Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A J Aramburu, MB Yaffe, C López-Rodrı́guez, LC Cantley, PG Hogan, ... Science 285 (5436), 2129-2133, 1999 | 762 | 1999 |
Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity H Okamura, J Aramburu, C García-Rodríguez, JPB Viola, A Raghavan, ... Molecular cell 6 (3), 539-550, 2000 | 616 | 2000 |
NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun C López-Rodríguez, J Aramburu, AS Rakeman, A Rao Proceedings of the National Academy of Sciences 96 (13), 7214-7219, 1999 | 481 | 1999 |
Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT J Aramburu, F García-Cózar, A Raghavan, H Okamura, A Rao, PG Hogan Molecular cell 1 (5), 627-637, 1998 | 409 | 1998 |
Calcineurin: from structure to function J Aramburu, A Rao, CB Klee Current topics in cellular regulation 36, 237-295, 2001 | 391 | 2001 |
Manipulating immune responses with immunosuppressive agents that target NFAT A Kiani, A Rao, J Aramburu Immunity 12 (4), 359-372, 2000 | 373 | 2000 |
Transgenic expression of green fluorescence protein can cause dilated cardiomyopathy WY Huang, J Aramburu, PS Douglas, S Izumo Nature medicine 6 (5), 482-483, 2000 | 351 | 2000 |
Transient cardiac expression of constitutively active Gαq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways U Mende, A Kagen, A Cohen, J Aramburu, FJ Schoen, EJ Neer Proceedings of the National Academy of Sciences 95 (23), 13893-13898, 1998 | 328 | 1998 |
Bridging the NFAT and NF-κB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress C López-Rodrı́guez, J Aramburu, L Jin, AS Rakeman, M Michino, A Rao Immunity 15 (1), 47-58, 2001 | 317 | 2001 |
Interaction of calcineurin with a domain of the transcription factor NFAT1 that controls nuclear import. C Luo, KT Shaw, A Raghavan, J Aramburu, F Garcia-Cozar, BA Perrino, ... Proceedings of the National Academy of Sciences 93 (17), 8907-8912, 1996 | 244 | 1996 |
Calcineurin: a central controller of signalling in eukaryotes: Workshop on the calcium/calcineurin/nfat pathway: Regulation and function J Aramburu, J Heitman, GR Crabtree EMBO reports 5 (4), 343-348, 2004 | 210 | 2004 |
Selective inhibition of calcineurin-NFAT signaling by blocking protein–protein interaction with small organic molecules MHA Roehrl, S Kang, J Aramburu, G Wagner, A Rao, PG Hogan Proceedings of the National Academy of Sciences 101 (20), 7554-7559, 2004 | 196 | 2004 |
Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5 M Buxadé, G Lunazzi, J Minguillón, S Iborra, R Berga-Bolaños, M Del Val, ... Journal of Experimental Medicine 209 (2), 379-393, 2012 | 183 | 2012 |
Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: regulation upon CD16 ligand binding. J Aramburu, L Azzoni, A Rao, B Perussia The Journal of experimental medicine 182 (3), 801-810, 1995 | 171 | 1995 |
A novel functional cell surface dimer (Kp43) expressed by natural killer cells and T cell receptor-gamma/delta+ T lymphocytes. I. Inhibition of the IL-2-dependent proliferation … J Aramburu, MA Balboa, A Ramirez, A Silva, A Acevedo, ... Journal of immunology (Baltimore, Md.: 1950) 144 (8), 3238-3247, 1990 | 171 | 1990 |
Regulation of the hypertonic stress response and other cellular functions by the Rel-like transcription factor NFAT5 J Aramburu, K Drews-Elger, A Estrada-Gelonch, J Minguillón, ... Biochemical pharmacology 72 (11), 1597-1604, 2006 | 170 | 2006 |
Two-site interaction of nuclear factor of activated T cells with activated calcineurin FJ Garcia-Cozar, H Okamura, JF Aramburu, KTY Shaw, L Pelletier, ... Journal of Biological Chemistry 273 (37), 23877-23883, 1998 | 156 | 1998 |
Functional ambivalence of the Kp43 (CD94) NK cell-associated surface antigen. JJ Perez-Villar, I Melero, A Rodriguez, M Carretero, J Aramburu, S Sivori, ... Journal of immunology (Baltimore, Md.: 1950) 154 (11), 5779-5788, 1995 | 151 | 1995 |
The hepatitis B virus X protein induces HIV-1 replication and transcription in synergy with T-cell activation signals: functional roles of NF-κB/NF-AT and SP1-binding sites in … M Gomez-Gonzalo, M Carretero, J Rullas, E Lara-Pezzi, J Aramburu, ... Journal of Biological Chemistry 276 (38), 35435-35443, 2001 | 142 | 2001 |
Transcriptional regulation of the stress response by mTOR J Aramburu, MC Ortells, S Tejedor, M Buxadé, C López-Rodríguez Science signaling 7 (332), re2-re2, 2014 | 102 | 2014 |