e11, 2023 | 14 | 2023 |
Chaperoning junior faculty: Institutional support and guidance can relieve challenges for early‐career group leaders and improve academic performance R Sawarkar, R Scherz‐Shouval, MS Denzel, J Saarikangas EMBO reports 20 (1), e47163, 2019 | 10 | 2019 |
Whi3 mnemon association with endoplasmic reticulum membranes confines the memory of deceptive courtship to the yeast mother cell Y Lau, HP Oamen, M Grogg, I Parfenova, J Saarikangas, R Hannay, ... Current Biology 32 (5), 963-974. e7, 2022 | 7 | 2022 |
Winter is coming: regulation of cellular metabolism by enzyme polymerization in dormancy and disease K Montrose, RML Cabezas, J Paukštytė, J Saarikangas Experimental Cell Research 397 (2), 112383, 2020 | 7 | 2020 |
Actin-rich lamellipodia-like protrusions contribute to the integrity of epithelial cell–cell junctions Y Senju, T Mushtaq, H Vihinen, A Manninen, J Saarikangas, K Ven, ... Journal of Biological Chemistry 299 (5), 2023 | 5 | 2023 |
Proteostatic tuning underpins the evolution of novel multicellular traits K Montrose, DT Lac, AJ Burnetti, K Tong, GO Bozdag, M Hukkanen, ... Science Advances 10 (10), eadn2706, 2024 | 4 | 2024 |
Spatial regulation of coalesced protein assemblies: Lessons from yeast to diseases J Saarikangas, F Caudron Prion 11 (3), 162-173, 2017 | 4 | 2017 |