DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy E Mladenov, S Magin, A Soni, G Iliakis Frontiers in oncology 3, 113, 2013 | 348 | 2013 |
DNA double-strand-break repair in higher eukaryotes and its role in genomic instability and cancer: Cell cycle and proliferation-dependent regulation E Mladenov, S Magin, A Soni, G Iliakis Seminars in cancer biology 37, 51-64, 2016 | 308 | 2016 |
Alternative end-joining repair pathways are the ultimate backup for abrogated classical non-homologous end-joining and homologous recombination repair: Implications for the … G Iliakis, T Murmann, A Soni Mutation Research/Genetic Toxicology and Environmental Mutagenesis 793, 166-175, 2015 | 235 | 2015 |
Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining A Soni, M Siemann, M Grabos, T Murmann, GE Pantelias, G Iliakis Nucleic acids research 42 (10), 6380-6392, 2014 | 124 | 2014 |
Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phase E Mladenov, X Fan, R Dueva, A Soni, G Iliakis Scientific reports 9 (1), 8255, 2019 | 66 | 2019 |
Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment A Schipler, V Mladenova, A Soni, V Nikolov, J Saha, E Mladenov, G Iliakis Nucleic acids research 44 (16), 7673-7690, 2016 | 58 | 2016 |
Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52 E Mladenov, C Staudt, A Soni, T Murmann-Konda, M Siemann-Loekes, ... Nucleic acids research 48 (4), 1905-1924, 2020 | 46 | 2020 |
DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G2-checkpoint in S-phase irradiated cells E Mladenov, X Fan, K Paul-Konietzko, A Soni, G Iliakis Scientific reports 9 (1), 14597, 2019 | 36 | 2019 |
Chromosome breaks generated by low doses of ionizing radiation in G2-phase are processed exclusively by gene conversion A Soni, T Murmann-Konda, M Siemann-Loekes, GE Pantelias, G Iliakis DNA repair 89, 102828, 2020 | 25 | 2020 |
Inhibition of Parp1 by BMN673 effectively sensitizes cells to radiotherapy by upsetting the balance of repair pathways processing DNA double-strand breaks A Soni, F Li, Y Wang, M Grabos, LM Krieger, S Chaudhary, MSM Hasan, ... Molecular cancer therapeutics 17 (10), 2206-2216, 2018 | 25 | 2018 |
The p97-Ufd1-Npl4 ATPase complex ensures robustness of the G2/M checkpoint by facilitating CDC25A degradation A Riemer, G Dobrynin, A Dressler, S Bremer, A Soni, G Iliakis, H Meyer Cell Cycle 13 (6), 919-927, 2014 | 25 | 2014 |
Marked contribution of alternative end-joining to chromosome-translocation-formation by stochastically induced DNA double-strand-breaks in G2-phase human cells A Soni, M Siemann, GE Pantelias, G Iliakis Mutation Research/Genetic Toxicology and Environmental Mutagenesis 793, 2-8, 2015 | 23 | 2015 |
Analysis of chromatid-break-repair detects a homologous recombination to non-homologous end-joining switch with increasing load of DNA double-strand breaks T Murmann-Konda, A Soni, M Stuschke, G Iliakis Mutation Research/Genetic Toxicology and Environmental Mutagenesis 867, 503372, 2021 | 21 | 2021 |
Defined biological models of high-let radiation lesions G Iliakis, V Mladenova, M Sharif, S Chaudhary, IV Mavragani, A Soni, ... Radiation protection dosimetry 183 (1-2), 60-68, 2019 | 19 | 2019 |
DNA double-strand break repair as determinant of cellular radiosensitivity to killing and target in radiation therapy. Front Oncol. 2013; 3: 113 E Mladenov, S Magin, A Soni, G Iliakis Interesting overview of the importance of DNA double-strand break repair in …, 2013 | 15 | 2013 |
Proficiency in homologous recombination repair is prerequisite for activation of G2-checkpoint at low radiation doses A Soni, E Mladenov, G Iliakis DNA repair 101, 103076, 2021 | 14 | 2021 |
Marked cell cycle-dependent contribution of alternative end joining to formation of chromosome translocations by stochastically induced DNA double strand breaks in human cells A Soni, M Siemann, GE Pantelias, G Iliakis Mutat. Res 793, 2-8, 2015 | 14 | 2015 |
Deregulated BCL-2 family proteins impact on repair of DNA double-strand breaks and are targets to overcome radioresistance in lung cancer SA Wieczorek, F Breitenbuecher, A Soni, K Paul-Konietzko, S Ziegler, ... Journal of Cancer Research and Clinical Oncology 143, 1733-1744, 2017 | 11 | 2017 |
PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination X Pei, E Mladenov, A Soni, F Li, M Stuschke, G Iliakis International journal of molecular sciences 23 (21), 12876, 2022 | 9 | 2022 |
A method for the cell-cycle-specific analysis of radiation-induced chromosome aberrations and breaks A Soni, T Murmann-Konda, S Magin, G Iliakis Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 815, 10-19, 2019 | 7 | 2019 |