| Anti‐inflammatory and antioxidative effects of propofol on lipopolysaccharide‐activated macrophages RM CHEN, TG CHEN, TAL CHEN, LIL LIN, CC CHANG, HWAC CHANG, ... Annals of the New York Academy of Sciences 1042 (1), 262-271, 2005 | 178 | 2005 |
| The epigenetic effects of amyloid-β1–40 on global DNA and neprilysin genes in murine cerebral endothelial cells KL Chen, SSS Wang, YY Yang, RY Yuan, RM Chen, CJ Hu Biochemical and biophysical research communications 378 (1), 57-61, 2009 | 176 | 2009 |
| MicroRNA-210 targets antiapoptotic Bcl-2 expression and mediates hypoxia-induced apoptosis of neuroblastoma cells CC Chio, JW Lin, HA Cheng, WT Chiu, YH Wang, JJ Wang, CH Hsing, ... Archives of toxicology 87, 459-468, 2013 | 139 | 2013 |
| Propofol suppresses macrophage functions and modulates mitochondrial membrane potential and cellular adenosine triphosphate synthesis RM Chen, CH Wu, HC Chang, GJ Wu, YL Lin, JR Sheu, TL Chen The Journal of the American Society of Anesthesiologists 98 (5), 1178-1185, 2003 | 138 | 2003 |
| Suppressive effects of ketamine on macrophage functions Y Chang, TL Chen, JR Sheu, RM Chen Toxicology and applied pharmacology 204 (1), 27-35, 2005 | 134 | 2005 |
| Honokiol traverses the blood-brain barrier and induces apoptosis of neuroblastoma cells via an intrinsic bax-mitochondrion-cytochrome c-caspase protease pathway JW Lin, JT Chen, CY Hong, YL Lin, KT Wang, CJ Yao, GM Lai, RM Chen Neuro-oncology 14 (3), 302-314, 2012 | 131 | 2012 |
| Honokiol induces autophagy of neuroblastoma cells through activating the PI3K/Akt/mTOR and endoplasmic reticular stress/ERK1/2 signaling pathways and suppressing cell migration PS Yeh, W Wang, YA Chang, CJ Lin, JJ Wang, RM Chen Cancer letters 370 (1), 66-77, 2016 | 130 | 2016 |
| Ketamine inhibits tumor necrosis factor-α and interleukin-6 gene expressions in lipopolysaccharide-stimulated macrophages through suppression of toll-like receptor 4-mediated c … GJ Wu, TL Chen, YF Ueng, RM Chen Toxicology and Applied Pharmacology 228 (1), 105-113, 2008 | 130 | 2008 |
| Nitric oxide from both exogenous and endogenous sources activates mitochondria‐dependent events and induces insults to human chondrocytes GJ Wu, TG Chen, HC Chang, WT Chiu, CC Chang, RM Chen Journal of cellular biochemistry 101 (6), 1520-1531, 2007 | 128 | 2007 |
| Lipopolysaccharide triggers macrophage activation of inflammatory cytokine expression, chemotaxis, phagocytosis, and oxidative ability via a toll-like receptor 4-dependent … TT Wu, TL Chen, RM Chen Toxicology letters 191 (2-3), 195-202, 2009 | 117 | 2009 |
| Honokiol induces autophagic cell death in malignant glioma through reactive oxygen species-mediated regulation of the p53/PI3K/Akt/mTOR signaling pathway CJ Lin, TL Chen, YY Tseng, GJ Wu, MH Hsieh, YW Lin, RM Chen Toxicology and Applied Pharmacology 304, 59-69, 2016 | 115 | 2016 |
| Lipopolysaccharide induces apoptotic insults to human alveolar epithelial A549 cells through reactive oxygen species-mediated activation of an intrinsic mitochondrion-dependent … CY Chuang, TL Chen, YG Cherng, YT Tai, TG Chen, RM Chen Archives of toxicology 85, 209-218, 2011 | 105 | 2011 |
| Apoptotic insults to human HepG2 cells induced by S-(+)-ketamine occurs through activation of a Bax-mitochondria-caspase protease pathway ST Lee, TT Wu, PY Yu, RM Chen British journal of anaesthesia 102 (1), 80-89, 2009 | 92 | 2009 |
| Gold nanoparticles increase endothelial paracellular permeability by altering components of endothelial tight junctions, and increase blood-brain barrier permeability in mice CH Li, MK Shyu, C Jhan, YW Cheng, CH Tsai, CW Liu, CC Lee, RM Chen, ... Toxicological Sciences 148 (1), 192-203, 2015 | 91 | 2015 |
| Molecular mechanism of nitric oxide‐induced osteoblast apoptosis RM Chen, TL Chen, WT Chiu, CC Chang Journal of orthopaedic research 23 (2), 462-468, 2005 | 90 | 2005 |
| Nitric oxide modulates pro-and anti-inflammatory cytokines in lipopolysaccharide-activated macrophages CH Wu, TL Chen, TG Chen, WP Ho, WT Chiu, RM Chen Journal of Trauma and Acute Care Surgery 55 (3), 540-545, 2003 | 90 | 2003 |
| Improving effects of chitosan nanofiber scaffolds on osteoblast proliferation and maturation MH Ho, MH Liao, YL Lin, CH Lai, PI Lin, RM Chen International journal of nanomedicine, 4293-4304, 2014 | 85 | 2014 |
| Resveratrol protects against oxidized LDL-induced breakage of the blood-brain barrier by lessening disruption of tight junctions and apoptotic insults to mouse cerebrovascular … YL Lin, HC Chang, TL Chen, JH Chang, WT Chiu, JW Lin, RM Chen The Journal of nutrition 140 (12), 2187-2192, 2010 | 85 | 2010 |
| Lipoteichoic acid-induced TNF-α and IL-6 gene expressions and oxidative stress production in macrophages are suppressed by ketamine through downregulating Toll-like receptor 2 … HC Chang, KH Lin, YT Tai, JT Chen, RM Chen Shock 33 (5), 485-492, 2010 | 83 | 2010 |
| Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma WB Yang, CC Hsu, TI Hsu, JP Liou, KY Chang, PY Chen, JJ Liu, ST Yang, ... Neuro-oncology 22 (10), 1439-1451, 2020 | 80 | 2020 |