Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor α expression by inducing Elk-1 phosphorylation … M Guha, MA O'Connell, R Pawlinski, A Hollis, P McGovern, SF Yan, ... Blood, The Journal of the American Society of Hematology 98 (5), 1429-1439, 2001 | 475 | 2001 |
Fruit and vegetable intakes and bone mineral status: a cross-sectional study in 5 age and sex cohorts CJ Prynne, GD Mishra, MA O’Connell, G Muniz, MA Laskey, L Yan, ... The American journal of clinical nutrition 83 (6), 1420-1428, 2006 | 340 | 2006 |
Lipopolysaccharide-induced expression of NAD (P) H: quinone oxidoreductase 1 and heme oxygenase-1 protects against excessive inflammatory responses in human monocytes SA Rushworth, DJ MacEwan, MA O'Connell The Journal of Immunology 181 (10), 6730-6737, 2008 | 255 | 2008 |
Role of IKK1 and IKK2 in lipopolysaccharide signaling in human monocytic cells MA O'Connell, BL Bennett, F Mercurio, AM Manning, N Mackman Journal of Biological Chemistry 273 (46), 30410-30414, 1998 | 225 | 1998 |
Lipopolysaccharide-induced heme oxygenase-1 expression in human monocytic cells is mediated via Nrf2 and protein kinase C SA Rushworth, XL Chen, N Mackman, RM Ogborne, MA O’Connell The Journal of Immunology 175 (7), 4408-4415, 2005 | 222 | 2005 |
Role of protein kinase C δ in curcumin-induced antioxidant response element-mediated gene expression in human monocytes SA Rushworth, RM Ogborne, CA Charalambos, MA O’Connell Biochemical and biophysical research communications 341 (4), 1007-1016, 2006 | 197 | 2006 |
The impact of long chain n‐3 polyunsaturated fatty acid supplementation on inflammation, insulin sensitivity and CVD risk in a group of overweight women with an … LM Browning, JD Krebs, CS Moore, GD Mishra, MA O’Connell, SA Jebb Diabetes, Obesity and Metabolism 9 (1), 70-80, 2007 | 196 | 2007 |
A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules J Reed, MJ Stephenson, K Miettinen, B Brouwer, A Leveau, P Brett, ... Metabolic Engineering 42, 185-193, 2017 | 187 | 2017 |
The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic MA O’Connell, JD Hayes Biochemical Society Transactions 43 (4), 687-689, 2015 | 172 | 2015 |
Extracellular signal–regulated kinase 1/extracellular signal–regulated kinase 2 mitogen‐activated protein kinase signaling and activation of activator protein 1 and nuclear … R Liu, M O'Connell, K Johnson, K Pritzker, N Mackman, R Terkeltaub Arthritis & Rheumatism: Official Journal of the American College of …, 2000 | 139 | 2000 |
Anti-inflammatory effect of a cell-penetrating peptide targeting the Nrf2/Keap1 interaction R Steel, J Cowan, E Payerne, MA O'Connell, M Searcey ACS medicinal chemistry letters 3 (5), 407-410, 2012 | 136 | 2012 |
α-lipoic acid–induced heme oxygenase-1 expression is mediated by nuclear factor erythroid 2-related factor 2 and p38 mitogen-activated protein kinase in human monocytic cells RM Ogborne, SA Rushworth, MA O’Connell Arteriosclerosis, thrombosis, and vascular biology 25 (10), 2100-2105, 2005 | 125 | 2005 |
Flavonoid metabolites reduce tumor necrosis factor‐α secretion to a greater extent than their precursor compounds in human THP‐1 monocytes JL di Gesso, JS Kerr, Q Zhang, S Raheem, SK Yalamanchili, D O'Hagan, ... Molecular nutrition & food research 59 (6), 1143-1154, 2015 | 113 | 2015 |
Curcumin: potential for hepatic fibrosis therapy? MA O'Connell, SA Rushworth British journal of pharmacology 153 (3), 403-405, 2008 | 100 | 2008 |
Common phenolic metabolites of flavonoids, but not their unmetabolized precursors, reduce the secretion of vascular cellular adhesion molecules by human endothelial cells EF Warner, Q Zhang, KS Raheem, D O’Hagan, MA O’Connell, CD Kay The Journal of nutrition 146 (3), 465-473, 2016 | 99 | 2016 |
Moderate alcohol consumption and increased bone mineral density: potential ethanol and non-ethanol mechanisms R Jugdaohsingh, MA O'connell, S Sripanyakorn, JJ Powell Proceedings of the Nutrition Society 65 (3), 291-310, 2006 | 85 | 2006 |
Microalbuminuria in inflammatory bowel disease. N Mahmud, J Stinson, MA O'Connell, TJ Mantle, PW Keeling, J Feely, ... Gut 35 (11), 1599-1604, 1994 | 85 | 1994 |
Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2-2 genotype SH Atkinson, K Rockett, G Sirugo, PA Bejon, A Fulford, MA O'Connell, ... PLoS medicine 3 (5), e172, 2006 | 84 | 2006 |
Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase M Tortorici, MT Borrello, M Tardugno, LR Chiarelli, S Pilotto, G Ciossani, ... ACS chemical biology 8 (8), 1677-1682, 2013 | 83 | 2013 |
Cellular Proliferation and Activation of NFκB Are Induced by Autocrine Production of Tumor Necrosis Factor α in the Human T Lymphoma Line HuT 78 (∗) MA O'Connell, R Cleere, A Long, LAJ O'Neill, D Kelleher Journal of Biological Chemistry 270 (13), 7399-7404, 1995 | 78 | 1995 |