Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13561* | 2021 |
Peroxisome proliferator-activated receptor α negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-κB and AP-1 P Delerive, K De Bosscher, S Besnard, WV Berghe, JM Peters, ... Journal of Biological Chemistry 274 (45), 32048-32054, 1999 | 1395 | 1999 |
The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: molecular mechanisms for gene repression K De Bosscher, W Vanden Berghe, G Haegeman Endocrine reviews 24 (4), 488-522, 2003 | 1207 | 2003 |
p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor WV Berghe, S Plaisance, E Boone, K De Bosscher, ML Schmitz, W Fiers, ... Journal of Biological Chemistry 273 (6), 3285-3290, 1998 | 830 | 1998 |
Molecular Actions of PPARα in Lipid Metabolism and Inflammation N Bougarne, B Weyers, SJ Desmet, J Deckers, DW Ray, B Staels, ... Endocrine reviews 39 (5), 760-802, 2018 | 631 | 2018 |
Therapeutic mechanisms of glucocorticoids J Vandewalle, A Luypaert, K De Bosscher, C Libert Trends in Endocrinology & Metabolism 29 (1), 42-54, 2018 | 484 | 2018 |
How glucocorticoid receptors modulate the activity of other transcription factors: a scope beyond tethering D Ratman, WV Berghe, L Dejager, C Libert, J Tavernier, IM Beck, ... Molecular and cellular endocrinology 380 (1-2), 41-54, 2013 | 472 | 2013 |
Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation K De Bosscher, ML Schmitz, W Vanden Berghe, S Plaisance, W Fiers, ... Proceedings of the National Academy of Sciences 94 (25), 13504-13509, 1997 | 467 | 1997 |
Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell K De Bosscher, W Vanden Berghe, L Vermeulen, S Plaisance, E Boone, ... Proceedings of the National Academy of Sciences 97 (8), 3919-3924, 2000 | 437 | 2000 |
The nuclear factor-κB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter WV Berghe, K De Bosscher, E Boone, S Plaisance, G Haegeman Journal of Biological Chemistry 274 (45), 32091-32098, 1999 | 430 | 1999 |
Signal transduction by tumor necrosis factor and gene regulation of the inflammatory cytokine interleukin-6 WV Berghe, L Vermeulen, G De Wilde, K De Bosscher, E Boone, ... Biochemical pharmacology 60 (8), 1185-1195, 2000 | 400 | 2000 |
Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors K De Bosscher, WV Berghe, G Haegeman Journal of neuroimmunology 109 (1), 16-22, 2000 | 395 | 2000 |
Minireview: latest perspectives on antiinflammatory actions of glucocorticoids K De Bosscher, G Haegeman Molecular endocrinology 23 (3), 281-291, 2009 | 379 | 2009 |
Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases IME Beck, W Vanden Berghe, L Vermeulen, KR Yamamoto, G Haegeman, ... Endocrine reviews 30 (7), 830-882, 2009 | 358 | 2009 |
Hop (Humulus lupulus)-Derived Bitter Acids as Multipotent Bioactive Compounds M Van Cleemput, K Cattoor, K De Bosscher, G Haegeman, ... Journal of natural products 72 (6), 1220-1230, 2009 | 338 | 2009 |
Cross-talk between nuclear receptors and nuclear factor κB K De Bosscher, W Vanden Berghe, G Haegeman Oncogene 25 (51), 6868-6886, 2006 | 336 | 2006 |
A fully dissociated compound of plant origin for inflammatory gene repression K De Bosscher, WV Berghe, IME Beck, W Van Molle, N Hennuyer, ... Proceedings of the National Academy of Sciences 102 (44), 15827-15832, 2005 | 336 | 2005 |
A paradigm for gene regulation: inflammation, NF-κB and PPAR W Vanden Berghe, L Vermeulen, P Delerive, K De Bosscher, B Staels, ... Peroxisomal disorders and regulation of genes, 181-196, 2003 | 302 | 2003 |
Selective glucocorticoid receptor modulation: New directions with non-steroidal scaffolds N Sundahl, J Bridelance, C Libert, K De Bosscher, IM Beck Pharmacology & therapeutics 152, 28-41, 2015 | 251 | 2015 |
Modulation of protein–protein interactions for the development of novel therapeutics I Petta, S Lievens, C Libert, J Tavernier, K De Bosscher Molecular Therapy 24 (4), 707-718, 2016 | 216 | 2016 |