| Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. N Bhala, J Emberson, A Merhi, S Abramson, N Arber, JA Baron, ... Lancet (London, England) 382 (9894), 769-779, 2013 | 1675 | 2013 |
| Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects P Patrignani, P Filabozzi, C Patrono The Journal of clinical investigation 69 (6), 1366-1372, 1982 | 1155 | 1982 |
| Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases. P Patrignani, MR Panara, A Greco, O Fusco, C Natoli, S Iacobelli, ... Journal of Pharmacology and Experimental Therapeutics 271 (3), 1705-1712, 1994 | 647 | 1994 |
| New insights into the use of currently available non-steroidal anti-inflammatory drugs K Brune, P Patrignani Journal of pain research, 105-118, 2015 | 598 | 2015 |
| Clinical pharmacology of platelet cyclooxygenase inhibition. C Patrono, G Ciabattoni, P Patrignani, F Pugliese, P Filabozzi, F Catella, ... Circulation 72 (6), 1177-1184, 1985 | 579 | 1985 |
| Advances in NSAID development: evolution of diclofenac products using pharmaceutical technology R Altman, B Bosch, K Brune, P Patrignani, C Young Drugs 75, 859-877, 2015 | 550 | 2015 |
| Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects ML Capone, MG Sciulli, S Tacconelli, M Grana, E Ricciotti, G Renda, ... Journal of the American College of Cardiology 45 (8), 1295-1301, 2005 | 381 | 2005 |
| Role of dose potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population LA García Rodríguez, S Tacconelli, P Patrignani Journal of the American College of Cardiology 52 (20), 1628-1636, 2008 | 379 | 2008 |
| Cyclooxygenase-selective inhibition of prostanoid formation: transducing biochemical selectivity into clinical read-outs C Patrono, P Patrignani, LAG Rodríguez The Journal of clinical investigation 108 (1), 7-13, 2001 | 371 | 2001 |
| Variability among nonsteroidal antiinflammatory drugs in risk of upper gastrointestinal bleeding EL Masso Gonzalez, P Patrignani, S Tacconelli, LAG Rodríguez Arthritis & Rheumatism 62 (6), 1592-1601, 2010 | 351 | 2010 |
| Oxidant stress and aspirin-insensitive thromboxane biosynthesis in severe unstable angina F Cipollone, G Ciabattoni, P Patrignani, M Pasquale, D Di Gregorio, ... Circulation 102 (9), 1007-1013, 2000 | 349 | 2000 |
| Aspirin and cancer P Patrignani, C Patrono Journal of the American College of Cardiology 68 (9), 967-976, 2016 | 301 | 2016 |
| Pharmacodynamic of cyclooxygenase inhibitors in humans ML Capone, S Tacconelli, L Di Francesco, A Sacchetti, MG Sciulli, ... Prostaglandins & other lipid mediators 82 (1-4), 85-94, 2007 | 272 | 2007 |
| Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease P Minuz, P Patrignani, S Gaino, M Degan, L Menapace, R Tommasoli, ... Circulation 106 (22), 2800-2805, 2002 | 272 | 2002 |
| Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects ML Capone, S Tacconelli, MG Sciulli, M Grana, E Ricciotti, P Minuz, ... Circulation 109 (12), 1468-1471, 2004 | 270 | 2004 |
| Cyclooxygenase inhibitors: from pharmacology to clinical read-outs P Patrignani, C Patrono Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 259 | 2015 |
| Evidence for a direct stimulatory effect of prostacyclin on renin release in man C Patrono, F Pugliese, G Ciabattoni, P Patrignani The Journal of Clinical Investigation 69 (1), 231-239, 1982 | 257 | 1982 |
| Differential suppression of thromboxane biosynthesis by indobufen and aspirin in patients with unstable angina F Cipollone, P Patrignani, A Greco, MR Panara, R Padovano, ... Circulation 96 (4), 1109-1116, 1997 | 252 | 1997 |
| Differential inhibition of human prostaglandin endoperoxide synthase-1 and-2 by nonsteroidal anti-inflammatory drugs P Patrignani, MR Panara, MG Sciulli, G Santini, G Renda, C Patrono Journal of Physiology and Pharmacology 48 (4), 1997 | 214 | 1997 |
| Reduced platelet thromboxane formation in uremia. Evidence for a functional cyclooxygenase defect G Remuzzi, A Benigni, P Dodesini, A Schieppati, M Livio, G De Gaetano, ... The Journal of clinical investigation 71 (3), 762-768, 1983 | 210 | 1983 |