In vivo genome editing using Staphylococcus aureus Cas9 FA Ran, L Cong, WX Yan, DA Scott, JS Gootenberg, AJ Kriz, B Zetsche, ... Nature 520 (7546), 186-191, 2015 | 3151 | 2015 |
Rationally engineered Cas9 nucleases with improved specificity IM Slaymaker, L Gao, B Zetsche, DA Scott, WX Yan, F Zhang Science 351 (6268), 84-88, 2016 | 2734 | 2016 |
Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants KS Makarova, YI Wolf, J Iranzo, SA Shmakov, OS Alkhnbashi, SJJ Brouns, ... Nature Reviews Microbiology 18 (2), 67-83, 2020 | 2102 | 2020 |
In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy CE Nelson, CH Hakim, DG Ousterout, PI Thakore, EA Moreb, RMC Rivera, ... Science 351 (6271), 403-407, 2016 | 1373 | 2016 |
In vivo gene editing in dystrophic mouse muscle and muscle stem cells M Tabebordbar, K Zhu, JKW Cheng, WL Chew, JJ Widrick, WX Yan, ... Science 351 (6271), 407-411, 2016 | 1245 | 2016 |
Diversity and evolution of class 2 CRISPR–Cas systems S Shmakov, A Smargon, D Scott, D Cox, N Pyzocha, W Yan, ... Nature reviews microbiology 15 (3), 169-182, 2017 | 1135 | 2017 |
Crystal structure of Staphylococcus aureus Cas9 H Nishimasu, L Cong, WX Yan, FA Ran, B Zetsche, Y Li, A Kurabayashi, ... Cell 162 (5), 1113-1126, 2015 | 509 | 2015 |
Engineered Cpf1 variants with altered PAM specificities L Gao, DBT Cox, WX Yan, JC Manteiga, MW Schneider, T Yamano, ... Nature biotechnology 35 (8), 789-792, 2017 | 476 | 2017 |
Functionally diverse type V CRISPR-Cas systems WX Yan, P Hunnewell, LE Alfonse, JM Carte, E Keston-Smith, ... Science 363 (6422), 88-91, 2019 | 468 | 2019 |
Cas13d is a compact RNA-targeting type VI CRISPR effector positively modulated by a WYL-domain-containing accessory protein WX Yan, S Chong, H Zhang, KS Makarova, EV Koonin, DR Cheng, ... Molecular cell 70 (2), 327-339. e5, 2018 | 457 | 2018 |
BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks WX Yan, R Mirzazadeh, S Garnerone, D Scott, MW Schneider, T Kallas, ... Nature communications 8 (1), 15058, 2017 | 370 | 2017 |
CRISPR–Cas in mobile genetic elements: counter-defence and beyond G Faure, SA Shmakov, WX Yan, DR Cheng, DA Scott, JE Peters, ... Nature Reviews Microbiology 17 (8), 513-525, 2019 | 261 | 2019 |
A machine learning approach for predicting CRISPR-Cas9 cleavage efficiencies and patterns underlying its mechanism of action S Abadi, WX Yan, D Amar, I Mayrose PLoS computational biology 13 (10), e1005807, 2017 | 205 | 2017 |
CRISPR-Cas9–based treatment of myocilin-associated glaucoma A Jain, G Zode, RB Kasetti, FA Ran, W Yan, TP Sharma, K Bugge, ... Proceedings of the National Academy of Sciences 114 (42), 11199-11204, 2017 | 196 | 2017 |
Reducing the gradient artefact in simultaneous EEG-fMRI by adjusting the subject's axial position KJ Mullinger, WX Yan, R Bowtell Neuroimage 54 (3), 1942-1950, 2011 | 89 | 2011 |
Understanding gradient artefacts in simultaneous EEG/fMRI WX Yan, KJ Mullinger, MJ Brookes, R Bowtell Neuroimage 46 (2), 459-471, 2009 | 88 | 2009 |
Physical modeling of pulse artefact sources in simultaneous EEG/fMRI WX Yan, KJ Mullinger, GB Geirsdottir, R Bowtell Human brain mapping 31 (4), 604-620, 2010 | 82 | 2010 |
Unbiased identification of double-strand breaks and genomic rearrangement by genome-wide insert capture sequencing F Zhang, W Yan, DA Scott, A Smargon, MR Mirzazadeh, N Crosetto US Patent 10,689,691, 2020 | 72 | 2020 |
Source localisation in concurrent EEG/fMRI: applications at 7T MJ Brookes, J Vrba, KJ Mullinger, GB Geirsdóttir, WX Yan, CM Stevenson, ... Neuroimage 45 (2), 440-452, 2009 | 49 | 2009 |
Percolative effects on noise in pentacene transistors BR Conrad, WG Cullen, W Yan, ED Williams Applied Physics Letters 91 (24), 2007 | 47 | 2007 |