Partitioning and plasticity of repressive histone methylation states in mammalian chromatin AHFM Peters, S Kubicek, K Mechtler, RJ O'Sullivan, AAHA Derijck, ... Molecular cell 12 (6), 1577-1589, 2003 | 1366 | 2003 |
Telomeres: protecting chromosomes against genome instability RJ O'sullivan, J Karlseder Nature reviews Molecular cell biology 11 (3), 171-181, 2010 | 1164 | 2010 |
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase S Kubicek, RJ O'Sullivan, EM August, ER Hickey, Q Zhang, ML Teodoro, ... Molecular cell 25 (3), 473-481, 2007 | 955 | 2007 |
An epigenetic road map for histone lysine methylation M Lachner, RJ O'Sullivan, T Jenuwein Journal of cell science 116 (11), 2117-2124, 2003 | 869 | 2003 |
The profile of repeat‐associated histone lysine methylation states in the mouse epigenome JHA Martens, RJ O'Sullivan, U Braunschweig, S Opravil, M Radolf, ... The EMBO journal 24 (4), 800-812, 2005 | 787 | 2005 |
Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases M García-Cao, R O'Sullivan, AHFM Peters, T Jenuwein, MA Blasco Nature genetics 36 (1), 94-99, 2004 | 684 | 2004 |
Telomerase activation by genomic rearrangements in high-risk neuroblastoma M Peifer, F Hertwig, F Roels, D Dreidax, M Gartlgruber, R Menon, ... Nature 526 (7575), 700-704, 2015 | 640 | 2015 |
Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells BD Fodor, S Kubicek, M Yonezawa, RJ O’Sullivan, R Sengupta, ... Genes & development 20 (12), 1557-1562, 2006 | 458 | 2006 |
Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres RJ O'sullivan, S Kubicek, SL Schreiber, J Karlseder Nature structural & molecular biology 17 (10), 1218-1225, 2010 | 437 | 2010 |
TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA RL Flynn, RC Centore, RJ O’Sullivan, R Rai, A Tse, Z Songyang, S Chang, ... Nature 471 (7339), 532-536, 2011 | 417 | 2011 |
Suv39h-dependent H3K9me3 marks intact retrotransposons and silences LINE elements in mouse embryonic stem cells A Bulut-Karslioglu, A Inti, F Ramirez, M Barenboim, M Onishi-Seebacher, ... Molecular cell 55 (2), 277-290, 2014 | 344 | 2014 |
A mechanistic classification of clinical phenotypes in neuroblastoma S Ackermann, M Cartolano, B Hero, A Welte, Y Kahlert, A Roderwieser, ... Science 362 (6419), 1165-1170, 2018 | 319 | 2018 |
Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1 RJ O'sullivan, N Arnoult, DH Lackner, L Oganesian, C Haggblom, ... Nature structural & molecular biology 21 (2), 167-174, 2014 | 274 | 2014 |
Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis D Später, TP Hill, RJ O'sullivan, M Gruber, DA Conner, C Hartmann Oxford University Press for The Company of Biologists Limited 133 (15), 3039 …, 2006 | 254 | 2006 |
Alternative lengthening of telomeres and loss of DAXX/ATRX expression predicts metastatic disease and poor survival in patients with pancreatic neuroendocrine tumors AD Singhi, TC Liu, JL Roncaioli, D Cao, HJ Zeh, AH Zureikat, A Tsung, ... Clinical Cancer Research 23 (2), 600-609, 2017 | 226 | 2017 |
Asf1b, the necessary Asf1 isoform for proliferation, is predictive of outcome in breast cancer A Corpet, L De Koning, J Toedling, A Savignoni, F Berger, C Lemaître, ... The EMBO journal 30 (3), 480-493, 2011 | 181 | 2011 |
Proteomic profiling reveals a specific role for translesion DNA polymerase η in the alternative lengthening of telomeres L Garcia-Exposito, E Bournique, V Bergoglio, A Bose, J Barroso-Gonzalez, ... Cell reports 17 (7), 1858-1871, 2016 | 151 | 2016 |
The great unravelling: chromatin as a modulator of the aging process RJ O'Sullivan, J Karlseder Trends in biochemical sciences 37 (11), 466-476, 2012 | 119 | 2012 |
Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size WM Hackeng, LAA Brosens, JY Kim, R O'Sullivan, YN Sung, TC Liu, ... Gut 71 (5), 961-973, 2022 | 106 | 2022 |
Association analysis of the monoamine oxidase A and B genes with attention deficit hyperactivity disorder (ADHD) in an Irish sample: Preferential transmission of the MAO‐A 941G … K Domschke, K Sheehan, N Lowe, A Kirley, C Mullins, R O'sullivan, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 134 …, 2005 | 105 | 2005 |