Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene K Shimoda, J van Deursent, MY Sangster, SR Sarawar, RT Carson, ... Nature 380 (6575), 630-633, 1996 | 1660 | 1996 |
JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin BA Witthuhn, FW Quelle, O Silvennoinen, T Yi, B Tang, O Miura, JN Ihle Cell 74 (2), 227-236, 1993 | 1466 | 1993 |
Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 β receptor components N Stahl, TG Boulton, T Farruggella, NY Ip, S Davis, BA Witthuhn, ... Science 263 (5143), 92-95, 1994 | 1271 | 1994 |
Signaling by the cytokine receptor superfamily: JAKs and STATs JN Ihle, BA Witthuhn, FW Quelle, K Yamamoto, WE Thierfelder, B Kreider, ... Trends in biochemical sciences 19 (5), 222-227, 1994 | 871 | 1994 |
Signaling through the hematopoietic cytokine receptors. JN Ihle, BA Witthuhn, FW Quelle, K Yamamoto, O Silvennoinen Annual review of immunology 13, 369-398, 1995 | 829 | 1995 |
Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction. O Silvennoinen, BA Witthuhn, FW Quelle, JL Cleveland, T Yi, JN Ihle Proceedings of the National Academy of Sciences 90 (18), 8429-8433, 1993 | 635 | 1993 |
Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-& gamma; signal transduction pathway D Watling, D Guschin, M Müller, O Silvennoinen, BA Witthuhn, FW Quelle, ... Nature 366 (6451), 166-170, 1993 | 623 | 1993 |
JAK2 associates with the βc chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region FW Quelle, N Sato, BA Witthuhn, RC Inhorn, M Eder, A Miyajima, ... Molecular and cellular biology, 1994 | 594 | 1994 |
Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis FW Quelle, K Shimoda, W Thierfelder, C Fischer, A Kim, SM Ruben, ... Molecular and cellular biology, 1995 | 441 | 1995 |
Interleukin‐3 signals through multiple isoforms of Stat5. M Azam, H Erdjument‐Bromage, BL Kreider, M Xia, F Quelle, R Basu, ... The EMBO journal 14 (7), 1402-1411, 1995 | 417 | 1995 |
Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function C Korgaonkar, J Hagen, V Tompkins, AA Frazier, C Allamargot, ... Molecular and cellular biology 25 (4), 1258-1271, 2005 | 367 | 2005 |
Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response FW Quelle, D Wang, T Nosaka, WE Thierfelder, D Stravopodis, ... Molecular and cellular biology 16 (4), 1622-1631, 1996 | 315 | 1996 |
Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation K Yamamoto, FW Quelle, WE Thierfelder, BL Kreider, DJ Gilbert, ... Molecular and cellular biology 14 (7), 4342-4349, 1994 | 311 | 1994 |
Distribution of the mammalian Stat gene family in mouse chromosomes NG Copeland, DJ Gilbert, C Schindler, Z Zhong, Z Wen, JE Darnell Jr, ... Genomics 29 (1), 225-228, 1995 | 308 | 1995 |
Erythropoietin induces association of the JAK2 protein tyrosine kinase with the erythropoietin receptor in vivo O Miura, N Nakamura, FW Quelle, BA Witthuhn, JN Ihle, N Aoki Blood 84 (5), 1501-1507, 1994 | 210 | 1994 |
Phosphorylation and Activation of the DNA Binding Activity of Purified Stat1 by the Janus Protein-tyrosine Kinases and the Epidermal Growth Factor Receptor (∗) FW Quelle, W Thierfelder, BA Witthuhn, BO Tang, S Cohen, JN Ihle Journal of Biological Chemistry 270 (35), 20775-20780, 1995 | 193 | 1995 |
Jaks and Stats in cytokine signaling JN Ihle, T Nosaka, W Thierfelder, FW Quelle, K Shimoda Stem Cells 15 (S2), 105-112, 1997 | 165 | 1997 |
Induction of tyrosine phosphorylation of Vav and expression of Pim-1 correlates with Jak2-mediated growth signaling from the erythropoietin receptor O Miura, Y Miura, N Nakamura, FW Quelle, BA Witthuhn, JN Ihle, N Aoki | 161 | 1994 |
Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct Jak kinase signaling pathways FW Quelle, JL Wang, J Feng, D Wang, JL Cleveland, JN Ihle, GP Zambetti Genes & development 12 (8), 1099-1107, 1998 | 133 | 1998 |
Interleukin-9 Induces Tyrosine Phosphorylation of Insulin Receptor Substrate-1 via JAK Tyrosine Kinases (∗) T Yin, SR Keller, FW Quelle, BA Witthuhn, MLS Tsang, GE Lienhard, ... Journal of Biological Chemistry 270 (35), 20497-20502, 1995 | 132 | 1995 |