ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering T Gaj, CA Gersbach, CF Barbas Trends in biotechnology 31 (7), 397-405, 2013 | 4923 | 2013 |
Proline-catalyzed direct asymmetric aldol reactions B List, RA Lerner, CF Barbas Journal of the American Chemical Society 122 (10), 2395-2396, 2000 | 4034 | 2000 |
Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. CF Barbas 3rd, AS Kang, RA Lerner, SJ Benkovic Proceedings of the National Academy of Sciences 88 (18), 7978-7982, 1991 | 1919 | 1991 |
Enamine-based organocatalysis with proline and diamines: the development of direct catalytic asymmetric aldol, Mannich, Michael, and Diels− Alder reactions W Notz, F Tanaka, CF Barbas Accounts of chemical research 37 (8), 580-591, 2004 | 1723 | 2004 |
Amino acid catalyzed direct asymmetric aldol reactions: a bioorganic approach to catalytic asymmetric carbon− carbon bond-forming reactions K Sakthivel, W Notz, T Bui, CF Barbas Journal of the American Chemical Society 123 (22), 5260-5267, 2001 | 1543 | 2001 |
De novo computational design of retro-aldol enzymes L Jiang, EA Althoff, FR Clemente, L Doyle, D Rothlisberger, A Zanghellini, ... science 319 (5868), 1387-1391, 2008 | 1439 | 2008 |
Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody DR Burton, J Pyati, R Koduri, SJ Sharp, GB Thornton, PWHI Parren, ... Science 266 (5187), 1024-1027, 1994 | 1430 | 1994 |
Phage display: a laboratory manual CF Barbas (No Title), 2001 | 1288 | 2001 |
The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation T Holbro, RR Beerli, F Maurer, M Koziczak, CF Barbas III, NE Hynes Proceedings of the National Academy of Sciences 100 (15), 8933-8938, 2003 | 1176 | 2003 |
A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals. DR Burton, CF Barbas 3rd, MA Persson, S Koenig, RM Chanock, ... Proceedings of the National Academy of Sciences 88 (22), 10134-10137, 1991 | 977 | 1991 |
Heterodimeric receptor libraries using phagemids C Barbas, A Kang, RA Lerner US Patent 5,658,727, 1997 | 845 | 1997 |
Toward controlling gene expression at will: Specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular … RR Beerli, DJ Segal, B Dreier, CF Barbas III Proceedings of the National Academy of Sciences 95 (25), 14628-14633, 1998 | 821 | 1998 |
Organocatalytic direct asymmetric aldol reactions in water N Mase, Y Nakai, N Ohara, H Yoda, K Takabe, F Tanaka, CF Barbas Journal of the American Chemical Society 128 (3), 734-735, 2006 | 816 | 2006 |
Organocatalytic asymmetric assembly reactions: synthesis of spirooxindoles via organocascade strategies D Cheng, Y Ishihara, B Tan, CF Barbas III Acs Catalysis 4 (3), 743-762, 2014 | 783 | 2014 |
Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces. AS Kang, CF Barbas, KD Janda, SJ Benkovic, RA Lerner Proceedings of the National Academy of Sciences 88 (10), 4363-4366, 1991 | 760 | 1991 |
Engineering polydactyl zinc-finger transcription factors RR Beerli, CF Barbas III Nature biotechnology 20 (2), 135-141, 2002 | 711 | 2002 |
Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem. CF Barbas 3rd, JD Bain, DM Hoekstra, RA Lerner Proceedings of the National Academy of Sciences 89 (10), 4457-4461, 1992 | 651 | 1992 |
CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range WP Yang, K Green, S Pinz-Sweeney, AT Briones, DR Burton, ... Journal of molecular biology 254 (3), 392-403, 1995 | 632 | 1995 |
Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG A Trkola, AB Pomales, H Yuan, B Korber, PJ Maddon, GP Allaway, ... Journal of virology 69 (11), 6609-6617, 1995 | 616 | 1995 |
Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5′-GNN-3′ DNA target sequences DJ Segal, B Dreier, RR Beerli, CF Barbas III Proceedings of the National Academy of Sciences 96 (6), 2758-2763, 1999 | 608 | 1999 |