| Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation PR Angelova, ML Choi, AV Berezhnov, MH Horrocks, CD Hughes, S De, ... Cell Death & Differentiation 27 (10), 2781-2796, 2020 | 213 | 2020 |
| Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms S De, DC Wirthensohn, P Flagmeier, C Hughes, FA Aprile, FS Ruggeri, ... Nature communications 10 (1), 1541, 2019 | 187 | 2019 |
| Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity ML Choi, A Chappard, BP Singh, C Maclachlan, M Rodrigues, ... Nature neuroscience 25 (9), 1134-1148, 2022 | 142 | 2022 |
| Hsp70 inhibits the nucleation and elongation of tau and sequesters tau aggregates with high affinity F Kundel, S De, P Flagmeier, MH Horrocks, M Kjaergaard, SL Shammas, ... ACS chemical biology 13 (3), 636-646, 2018 | 108 | 2018 |
| Mapping surface hydrophobicity of α-synuclein oligomers at the nanoscale JE Lee, JC Sang, M Rodrigues, AR Carr, MH Horrocks, S De, ... Nano letters 18 (12), 7494-7501, 2018 | 106 | 2018 |
| Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, ... Angewandte Chemie International Edition 56 (27), 7750-7754, 2017 | 105 | 2017 |
| Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease D Emin, YP Zhang, E Lobanova, A Miller, X Li, Z Xia, H Dakin, DI Sideris, ... Nature communications 13 (1), 5512, 2022 | 104 | 2022 |
| Potential clinical applications of stem cells in regenerative medicine S Suman, A Domingues, J Ratajczak, MZ Ratajczak Stem Cells: Therapeutic Applications, 1-22, 2019 | 104 | 2019 |
| Ultranarrow and Widely Tunable Mn 2+-Induced Photoluminescence from Single Mn-Doped Nanocrystals of ZnS-CdS Alloys A Hazarika, A Layek, S De, A Nag, S Debnath, P Mahadevan, ... Physical Review Letters 110 (26), 267401, 2013 | 96 | 2013 |
| Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer’s disease progression S De, DR Whiten, FS Ruggeri, C Hughes, M Rodrigues, DI Sideris, ... Acta Neuropathologica Communications 7 (120), 1-13, 2019 | 94 | 2019 |
| Plasticization of poly (vinylpyrrolidone) thin films under ambient humidity: Insight from single-molecule tracer diffusion dynamics S Bhattacharya, DK Sharma, S Saurabh, S De, A Sain, A Nandi, ... The Journal of Physical Chemistry B 117 (25), 7771-7782, 2013 | 81 | 2013 |
| Single-molecule characterization of the interactions between extracellular chaperones and toxic α-synuclein oligomers DR Whiten, D Cox, MH Horrocks, CG Taylor, S De, P Flagmeier, L Tosatto, ... Cell reports 23 (12), 3492-3500, 2018 | 68 | 2018 |
| Quantum-confined stark effect in localized luminescent centers within InGaN/GaN quantum-well based light emitting diodes S De, A Layek, S Bhattacharya, D Kumar Das, A Kadir, A Bhattacharya, ... Applied Physics Letters 101 (12), 2012 | 59 | 2012 |
| Nanoscopic characterisation of individual endogenous protein aggregates in human neuronal cells DR Whiten, Y Zuo, L Calo, ML Choi, S De, P Flagmeier, DC Wirthensohn, ... ChemBioChem 19 (19), 2033-2038, 2018 | 58 | 2018 |
| Two Distinct Origins of Highly Localized Luminescent Centers within InGaN/GaN Quantum‐Well Light‐Emitting Diodes S De, A Layek, A Raja, A Kadir, MR Gokhale, A Bhattacharya, S Dhar, ... Advanced Functional Materials 21 (20), 3828-3835, 2011 | 58 | 2011 |
| Spectrally resolved photoluminescence imaging of ZnO nanocrystals at single-particle levels A Layek, S De, R Thorat, A Chowdhury The Journal of Physical Chemistry Letters 2 (11), 1241-1247, 2011 | 55 | 2011 |
| Quantifying co-oligomer formation by α-synuclein M Iljina, AJ Dear, GA Garcia, S De, L Tosatto, P Flagmeier, DR Whiten, ... ACS nano 12 (11), 10855-10866, 2018 | 54 | 2018 |
| Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation P Flagmeier, S De, TCT Michaels, X Yang, AJ Dear, C Emanuelsson, ... Nature Structural & Molecular Biology 27 (10), 886-891, 2020 | 52 | 2020 |
| Soluble amyloid beta-containing aggregates are present throughout the brain at early stages of Alzheimer’s disease DI Sideris, JSH Danial, D Emin, FS Ruggeri, Z Xia, YP Zhang, ... Brain communications 3 (3), fcab147, 2021 | 51 | 2021 |
| Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation A Vilalta, Y Zhou, J Sevalle, JK Griffin, K Satoh, DH Allendorf, S De, ... Journal of Biological Chemistry 296, 2021 | 48 | 2021 |
Christopher DobsonUniversity of CambridgeEmail verificata su cam.ac.uk
