| A blood RNA signature for tuberculosis disease risk: a prospective cohort study DE Zak, A Penn-Nicholson, TJ Scriba, E Thompson, S Suliman, LM Amon, ... The Lancet 387 (10035), 2312-2322, 2016 | 798 | 2016 |
| Biology of CCR5 and its role in HIV infection and treatment MM Lederman, A Penn-Nicholson, M Cho, D Mosier Jama 296 (7), 815-826, 2006 | 375 | 2006 |
| T-cell activation is an immune correlate of risk in BCG vaccinated infants HA Fletcher, MA Snowden, B Landry, W Rida, I Satti, SA Harris, ... Nature communications 7 (1), 11290, 2016 | 309 | 2016 |
| Four-gene pan-African blood signature predicts progression to tuberculosis S Suliman, EG Thompson, J Sutherland, J Weiner 3rd, MOC Ota, ... American journal of respiratory and critical care medicine 197 (9), 1198-1208, 2018 | 273 | 2018 |
| Comparing the ex vivo fitness of CCR5-tropic human immunodeficiency virus type 1 isolates of subtypes B and C SC Ball, A Abraha, KR Collins, AJ Marozsan, H Baird, ... Journal of virology 77 (2), 1021-1038, 2003 | 262 | 2003 |
| A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes R Roy Chowdhury, F Vallania, Q Yang, CJ Lopez Angel, F Darboe, ... Nature 560 (7720), 644-648, 2018 | 259 | 2018 |
| Identification of critical determinants on ACE2 for SARS-CoV entry and development of a potent entry inhibitor DP Han, A Penn-Nicholson, MW Cho Virology 350 (1), 15-25, 2006 | 242 | 2006 |
| Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease TJ Scriba, A Penn-Nicholson, S Shankar, T Hraha, EG Thompson, ... PLoS pathogens 13 (11), e1006687, 2017 | 230 | 2017 |
| Antigen availability shapes T cell differentiation and function during tuberculosis AO Moguche, M Musvosvi, A Penn-Nicholson, CR Plumlee, H Mearns, ... Cell host & microbe 21 (6), 695-706. e5, 2017 | 182 | 2017 |
| Safety and immunogenicity of the novel tuberculosis vaccine ID93+ GLA-SE in BCG-vaccinated healthy adults in South Africa: a randomised, double-blind, placebo-controlled phase … A Penn-Nicholson, M Tameris, E Smit, TA Day, M Musvosvi, ... The Lancet Respiratory Medicine 6 (4), 287-298, 2018 | 151 | 2018 |
| A complex adenovirus vaccine against chikungunya virus provides complete protection against viraemia and arthritis D Wang, A Suhrbier, A Penn-Nicholson, J Woraratanadharm, J Gardner, ... Vaccine 29 (15), 2803-2809, 2011 | 148 | 2011 |
| Live-attenuated Mycobacterium tuberculosis vaccine MTBVAC versus BCG in adults and neonates: a randomised controlled, double-blind dose-escalation trial M Tameris, H Mearns, A Penn-Nicholson, Y Gregg, N Bilek, S Mabwe, ... The lancet Respiratory medicine 7 (9), 757-770, 2019 | 130 | 2019 |
| Safety and immunogenicity of candidate vaccine M72/AS01E in adolescents in a TB endemic setting A Penn-Nicholson, H Geldenhuys, W Burny, R van der Most, CL Day, ... Vaccine 33 (32), 4025-4034, 2015 | 130 | 2015 |
| Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial TJ Scriba, A Fiore-Gartland, A Penn-Nicholson, H Mulenga, SK Mbandi, ... The Lancet Infectious Diseases 21 (3), 354-365, 2021 | 127 | 2021 |
| RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response A Penn-Nicholson, SK Mbandi, E Thompson, SC Mendelsohn, S Suliman, ... Scientific reports 10 (1), 8629, 2020 | 124 | 2020 |
| Discovery and validation of a prognostic proteomic signature for tuberculosis progression: a prospective cohort study A Penn-Nicholson, T Hraha, EG Thompson, D Sterling, SK Mbandi, ... PLoS medicine 16 (4), e1002781, 2019 | 93 | 2019 |
| Diagnostic accuracy of the Cepheid 3-gene host response fingerstick blood test in a prospective, multi-site study: interim results JS Sutherland, G van der Spuy, A Gindeh, NTT Thuong, AR Namuganga, ... Clinical Infectious Diseases 74 (12), 2136-2141, 2022 | 84 | 2022 |
| Detection of isoniazid, fluoroquinolone, ethionamide, amikacin, kanamycin, and capreomycin resistance by the Xpert MTB/XDR assay: a cross-sectional multicentre diagnostic … A Penn-Nicholson, SB Georghiou, N Ciobanu, M Kazi, M Bhalla, A David, ... The Lancet Infectious Diseases 22 (2), 242-249, 2022 | 73 | 2022 |
| Qualification of a whole blood intracellular cytokine staining assay to measure mycobacteria-specific CD4 and CD8 T cell immunity by flow cytometry BM Kagina, N Mansoor, EP Kpamegan, A Penn-Nicholson, E Nemes, ... Journal of immunological methods 417, 22-33, 2015 | 72 | 2015 |
| Safety and immunogenicity of the adjunct therapeutic vaccine ID93+ GLA-SE in adults who have completed treatment for tuberculosis: a randomised, double-blind, placebo … TA Day, A Penn-Nicholson, AKK Luabeya, A Fiore-Gartland, N Du Plessis, ... The Lancet Respiratory Medicine 9 (4), 373-386, 2021 | 66 | 2021 |
Thomas ScribaProfessor, University of Cape TownEmail verificata su uct.ac.za