| Permanent inactivation of Huntington's disease mutation by personalized allele-specific CRISPR/Cas9 JW Shin, KH Kim, MJ Chao, RS Atwal, T Gillis, ME MacDonald, JF Gusella, ... Human molecular genetics 25 (20), 4566-4576, 2016 | 345 | 2016 |
| Nitric oxide induces expression of cyclooxygenase-2 in mouse skin through activation of NF-κB KS Chun, HH Cha, JW Shin, HK Na, KK Park, WY Chung, YJ Surh Carcinogenesis 25 (3), 445-454, 2004 | 157 | 2004 |
| Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification JW Shin, KS Chun, DH Kim, SJ Kim, SH Kim, NC Cho, HK Na, YJ Surh Biochemical Pharmacology 173, 113820, 2020 | 134 | 2020 |
| Antitumor promotional effects of a novel intestinal bacterial metabolite (IH-901) derived from the protopanaxadiol-type ginsenosides in mouse skin JY Lee, JW Shin, KS Chun, KK Park, WY Chung, YJ Bang, JH Sung, ... Carcinogenesis 26 (2), 359-367, 2005 | 132 | 2005 |
| Zerumbone induces heme oxygenase-1 expression in mouse skin and cultured murine epidermal cells through activation of Nrf2 JW Shin, K Ohnishi, A Murakami, JS Lee, JK Kundu, HK Na, H Ohigashi, ... Cancer prevention research 4 (6), 860-870, 2011 | 80 | 2011 |
| cis- 9, trans- 11-Conjugated linoleic acid down-regulates phorbol ester-induced NF-κB activation and subsequent COX-2 expression in … DM Hwang, JK Kundu, JW Shin, JC Lee, HJ Lee, YJ Surh Carcinogenesis 28 (2), 363-371, 2007 | 72 | 2007 |
| Docosahexaenoic acid inhibits UVB-induced activation of NF-κB and expression of COX-2 and NOX-4 in HR-1 hairless mouse skin by blocking MSK1 signaling MM Rahman, JK Kundu, JW Shin, HK Na, YJ Surh Plos one 6 (11), e28065, 2011 | 68 | 2011 |
| Genetic and functional analyses point to FAN1 as the source of multiple Huntington disease modifier effects KH Kim, EP Hong, JW Shin, MJ Chao, J Loupe, T Gillis, JS Mysore, ... The American Journal of Human Genetics 107 (1), 96-110, 2020 | 62 | 2020 |
| Thymoquinone inhibits phorbol ester-induced activation of NF-κB and expression of COX-2, and induces expression of cytoprotective enzymes in mouse skin in vivo JK Kundu, L Liu, JW Shin, YJ Surh Biochemical and biophysical research communications 438 (4), 721-727, 2013 | 61 | 2013 |
| Ultraviolet B radiation activates NF‐κB and induces iNOS expression in HR‐1 hairless mouse skin: role of IκB kinase‐β EJ Chang, JK Kundu, L Liu, JW Shin, YJ Surh Molecular Carcinogenesis 50 (4), 310-317, 2011 | 36 | 2011 |
| Population-specific genetic modification of Huntington's disease in Venezuela MJ Chao, KH Kim, JW Shin, D Lucente, VC Wheeler, H Li, JC Roach, ... PLoS genetics 14 (5), e1007274, 2018 | 34 | 2018 |
| Endogenous ω-3 Fatty Acid Production by fat-1 Transgene and Topically Applied Docosahexaenoic Acid Protect against UVB-induced Mouse Skin Carcinogenesis HW Yum, J Park, HJ Park, JW Shin, YY Cho, SJ Kim, JX Kang, YJ Surh Scientific Reports 7 (1), 11658, 2017 | 24 | 2017 |
| Phloretin inhibits phorbol ester–induced tumor promotion and expression of cyclooxygenase-2 in mouse skin: extracellular signal-regulated kinase and nuclear factor-κB as … JW Shin, JK Kundu, YJ Surh Journal of medicinal food 15 (3), 253-257, 2012 | 23 | 2012 |
| The prospects of CRISPR-based genome engineering in the treatment of neurodegenerative disorders JW Shin, JM Lee Therapeutic advances in neurological disorders 11, 1756285617741837, 2018 | 22 | 2018 |
| Allele-specific silencing of the gain-of-function mutation in Huntington’s disease using CRISPR/Cas9 JW Shin, EP Hong, SS Park, DE Choi, IS Seong, MN Whittaker, ... JCI insight 7 (19), e141042, 2022 | 20 | 2022 |
| Protein tyrosine phosphatases PTP-1B, SHP-2, and PTEN facilitate Rb/E2F-associated apoptotic signaling LD Morales, EA Casillas Pavón, JW Shin, A Garcia, M Capetillo, DJ Kim, ... PLoS One 9 (5), e97104, 2014 | 17 | 2014 |
| Novel allele-specific quantification methods reveal no effects of adult onset CAG repeats on HTT mRNA and protein levels A Shin, B Shin, JW Shin, KH Kim, RS Atwal, JM Hope, T Gillis, JD Leszyk, ... Human Molecular Genetics 26 (7), 1258-1267, 2017 | 15 | 2017 |
| PAM-altering SNP-based allele-specific CRISPR-Cas9 therapeutic strategies for Huntington’s disease JW Shin, EP Hong, SS Park, DE Choi, S Zeng, RZ Chen, JM Lee Molecular Therapy Methods & Clinical Development 26, 547-561, 2022 | 11 | 2022 |
| Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington’s disease DE Choi, JW Shin, S Zeng, EP Hong, JH Jang, JM Loupe, VC Wheeler, ... elife 12, RP89782, 2024 | 10 | 2024 |
| Genetic modifiers of somatic expansion and clinical phenotypes in Huntington’s disease reveal shared and tissue-specific effects Genetic Modifiers of Huntington’s Disease (GeM-HD) Consortium, JM Lee, ... bioRxiv, 2024.06. 10.597797, 2024 | 9 | 2024 |
