PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 S Geisler, KM Holmström, D Skujat, FC Fiesel, OC Rothfuss, PJ Kahle, ... Nature cell biology 12 (2), 119-131, 2010 | 3190 | 2010 |
Cellular mechanisms and physiological consequences of redox-dependent signalling KM Holmström, T Finkel Nature reviews Molecular cell biology 15 (6), 411-421, 2014 | 2290 | 2014 |
Measuring in vivo mitophagy N Sun, J Yun, J Liu, D Malide, C Liu, II Rovira, KM Holmström, ... Molecular cell 60 (4), 685-696, 2015 | 680 | 2015 |
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin N Exner, B Treske, D Paquet, K Holmström, C Schiesling, S Gispert, ... Journal of Neuroscience 27 (45), 12413-12418, 2007 | 655 | 2007 |
Nrf2 regulates ROS production by mitochondria and NADPH oxidase S Kovac, PR Angelova, KM Holmström, Y Zhang, AT Dinkova-Kostova, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (4), 794-801, 2015 | 643 | 2015 |
Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration KM Holmström, L Baird, Y Zhang, I Hargreaves, A Chalasani, JM Land, ... Biology open 2 (8), 761-770, 2013 | 478 | 2013 |
The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations S Geisler, KM Holmström, A Treis, D Skujat, SS Weber, FC Fiesel, ... Autophagy 6 (7), 871-878, 2010 | 389 | 2010 |
The multifaceted role of Nrf2 in mitochondrial function KM Holmström, RV Kostov, AT Dinkova-Kostova Current opinion in toxicology 1, 80-91, 2016 | 380 | 2016 |
The ins and outs of mitochondrial calcium T Finkel, S Menazza, KM Holmström, RJ Parks, J Liu, J Sun, J Liu, X Pan, ... Circulation research 116 (11), 1810-1819, 2015 | 311 | 2015 |
Mutations in ANO3 cause dominant craniocervical dystonia: ion channel implicated in pathogenesis G Charlesworth, V Plagnol, KM Holmström, J Bras, UM Sheerin, E Preza, ... The American Journal of Human Genetics 91 (6), 1041-1050, 2012 | 307 | 2012 |
MICU1 serves as a molecular gatekeeper to prevent in vivo mitochondrial calcium overload JC Liu, J Liu, KM Holmström, S Menazza, RJ Parks, MM Fergusson, ... Cell reports 16 (6), 1561-1573, 2016 | 228 | 2016 |
Signalling properties of inorganic polyphosphate in the mammalian brain KM Holmström, N Marina, AY Baev, NW Wood, AV Gourine, AY Abramov Nature communications 4 (1), 1362, 2013 | 169 | 2013 |
Assessment of cardiac function in mice lacking the mitochondrial calcium uniporter KM Holmström, X Pan, JC Liu, S Menazza, J Liu, TT Nguyen, H Pan, ... Journal of molecular and cellular cardiology 85, 178-182, 2015 | 139 | 2015 |
Dopamine protects neurons against glutamate-induced excitotoxicity A Vaarmann, S Kovac, KM Holmström, S Gandhi, AY Abramov Cell death & disease 4 (1), e455-e455, 2013 | 129 | 2013 |
Unresolved questions from the analysis of mice lacking MCU expression E Murphy, X Pan, T Nguyen, J Liu, KM Holmström, T Finkel Biochemical and biophysical research communications 449 (4), 384-385, 2014 | 124 | 2014 |
Rare individual amyloid-β oligomers act on astrocytes to initiate neuronal damage P Narayan, KM Holmström, DH Kim, DJ Whitcomb, MR Wilson, ... Biochemistry 53 (15), 2442-2453, 2014 | 108 | 2014 |
The spatiotemporal regulation of the Keap1–Nrf2 pathway and its importance in cellular bioenergetics AT Dinkova-Kostova, L Baird, KM Holmström, CJ Meyer, AY Abramov Biochemical society transactions 43 (4), 602-610, 2015 | 85 | 2015 |
Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1 N Kieper, KM Holmström, D Ciceri, FC Fiesel, H Wolburg, E Ziviani, ... Experimental cell research 316 (7), 1213-1224, 2010 | 83 | 2010 |
Cyclophilin D-mediated regulation of the permeability transition pore is altered in mice lacking the mitochondrial calcium uniporter RJ Parks, S Menazza, KM Holmström, G Amanakis, M Fergusson, H Ma, ... Cardiovascular research 115 (2), 385-394, 2019 | 78 | 2019 |
Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology M Szibor, PK Dhandapani, E Dufour, KM Holmström, Y Zhuang, I Salwig, ... Disease models & mechanisms 10 (2), 163-171, 2017 | 75 | 2017 |