Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning A Aiuti, S Slavin, M Aker, F Ficara, S Deola, A Mortellaro, S Morecki, ... Science 296 (5577), 2410-2413, 2002 | 1458 | 2002 |
Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes E Viganò, CE Diamond, R Spreafico, A Balachander, RM Sobota, ... Nature communications 6 (1), 8761, 2015 | 384 | 2015 |
Inflammasome-dependent IL-1β release depends upon membrane permeabilisation F Martín-Sánchez, C Diamond, M Zeitler, AI Gomez, A Baroja-Mazo, ... Cell Death & Differentiation 23 (7), 1219-1231, 2016 | 298 | 2016 |
Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement A Aiuti, S Vai, A Mortellaro, G Casorati, F Ficara, G Andolfi, G Ferrari, ... Nature medicine 8 (5), 423-425, 2002 | 258 | 2002 |
Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages L Tailleux, SJ Waddell, M Pelizzola, A Mortellaro, M Withers, A Tanne, ... PloS one 3 (1), e1403, 2008 | 234 | 2008 |
Cutting edge: the NLRP3 inflammasome links complement-mediated inflammation and IL-1β release F Laudisi, R Spreafico, M Evrard, TR Hughes, B Mandriani, M Kandasamy, ... The Journal of Immunology 191 (3), 1006-1010, 2013 | 222 | 2013 |
CD80 and CD86 differentially regulate mechanical interactions of T-cells with antigen-presenting dendritic cells and B-cells TS Lim, JKH Goh, A Mortellaro, CT Lim, GJ Hämmerling, ... Public Library of Science 7 (9), e45185, 2012 | 196 | 2012 |
A unique role for p53 in the regulation of M2 macrophage polarization L Li, DSW Ng, WC Mah, FF Almeida, SA Rahmat, VK Rao, SC Leow, ... Cell Death & Differentiation 22 (7), 1081-1093, 2015 | 161 | 2015 |
New immunosuppressive drug PNU156804 blocks IL-2-dependent proliferation and NF-κB and AP-1 activation A Mortellaro, S Songia, P Gnocchi, M Ferrari, C Fornasiero, R D’Alessio, ... The Journal of Immunology 162 (12), 7102-7109, 1999 | 140 | 1999 |
The NLRP3 inflammasome may contribute to pathologic neovascularization in the advanced stages of diabetic retinopathy SS Chaurasia, RR Lim, BH Parikh, YS Wey, BB Tun, TY Wong, CD Luu, ... Scientific reports 8 (1), 2847, 2018 | 137 | 2018 |
Characterization of the new immunosuppressive drug undecylprodigiosin in human lymphocytes: retinoblastoma protein, cyclin-dependent kinase-2, and cyclin-dependent kinase-4 as … S Songia, A Mortellaro, S Taverna, C Fornasiero, EA Scheiber, E Erba, ... Journal of immunology (Baltimore, Md.: 1950) 158 (8), 3987-3995, 1997 | 119 | 1997 |
Uric acid-driven Th17 differentiation requires inflammasome-derived IL-1 and IL-18 C Conforti-Andreoni, R Spreafico, HL Qian, N Riteau, B Ryffel, ... The Journal of Immunology 187 (11), 5842-5850, 2011 | 118 | 2011 |
The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond C Conforti-Andreoni, P Ricciardi-Castagnoli, A Mortellaro Cellular & molecular immunology 8 (2), 135-145, 2011 | 117 | 2011 |
The controversial relationship between NLRP3, alum, danger signals and the next‐generation adjuvants R Spreafico, P Ricciardi‐Castagnoli, A Mortellaro European journal of immunology 40 (3), 638-642, 2010 | 112 | 2010 |
Caspase‐11: the driving factor for noncanonical inflammasomes E Viganò, A Mortellaro European journal of immunology 43 (9), 2240-2245, 2013 | 100 | 2013 |
CD103+ dendritic cells control Th17 cell function in the lung T Zelante, AYW Wong, TJ Ping, J Chen, HR Sumatoh, E Viganò, YH Bing, ... Cell reports 12 (11), 1789-1801, 2015 | 96 | 2015 |
The rhapsody of NLRPs: master players of inflammation… and a lot more LP Zambetti, F Laudisi, G Licandro, P Ricciardi-Castagnoli, A Mortellaro Immunologic research 53, 78-90, 2012 | 94 | 2012 |
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)–deficient mice and corrects their immune and metabolic defects A Mortellaro, RJ Hernandez, MM Guerrini, F Carlucci, A Tabucchi, ... Blood 108 (9), 2979-2988, 2006 | 90 | 2006 |
Assessment of thymic output in common variable immunodeficiency patients by evaluation of T cell receptor excision circles V Guazzi, F Aiuti, I Mezzaroma, F Mazzetta, G Andolfi, A Mortellaro, ... Clinical & Experimental Immunology 129 (2), 346-353, 2002 | 87 | 2002 |
Update on clinical ex vivo hematopoietic stem cell gene therapy for inherited monogenic diseases F Tucci, S Scaramuzza, A Aiuti, A Mortellaro Molecular Therapy 29 (2), 489-504, 2021 | 84 | 2021 |