Accesso pubblico

'Toxgnostics': an unmet need in cancer medicine

D Church, R Kerr, E Domingo, D Rosmarin, C Palles, K Maskell, ...

Nature Reviews Cancer 14 (6), 440-445, 2014

Mandati: Cancer Research UK, Wellcome Trust

Joint prediction of response to therapy, molecular traits, and spatial organisation in colorectal cancer biopsies

R Wood, E Domingo, K Sirinukunwattana, MW Lafarge, VH Koelzer, ...

International Conference on Medical Image Computing and Computer-Assisted …, 2023

Mandati: Swiss National Science Foundation, Cancer Research UK, UK Engineering and …

Disponibili pubblicamente: 84

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

C Palles, JB Cazier, KM Howarth, E Domingo, AM Jones, P Broderick, ...

Nature genetics 45 (2), 136-144, 2013

Mandati: Cancer Research UK, Government of Spain

Replication stress links structural and numerical cancer chromosomal instability

RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ...

Nature 494 (7438), 492-496, 2013

Mandati: Swedish Research Council, Cancer Research UK

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23. 3

IPM Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, K Howarth, ...

Nature genetics 40 (5), 623-630, 2008

Mandati: Cancer Research UK, Chief Scientist Office, Scottish Executive

A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk

P Broderick, L Carvajal-Carmona, AM Pittman, E Webb, K Howarth, ...

Nature genetics 39 (11), 1315-1317, 2007

Mandati: Cancer Research UK

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

L Carvajal-Carmona, K Howarth, E Jaeger, SL Spain, A Walther, ...

Nature genetics 40 (12), 1426-1435, 2008

Mandati: US National Institutes of Health, Genome Canada, German Research Foundation …

[PDF] ed.ac.uk

Deep learning for prediction of colorectal cancer outcome: a discovery and validation study

OJ Skrede, S De Raedt, A Kleppe, TS Hveem, K Liestøl, J Maddison, ...

The Lancet 395 (10221), 350-360, 2020

Mandati: Cancer Research UK, National Institute for Health Research, UK, Research …

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26. 2, 12q13. 13 and 20q13. 33

RS Houlston, J Cheadle, SE Dobbins, A Tenesa, AM Jones, K Howarth, ...

Nature genetics 42 (11), 973-977, 2010

Mandati: Cancer Research UK, Chief Scientist Office, Scottish Executive

[HTML] oup.com

DNA polymerase ɛ and δ exonuclease domain mutations in endometrial cancer

DN Church, SEW Briggs, C Palles, E Domingo, SJ Kearsey, JM Grimes, ...

Human molecular genetics 22 (14), 2820-2828, 2013

Mandati: US National Institutes of Health, Cancer Research UK, Wellcome Trust

Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13. 3 influence colorectal cancer risk

E Jaeger, E Webb, K Howarth, L Carvajal-Carmona, A Rowan, ...

Nature genetics 40 (1), 26-28, 2008

Mandati: Cancer Research UK

[PDF] ucl.ac.uk

Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study

E Domingo, L Freeman-Mills, E Rayner, M Glaire, S Briggs, L Vermeulen, ...

The lancet Gastroenterology & hepatology 1 (3), 207-216, 2016

Mandati: Academy of Medical Sciences, UK, Cancer Research UK, National Institute for …

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

MG Dunlop, SE Dobbins, SM Farrington, AM Jones, C Palles, N Whiffin, ...

Nature genetics 44 (7), 770-776, 2012

Mandati: US National Institutes of Health, Swedish Research Council, Cancer Research …

Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis

D Rosmarin, C Palles, D Church, E Domingo, A Jones, E Johnstone, ...

Journal of Clinical Oncology 32 (10), 1031-1039, 2014

Mandati: US National Institutes of Health, Cancer Research UK, Wellcome Trust

Evaluation of PIK3CA Mutation As a Predictor of Benefit From Nonsteroidal Anti-Inflammatory Drug Therapy in Colorectal Cancer

E Domingo, DN Church, O Sieber, R Ramamoorthy, Y Yanagisawa, ...

Journal of clinical oncology 31 (34), 4297-4305, 2013

Mandati: Cancer Research UK, Wellcome Trust

[HTML] bmj.com

Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

K Sirinukunwattana, E Domingo, SD Richman, KL Redmond, A Blake, ...

Gut 70 (3), 544-554, 2021

Mandati: Swiss National Science Foundation, Cancer Research UK, UK Engineering and …

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

D Mouradov, E Domingo, P Gibbs, RN Jorissen, S Li, PY Soo, L Lipton, ...

Official journal of the American College of Gastroenterology| ACG 108 (11 …, 2013

Mandati: National Health and Medical Research Council, Australia, Cancer Research UK …

[PDF] ox.ac.uk

Adjuvant capecitabine plus bevacizumab versus capecitabine alone in patients with colorectal cancer (QUASAR 2): an open-label, randomised phase 3 trial

RS Kerr, S Love, E Segelov, E Johnstone, B Falcon, P Hewett, A Weaver, ...

The Lancet Oncology 17 (11), 1543-1557, 2016

Mandati: Cancer Research UK, National Institute for Health Research, UK, Wellcome Trust

[HTML] gastrojournal.org

Clonality assessment and clonal ordering of individual neoplastic crypts shows polyclonality of colorectal adenomas

C Thirlwell, OCC Will, E Domingo, TA Graham, SAC McDonald, D Oukrif, ...

Gastroenterology 138 (4), 1441-1454. e7, 2010

Mandati: Cancer Research UK

[HTML] cell.com