CRISPR–Cas9 structures and mechanisms F Jiang, JA Doudna Annual review of biophysics 46 (1), 505-529, 2017 | 2216 | 2017 |
Structures of Cas9 endonucleases reveal RNA-mediated conformational activation M Jinek, F Jiang, DW Taylor, SH Sternberg, E Kaya, E Ma, C Anders, ... Science 343 (6176), 1247997, 2014 | 1606 | 2014 |
Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA T Saito, DM Owen, F Jiang, J Marcotrigiano, M Gale Jr Nature 454 (7203), 523-527, 2008 | 935 | 2008 |
Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair K Lee, M Conboy, HM Park, F Jiang, HJ Kim, MA Dewitt, VA Mackley, ... Nature biomedical engineering 1 (11), 889-901, 2017 | 753 | 2017 |
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage F Jiang, DW Taylor, JS Chen, JE Kornfeld, K Zhou, AJ Thompson, ... Science 351 (6275), 867-871, 2016 | 715 | 2016 |
A Cas9–guide RNA complex preorganized for target DNA recognition F Jiang, K Zhou, L Ma, S Gressel, JA Doudna Science 348 (6242), 1477-1481, 2015 | 652 | 2015 |
Structural basis of RNA recognition and activation by innate immune receptor RIG-I F Jiang, A Ramanathan, MT Miller, GQ Tang, M Gale, SS Patel, ... Nature 479 (7373), 423-427, 2011 | 505 | 2011 |
Disabling Cas9 by an anti-CRISPR DNA mimic JS Fuguo Jiang, Jun-Jie Liu, Nicolas L. Bray, Benjamin J. Rauch, Seung Hyun ... Science Advances 3 (no. 7, e1701620), DOI: 10.1126/sciadv.1701620, 2017 | 372* | 2017 |
Structural basis for m7G recognition and 2′-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I SC Devarkar, C Wang, MT Miller, A Ramanathan, F Jiang, AG Khan, ... Proceedings of the National Academy of Sciences 113 (3), 596-601, 2016 | 342 | 2016 |
The structural biology of CRISPR-Cas systems F Jiang, JA Doudna Current opinion in structural biology 30, 100-111, 2015 | 248 | 2015 |
Nucleosome breathing and remodeling constrain CRISPR-Cas9 function RS Isaac, F Jiang, JA Doudna, WA Lim, GJ Narlikar, R Almeida Elife 5, e13450, 2016 | 239 | 2016 |
Protective humoral responses to severe acute respiratory syndrome-associated coronavirus: implications for the design of an effective protein-based vaccine H Pang, Y Liu, X Han, Y Xu, F Jiang, D Wu, X Kong, M Bartlam, Z Rao Journal of general virology 85 (10), 3109-3113, 2004 | 108 | 2004 |
Extension of the crRNA enhances Cpf1 gene editing in vitro and in vivo HM Park, H Liu, J Wu, A Chong, V Mackley, C Fellmann, A Rao, F Jiang, ... Nature communications 9 (1), 3313, 2018 | 94 | 2018 |
Temperature-responsive competitive inhibition of CRISPR-Cas9 F Jiang, JJ Liu, BA Osuna, M Xu, JD Berry, BJ Rauch, E Nogales, ... Molecular cell 73 (3), 601-610. e5, 2019 | 78 | 2019 |
Regulation of retinoic acid inducible Gene-I (RIG-I) activation by the histone deacetylase 6 HM Liu, F Jiang, YM Loo, SZ Hsu, TY Hsiang, J Marcotrigiano, M Gale EBioMedicine, 2016 | 73 | 2016 |
Structure of human spindlin1: tandem Tudor-like domains for cell cycle regulation Q Zhao, L Qin, F Jiang, B Wu, W Yue, F Xu, Z Rong, H Yuan, X Xie, Y Gao, ... Journal of Biological Chemistry 282 (1), 647-656, 2007 | 71 | 2007 |
Cas9 crystals and methods of use thereof JA Doudna, SH Sternberg, M Jinek, F Jiang, E Kaya, DW Taylor Jr US Patent 9,963,689, 2018 | 46 | 2018 |
The autoinhibitory CARD2-Hel2i Interface of RIG-I governs RNA selection A Ramanathan, SC Devarkar, F Jiang, MT Miller, AG Khan, ... Nucleic acids research 44 (2), 896-909, 2016 | 42 | 2016 |
Rapid genotypic antibiotic susceptibility test using CRISPR-Cas12a for urinary tract infection J Chen, F Jiang, CW Huang, L Lin Analyst 145 (15), 5226-5231, 2020 | 16 | 2020 |
Expression, purification, crystallization and preliminary X-ray analysis of human spindlin1, an ovarian cancer-related protein F Jiang, Q Zhao, L Qin, H Pang, X Pei, Z Rao Protein and Peptide Letters 13 (2), 203-205, 2006 | 16 | 2006 |