Data-driven phenotypic dissection of AML reveals progenitor-like cells that correlate with prognosis JH Levine, EF Simonds, SC Bendall, KL Davis, DA El-ad, MD Tadmor, ... Cell 162 (1), 184-197, 2015 | 2135 | 2015 |
viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia ED Amir, KL Davis, MD Tadmor, EF Simonds, JH Levine, SC Bendall, ... Nature biotechnology 31 (6), 545-552, 2013 | 1618 | 2013 |
Distinct cellular mechanisms underlie anti-CTLA-4 and anti-PD-1 checkpoint blockade SC Wei, JH Levine, AP Cogdill, Y Zhao, NAAS Anang, MC Andrews, ... Cell 170 (6), 1120-1133. e17, 2017 | 1240 | 2017 |
Innate immune landscape in early lung adenocarcinoma by paired single-cell analyses Y Lavin, S Kobayashi, A Leader, ED Amir, N Elefant, C Bigenwald, ... Cell 169 (4), 750-765. e17, 2017 | 1116 | 2017 |
An immune atlas of clear cell renal cell carcinoma S Chevrier, JH Levine, VRT Zanotelli, K Silina, D Schulz, M Bacac, ... Cell 169 (4), 736-749. e18, 2017 | 948 | 2017 |
Characterization of cell fate probabilities in single-cell data with Palantir M Setty, V Kiseliovas, J Levine, A Gayoso, L Mazutis, D Pe’Er Nature biotechnology 37 (4), 451-460, 2019 | 499 | 2019 |
Combination anti–CTLA-4 plus anti–PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies SC Wei, NAAS Anang, R Sharma, MC Andrews, A Reuben, JH Levine, ... Proceedings of the National Academy of Sciences 116 (45), 22699-22709, 2019 | 313 | 2019 |
Persistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity RA Ihrie, JK Shah, CC Harwell, JH Levine, CD Guinto, M Lezameta, ... Neuron 71 (2), 250-262, 2011 | 302 | 2011 |
Environmental control of kisspeptin: implications for seasonal reproduction TJ Greives, AO Mason, MAL Scotti, J Levine, ED Ketterson, LJ Kriegsfeld, ... Endocrinology 148 (3), 1158-1166, 2007 | 259 | 2007 |
Suppression of kisspeptin expression and gonadotropic axis sensitivity following exposure to inhibitory day lengths in female Siberian hamsters AO Mason, TJ Greives, MAL Scotti, J Levine, S Frommeyer, ED Ketterson, ... Hormones and behavior 52 (4), 492-498, 2007 | 112 | 2007 |
Amir el JH Levine, EF Simonds, SC Bendall, KL Davis AD, Tadmor, MD, Litvin, O., Fienberg, HG, Jager, A., Zunder, ER, et al, 184-197, 2015 | 108 | 2015 |
Negative co-stimulation constrains T cell differentiation by imposing boundaries on possible cell states SC Wei, R Sharma, NAAS Anang, JH Levine, Y Zhao, JJ Mancuso, ... Immunity 50 (4), 1084-1098. e10, 2019 | 99 | 2019 |
Geographic atrophy in age-related macular degeneration and TLR3. R Allikmets, AA Bergen, M Dean, RH Guymer, GS Hageman, CC Klaver, ... The New England journal of medicine 360 (21), 2252-4; author reply 2255, 2009 | 44 | 2009 |
AD Amir el, MD Tadmor, O JH Levine, EF Simonds, SC Bendall, KL Davis Litvin, HG Fienberg, A. Jager, ER Zunder, R. Finck, AL Gedman, I. Radtke, JR …, 2015 | 40 | 2015 |
Palantir characterizes cell fate continuities in human hematopoiesis M Setty, V Kiseliovas, J Levine, A Gayoso, L Mazutis, D Pe’er BioRxiv, 385328, 2018 | 14 | 2018 |
Distinct cellular mechanisms mediate anti-CTLA-4 and anti-PD-1 checkpoint blockade SC Wei, JH Levine, D Pe'er, JP Allison Cancer Research 77 (13_Supplement), 592-592, 2017 | 1 | 2017 |
282 Improving solid tumor CAR-T therapies by modulating T cell transcriptional states using combinatorial in vitro CRISPR screening followed by in vivo validation LM Leon, AC Boroughs, A Cass, J Choe, A Cardozo, J Chow, ... Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024 | | 2024 |
Enhancing TCR T cell function in solid tumors through in vivo combinatorial screens and single-cell analysis D Polyak, J Fuhriman, J Susanto, A Merrell, M Simon, C Oh, A Cordazo, ... Cancer Research 84 (6_Supplement), 7042-7042, 2024 | | 2024 |
Pooled CRISPR screening coupled with single-cell sequencing identifies modifiers of CAR T cell state in the context of chronic antigen stimulation S Joshi, G Wozniak, J Gagnon, K Vucci, A Merrell, M Simon, C Oh, ... Cancer Research 84 (6_Supplement), 7034-7034, 2024 | | 2024 |
Negative costimulation constrains T cell differentiation SC Wei, R Sharma, NA Anang, J Levine, Y Zhao, J Wang, D Pe’er, ... The Journal of Immunology 200 (1_Supplement), 171.17-171.17, 2018 | | 2018 |