Regulatory T cells: mechanisms of differentiation and function SZ Josefowicz, LF Lu, AY Rudensky Annual review of immunology 30 (1), 531-564, 2012 | 3364 | 2012 |
Cutting edge: contact-mediated suppression by CD4+ CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism DC Gondek, LF Lu, SA Quezada, S Sakaguchi, RJ Noelle The journal of immunology 174 (4), 1783-1786, 2005 | 1396 | 2005 |
Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses LF Lu, MP Boldin, A Chaudhry, LL Lin, KD Taganov, T Hanada, ... Cell 142 (6), 914-929, 2010 | 1102 | 2010 |
Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein LF Lu, TH Thai, DP Calado, A Chaudhry, M Kubo, K Tanaka, GB Loeb, ... Immunity 30 (1), 80-91, 2009 | 1049 | 2009 |
Mast cells are essential intermediaries in regulatory T-cell tolerance LF Lu, EF Lind, DC Gondek, KA Bennett, MW Gleeson, K Pino-Lagos, ... Nature 442 (7106), 997-1002, 2006 | 914 | 2006 |
VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses L Wang, R Rubinstein, JL Lines, A Wasiuk, C Ahonen, Y Guo, LF Lu, ... Journal of Experimental Medicine 208 (3), 577-592, 2011 | 796 | 2011 |
Dicer-dependent microRNA pathway safeguards regulatory T cell function A Liston, LF Lu, D O'Carroll, A Tarakhovsky, AY Rudensky The Journal of experimental medicine 205 (9), 1993-2004, 2008 | 498 | 2008 |
In vivo target gene activation via CRISPR/Cas9-mediated trans-epigenetic modulation HK Liao, F Hatanaka, T Araoka, P Reddy, MZ Wu, Y Sui, T Yamauchi, ... Cell 171 (7), 1495-1507. e15, 2017 | 459 | 2017 |
MicroRNA in the immune system, microRNA as an immune system LF Lu, A Liston Immunology 127 (3), 291-298, 2009 | 387 | 2009 |
PD-L1: CD80 cis-heterodimer triggers the co-stimulatory receptor CD28 while repressing the inhibitory PD-1 and CTLA-4 pathways Y Zhao, CK Lee, CH Lin, RB Gassen, X Xu, Z Huang, C Xiao, C Bonorino, ... Immunity 51 (6), 1059-1073. e9, 2019 | 315 | 2019 |
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells W Pierson, B Cauwe, A Policheni, SM Schlenner, D Franckaert, J Berges, ... Nature immunology 14 (9), 959-965, 2013 | 264 | 2013 |
An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses M Mann, A Mehta, JL Zhao, K Lee, GK Marinov, Y Garcia-Flores, LF Lu, ... Nature communications 8 (1), 851, 2017 | 243 | 2017 |
Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses BS Boland, Z He, MS Tsai, JG Olvera, KD Omilusik, HG Duong, ES Kim, ... Science immunology 5 (50), eabb4432, 2020 | 183 | 2020 |
A single miRNA-mRNA interaction affects the immune response in a context-and cell-type-specific manner LF Lu, G Gasteiger, IS Yu, A Chaudhry, JP Hsin, Y Lu, PD Bos, LL Lin, ... Immunity 43 (1), 52-64, 2015 | 175 | 2015 |
Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type I interferon BC Ho, IS Yu, LF Lu, A Rudensky, HY Chen, CW Tsai, YL Chang, CT Wu, ... Nature communications 5 (1), 3344, 2014 | 160 | 2014 |
miR-23∼ 27∼ 24 clusters control effector T cell differentiation and function S Cho, CJ Wu, T Yasuda, LO Cruz, AA Khan, LL Lin, DT Nguyen, M Miller, ... Journal of Experimental Medicine 213 (2), 235-249, 2016 | 147 | 2016 |
miR-25/93 mediates hypoxia-induced immunosuppression by repressing cGAS MZ Wu, WC Cheng, SF Chen, S Nieh, C O’Connor, CL Liu, WW Tsai, ... Nature cell biology 19 (10), 1286-1296, 2017 | 132 | 2017 |
Transplantation survival is maintained by granzyme B+ regulatory cells and adaptive regulatory T cells DC Gondek, V DeVries, EC Nowak, LF Lu, KA Bennett, ZA Scott, ... The Journal of Immunology 181 (7), 4752-4760, 2008 | 131 | 2008 |
Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease M Miyazaki, K Miyazaki, S Chen, M Itoi, M Miller, LF Lu, N Varki, ... Nature immunology 15 (8), 767-776, 2014 | 126 | 2014 |
Id2 reinforces TH1 differentiation and inhibits E2A to repress TFH differentiation LA Shaw, S Bélanger, KD Omilusik, S Cho, JP Scott-Browne, JP Nance, ... Nature immunology 17 (7), 834-843, 2016 | 121 | 2016 |