Identification of essential genes for cancer immunotherapy SJ Patel, NE Sanjana, RJ Kishton, A Eidizadeh, SK Vodnala, M Cam, ... Nature 548 (7669), 537-542, 2017 | 859 | 2017 |
Ionic immune suppression within the tumour microenvironment limits T cell effector function R Eil, SK Vodnala, D Clever, CA Klebanoff, M Sukumar, JH Pan, ... Nature 537 (7621), 539-543, 2016 | 596 | 2016 |
T cell stemness and dysfunction in tumors are triggered by a common mechanism SK Vodnala, R Eil, RJ Kishton, M Sukumar, TN Yamamoto, NH Ha, ... Science 363 (6434), eaau0135, 2019 | 459 | 2019 |
Mitochondrial membrane potential identifies cells with enhanced stemness for cellular therapy M Sukumar, J Liu, GU Mehta, SJ Patel, R Roychoudhuri, JG Crompton, ... Cell metabolism 23 (1), 63-76, 2016 | 372 | 2016 |
Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics JG Crompton, M Sukumar, R Roychoudhuri, D Clever, A Gros, RL Eil, ... Cancer research 75 (2), 296-305, 2015 | 365 | 2015 |
BACH2 regulates CD8+ T cell differentiation by controlling access of AP-1 factors to enhancers R Roychoudhuri, D Clever, P Li, Y Wakabayashi, KM Quinn, CA Klebanoff, ... Nature immunology 17 (7), 851-860, 2016 | 299 | 2016 |
Memory T cell–driven differentiation of naive cells impairs adoptive immunotherapy CA Klebanoff, CD Scott, AJ Leonardi, TN Yamamoto, AC Cruz, C Ouyang, ... The Journal of clinical investigation 126 (1), 318-334, 2016 | 256 | 2016 |
Oxygen sensing by T cells establishes an immunologically tolerant metastatic niche D Clever, R Roychoudhuri, MG Constantinides, MH Askenase, ... Cell 166 (5), 1117-1131. e14, 2016 | 249 | 2016 |
Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy CA Klebanoff, JG Crompton, AJ Leonardi, TN Yamamoto, SS Chandran, ... JCI insight 2 (23), 2017 | 203 | 2017 |
Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance DC Palmer, GC Guittard, Z Franco, JG Crompton, RL Eil, SJ Patel, Y Ji, ... Journal of Experimental Medicine 212 (12), 2095-2113, 2015 | 200 | 2015 |
The interplay of effector and regulatory T cells in cancer R Roychoudhuri, RL Eil, NP Restifo Current opinion in immunology 33, 101-111, 2015 | 171 | 2015 |
T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy TN Yamamoto, PH Lee, SK Vodnala, D Gurusamy, RJ Kishton, Z Yu, ... The Journal of clinical investigation 129 (4), 1551-1565, 2019 | 152 | 2019 |
Multi-phenotype CRISPR-Cas9 screen identifies p38 kinase as a target for adoptive immunotherapies D Gurusamy, AN Henning, TN Yamamoto, Z Yu, N Zacharakis, S Krishna, ... Cancer cell 37 (6), 818-833. e9, 2020 | 138 | 2020 |
Novel “elements” of immune suppression within the tumor microenvironment D Gurusamy, D Clever, R Eil, NP Restifo Cancer immunology research 5 (6), 426-433, 2017 | 67 | 2017 |
CCR8 marks highly suppressive Treg cells within tumours but is dispensable for their accumulation and suppressive function SK Whiteside, FM Grant, DS Gyori, AG Conti, CJ Imianowski, P Kuo, ... Immunology 163 (4), 512-520, 2021 | 63 | 2021 |
Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction AC Cruz, M Ramaswamy, C Ouyang, CA Klebanoff, P Sengupta, ... Nature communications 7 (1), 13895, 2016 | 63 | 2016 |
The transcription factor BACH2 promotes tumor immunosuppression R Roychoudhuri, RL Eil, D Clever, CA Klebanoff, M Sukumar, FM Grant, ... The Journal of clinical investigation 126 (2), 599-604, 2016 | 58 | 2016 |
BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression FM Grant, J Yang, R Nasrallah, J Clarke, F Sadiyah, SK Whiteside, ... Journal of Experimental Medicine 217 (9), e20190711, 2020 | 56 | 2020 |
Nomogram for predicting the benefit of neoadjuvant chemoradiotherapy for patients with esophageal cancer: A SEER‐Medicare analysis R Eil, BS Diggs, SJ Wang, JP Dolan, JG Hunter, CR Thomas Cancer 120 (4), 492-498, 2014 | 45 | 2014 |
Surgical and oncologic outcomes following repeat hepatic resection of colorectal liver metastasis: Who benefits? LH Wong, TL Sutton, BS Walker, CD Lopez, A Kardosh, RL Eil, EY Chen, ... The American Journal of Surgery 221 (6), 1114-1118, 2021 | 12 | 2021 |