| Biophysical regulation of epigenetic state and cell reprogramming TL Downing, J Soto, C Morez, T Houssin, A Fritz, F Yuan, J Chu, S Patel, ... Nature materials 12 (12), 1154-1162, 2013 | 518 | 2013 |
| YAP-mediated mechanotransduction tunes the macrophage inflammatory response VS Meli, H Atcha, PK Veerasubramanian, RR Nagalla, TU Luu, EY Chen, ... Science advances 6 (49), eabb8471, 2020 | 203 | 2020 |
| Mechanoresponsive stem cells to target cancer metastases through biophysical cues L Liu, SX Zhang, W Liao, HP Farhoodi, CW Wong, CC Chen, AI Ségaliny, ... Science translational medicine 9 (400), eaan2966, 2017 | 111 | 2017 |
| Biophysical regulation of macrophages in health and disease VS Meli, PK Veerasubramanian, H Atcha, Z Reitz, TL Downing, WF Liu Journal of leukocyte biology 106 (2), 283-299, 2019 | 109 | 2019 |
| Human induced pluripotent stem cell-derived neural crest stem cells integrate into the injured spinal cord in the fetal lamb model of myelomeningocele P Saadai, A Wang, YS Nout, TL Downing, K Lofberg, MS Beattie, ... Journal of pediatric surgery 48 (1), 158-163, 2013 | 91 | 2013 |
| Global delay in nascent strand DNA methylation J Charlton, TL Downing, ZD Smith, H Gu, K Clement, R Pop, V Akopian, ... Nature structural & molecular biology 25 (4), 327-332, 2018 | 75 | 2018 |
| Drug-eluting microfibrous patches for the local delivery of rolipram in spinal cord repair TL Downing, A Wang, ZQ Yan, Y Nout, AL Lee, MS Beattie, JC Bresnahan, ... Journal of controlled release 161 (3), 910-917, 2012 | 56 | 2012 |
| Prenatal repair of myelomeningocele with aligned nanofibrous scaffolds—a pilot study in sheep P Saadai, YS Nout, J Encinas, A Wang, TL Downing, MS Beattie, ... Journal of pediatric surgery 46 (12), 2279-2283, 2011 | 54 | 2011 |
| Stochastic modeling reveals kinetic heterogeneity in post-replication DNA methylation L Busto-Moner, J Morival, H Ren, A Fahim, Z Reitz, TL Downing, EL Read PLoS computational biology 16 (4), e1007195, 2020 | 25 | 2020 |
| A Src-H3 acetylation signaling axis integrates macrophage mechanosensation with inflammatory response PK Veerasubramanian, H Shao, VS Meli, TAQ Phan, TU Luu, WF Liu, ... Biomaterials 279, 121236, 2021 | 16 | 2021 |
| Mechanosensation to inflammation: Roles for YAP/TAZ in innate immune cells VS Meli, PK Veerasubramanian, TL Downing, W Wang, WF Liu Science signaling 16 (783), eadc9656, 2023 | 13 | 2023 |
| The impact of age-related hypomethylated DNA on immune signaling upon cellular demise LA Urban, A Trinh, E Pearlman, A Siryaporn, TL Downing Trends in immunology 42 (6), 464-468, 2021 | 12 | 2021 |
| Reduction of intracellular tension and cell adhesion promotes open chromatin structure and enhances cell reprogramming J Soto, Y Song, Y Wu, B Chen, H Park, N Akhtar, PY Wang, T Hoffman, ... Advanced Science 10 (24), 2300152, 2023 | 10 | 2023 |
| DNA methylation analysis reveals epimutation hotspots in patients with dilated cardiomyopathy-associated laminopathies JLP Morival, HP Widyastuti, CHH Nguyen, MV Zaragoza, TL Downing Clinical epigenetics 13, 1-20, 2021 | 8 | 2021 |
| Biophysical and epigenetic regulation of cancer stemness, invasiveness, and immune action PK Veerasubramanian, A Trinh, N Akhtar, WF Liu, TL Downing Current tissue microenvironment reports 1, 277-300, 2020 | 7 | 2020 |
| Mechanotransduction to epigenetic remodeling D Kelkhoff, T Downing, S Li Molecular and cellular mechanobiology, 163-173, 2016 | 6 | 2016 |
| Characterization of macrophage and cytokine interactions with biomaterials used in negative-pressure wound therapy PK Veerasubramanian, VC Joe, WF Liu, TL Downing Bioengineering 9 (1), 2, 2021 | 5 | 2021 |
| Locally correlated kinetics of post-replication DNA methylation reveals processivity and region specificity in DNA methylation maintenance H Ren, RB Taylor, TL Downing, EL Read Journal of the Royal Society Interface 19 (195), 20220415, 2022 | 4 | 2022 |
| Examining age-dependent DNA methylation patterns and gene expression in the male and female mouse hippocampus CA Chinn, H Ren, JLP Morival, Q Nie, MA Wood, TL Downing Neurobiology of aging 108, 223-235, 2021 | 4 | 2021 |
| Biphasic regulation of epigenetic state by matrix stiffness during cell reprogramming Y Song, J Soto, SY Wong, Y Wu, T Hoffman, N Akhtar, S Norris, J Chu, ... Science Advances 10 (7), eadk0639, 2024 | 3 | 2024 |