| Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity D Shin, R Mukherjee, D Grewe, D Bojkova, K Baek, A Bhattacharya, ... Nature 587 (7835), 657-662, 2020 | 1029 | 2020 |
| OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis TET Mevissen, MK Hospenthal, PP Geurink, PR Elliott, M Akutsu, ... Cell 154 (1), 169-184, 2013 | 619 | 2013 |
| Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2 T Klemm, G Ebert, DJ Calleja, CC Allison, LW Richardson, JP Bernardini, ... The EMBO journal 39 (18), e106275, 2020 | 438 | 2020 |
| On terminal alkynes that can react with active-site cysteine nucleophiles in proteases R Ekkebus, SI van Kasteren, Y Kulathu, A Scholten, I Berlin, PP Geurink, ... Journal of the American Chemical Society 135 (8), 2867-2870, 2013 | 364 | 2013 |
| Rapid covalent-probe discovery by electrophile-fragment screening E Resnick, A Bradley, J Gan, A Douangamath, T Krojer, R Sethi, ... Journal of the American Chemical Society 141 (22), 8951-8968, 2019 | 276 | 2019 |
| The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types AC Faesen, MPA Luna-Vargas, PP Geurink, M Clerici, R Merkx, ... Chemistry & biology 18 (12), 1550-1561, 2011 | 238 | 2011 |
| Photoaffinity labeling in activity-based protein profiling PP Geurink, LM Prely, GA van der Marel, R Bischoff, HS Overkleeft Activity-based protein profiling, 85-113, 2012 | 161 | 2012 |
| Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne TET Mevissen, Y Kulathu, MPC Mulder, PP Geurink, SL Maslen, M Gersch, ... Nature 538 (7625), 402-405, 2016 | 159 | 2016 |
| The molecular basis for ubiquitin and ubiquitin-like specificities in bacterial effector proteases JN Pruneda, CH Durkin, PP Geurink, H Ovaa, B Santhanam, DW Holden, ... Molecular cell 63 (2), 261-276, 2016 | 154 | 2016 |
| Deubiquitinase activity profiling identifies UCHL1 as a candidate oncoprotein that promotes TGFβ-induced breast cancer metastasis S Liu, R González-Prieto, M Zhang, PP Geurink, R Kooij, PV Iyengar, ... Clinical Cancer Research 26 (6), 1460-1473, 2020 | 125 | 2020 |
| Structural basis of the specificity of USP18 toward ISG15 A Basters, PP Geurink, A Röcker, KF Witting, R Tadayon, S Hess, ... Nature structural & molecular biology 24 (3), 270-278, 2017 | 124 | 2017 |
| Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit β5t BI Florea, M Verdoes, N Li, WA van der Linden, PP Geurink, ... Chemistry & biology 17 (8), 795-801, 2010 | 119 | 2010 |
| Non-hydrolyzable diubiquitin probes reveal linkage-specific reactivity of deubiquitylating enzymes mediated by S2 pockets D Flierman, R Ekkebus, PP Geurink, TET Mevissen, MK Hospenthal, ... Cell chemical biology 23 (4), 472-482, 2016 | 115 | 2016 |
| A general chemical ligation approach towards isopeptide-linked ubiquitin and ubiquitin-like assay reagents PP Geurink, A Jonker, DS Hameed, H Ovaa ChemBioChem 13 (2), 293, 2012 | 110 | 2012 |
| Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites PP Geurink, WA van der Linden, AC Mirabella, N Gallastegui, G de Bruin, ... Journal of medicinal chemistry 56 (3), 1262-1275, 2013 | 109 | 2013 |
| Nature of pharmacophore influences active site specificity of proteasome inhibitors M Screen, M Britton, SL Downey, M Verdoes, MJ Voges, AEM Blom, ... Journal of Biological Chemistry 285 (51), 40125-40134, 2010 | 75 | 2010 |
| Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies KN Swatek, M Aumayr, JN Pruneda, LJ Visser, S Berryman, AF Kueck, ... Proceedings of the National Academy of Sciences 115 (10), 2371-2376, 2018 | 74 | 2018 |
| A fluorescence polarization activity-based protein profiling assay in the discovery of potent, selective inhibitors for human nonlysosomal glucosylceramidase D Lahav, B Liu, RJ van den Berg, AMCH van den Nieuwendijk, ... Journal of the American Chemical Society 139 (40), 14192-14197, 2017 | 72 | 2017 |
| Molecular characterization of ubiquitin‐specific protease 18 reveals substrate specificity for interferon‐stimulated gene 15 A Basters, PP Geurink, F El Oualid, L Ketscher, MS Casutt, E Krause, ... The FEBS journal 281 (7), 1918-1928, 2014 | 68 | 2014 |
| A cleavable linker based on the levulinoyl ester for activity-based protein profiling PP Geurink, BI Florea, N Li, MD Witte, J Verasdonck, CL Kuo, ... Angewandte Chemie International Edition 49 (38), 6802-6805, 2010 | 64 | 2010 |
