Tumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients treated with neoadjuvant therapy C Denkert, G von Minckwitz, S Darb-Esfahani, B Lederer, BI Heppner, ... The lancet oncology 19 (1), 40-50, 2018 | 1849 | 2018 |
Recommendations from an international consensus conference on the current status and future of neoadjuvant systemic therapy in primary breast cancer M Kaufmann, G Von Minckwitz, EP Mamounas, D Cameron, LA Carey, ... Annals of surgical oncology 19, 1508-1516, 2012 | 584 | 2012 |
T-cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers A Rody, U Holtrich, L Pusztai, C Liedtke, R Gaetje, E Ruckhaeberle, ... Breast Cancer Research 11, 1-13, 2009 | 454 | 2009 |
Germline mutation status, pathological complete response, and disease-free survival in triple-negative breast cancer: secondary analysis of the GeparSixto randomized clinical trial E Hahnen, B Lederer, J Hauke, S Loibl, S Kröber, A Schneeweiss, ... JAMA oncology 3 (10), 1378-1385, 2017 | 425 | 2017 |
A clinically relevant gene signature in triple negative and basal-like breast cancer A Rody, T Karn, C Liedtke, L Pusztai, E Ruckhaeberle, L Hanker, R Gaetje, ... Breast cancer research 13, 1-12, 2011 | 385 | 2011 |
Induction and down-regulation of PLK, a human serine/threonine kinase expressed in proliferating cells and tumors. UWE Holtrich, G Wolf, A Bräuninger, T Karn, B Böhme, ... Proceedings of the National Academy of Sciences 91 (5), 1736-1740, 1994 | 368 | 1994 |
Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer E Ruckhäberle, A Rody, K Engels, R Gaetje, G Von Minckwitz, ... Breast cancer research and treatment 112, 41-52, 2008 | 362 | 2008 |
PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor B Hock, B Böhme, T Karn, T Yamamoto, K Kaibuchi, U Holtrich, S Holland, ... Proceedings of the National Academy of Sciences 95 (17), 9779-9784, 1998 | 280 | 1998 |
A comprehensive analysis of human gene expression profiles identifies stromal immunoglobulin κ C as a compatible prognostic marker in human solid tumors M Schmidt, B Hellwig, S Hammad, A Othman, M Lohr, Z Chen, D Boehm, ... Clinical cancer research 18 (9), 2695-2703, 2012 | 268 | 2012 |
CD73 is associated with poor prognosis in high-grade serous ovarian cancer M Turcotte, K Spring, S Pommey, G Chouinard, I Cousineau, J George, ... Cancer research 75 (21), 4494-4503, 2015 | 238 | 2015 |
Identification of high risk breast-cancer patients by gene expression profiling A Ahr, T Karn, C Solbach, T Seiter, K Strebhardt, U Holtrich, M Kaufmann The Lancet 359 (9301), 131-132, 2002 | 230 | 2002 |
Ki67 measured after neoadjuvant chemotherapy for primary breast cancer G Von Minckwitz, WD Schmitt, S Loibl, BM Müller, JU Blohmer, BV Sinn, ... Clinical cancer research 19 (16), 4521-4531, 2013 | 182 | 2013 |
Tumor mutational burden and immune infiltration as independent predictors of response to neoadjuvant immune checkpoint inhibition in early TNBC in GeparNuevo T Karn, C Denkert, KE Weber, U Holtrich, C Hanusch, BV Sinn, BW Higgs, ... Annals of Oncology 31 (9), 1216-1222, 2020 | 176 | 2020 |
Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial I Stevic, V Müller, K Weber, PA Fasching, T Karn, F Marmé, C Schem, ... BMC medicine 16, 1-16, 2018 | 163 | 2018 |
Association between genomic metrics and immune infiltration in triple-negative breast cancer T Karn, T Jiang, C Hatzis, N Sänger, A El-Balat, A Rody, U Holtrich, ... JAMA oncology 3 (12), 1707-1711, 2017 | 160 | 2017 |
New strategies in breast cancer: immunotherapy L Pusztai, T Karn, A Safonov, MM Abu-Khalaf, G Bianchini Clinical Cancer Research 22 (9), 2105-2110, 2016 | 155 | 2016 |
Immune gene expression is associated with genomic aberrations in breast cancer A Safonov, T Jiang, G Bianchini, B Győrffy, T Karn, C Hatzis, L Pusztai Cancer research 77 (12), 3317-3324, 2017 | 144 | 2017 |
Gene expression of ceramide kinase, galactosyl ceramide synthase and ganglioside GD3 synthase is associated with prognosis in breast cancer E Ruckhäberle, T Karn, A Rody, L Hanker, R Gätje, D Metzler, U Holtrich, ... Journal of cancer research and clinical oncology 135, 1005-1013, 2009 | 119 | 2009 |
The prognostic impact of age in different molecular subtypes of breast cancer C Liedtke, A Rody, O Gluz, K Baumann, D Beyer, EB Kohls, K Lausen, ... Breast cancer research and treatment 152, 667-673, 2015 | 117 | 2015 |
Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosis N Verma, Y Vinik, A Saroha, NU Nair, E Ruppin, G Mills, T Karn, V Dubey, ... Science advances 6 (34), eaba8968, 2020 | 116 | 2020 |