| Polymorphic toxin systems: comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics D Zhang, RF de Souza, V Anantharaman, LM Iyer, L Aravind Biology Direct 7 (1), 18, 2012 | 512 | 2012 |
| Discovery of novel DENN proteins: implications for the evolution of eukaryotic intracellular membrane structures and human disease D Zhang, LM Iyer, F He, L Aravind Frontiers in Genetics 3, 283, 2012 | 313 | 2012 |
| Comparative genomic analyses reveal a vast, novel network of nucleotide-centric systems in biological conflicts, immunity and signaling AM Burroughs, D Zhang, DE Schäffer, LM Iyer, L Aravind Nucleic acids research 43 (22), 10633-10654, 2015 | 240 | 2015 |
| A conserved NAD+ binding pocket that regulates protein-protein interactions during aging J Li, MS Bonkowski, S Moniot, D Zhang, BP Hubbard, AJY Ling, ... Science 355 (6331), 1312-1317, 2017 | 230 | 2017 |
| A novel immunity system for bacterial nucleic acid degrading toxins and its recruitment in various eukaryotic and DNA viral systems D Zhang, LM Iyer, L Aravind Nucleic acids research 39 (11), 4532-4552, 2011 | 202 | 2011 |
| Evolution of the deaminase fold and multiple origins of eukaryotic editing and mutagenic nucleic acid deaminases from bacterial toxin systems LM Iyer, D Zhang, IB Rogozin, L Aravind Nucleic acids research 39 (22), 9473-9497, 2011 | 197 | 2011 |
| The goldfish (Carassius auratus) as a model for neuroendocrine signaling JT Popesku, CJ Martyniuk, J Mennigen, H Xiong, D Zhang, X Xia, ... Molecular and cellular endocrinology 293 (1-2), 43-56, 2008 | 194 | 2008 |
| Adenine methylation in eukaryotes: Apprehending the complex evolutionary history and functional potential of an epigenetic modification LM Iyer, D Zhang, L Aravind Bioessays 38 (1), 27-40, 2016 | 183 | 2016 |
| O-GlcNAcylation destabilizes the active tetrameric PKM2 to promote the Warburg effect Y Wang, J Liu, X Jin, D Zhang, D Li, F Hao, Y Feng, S Gu, F Meng, M Tian, ... Proceedings of the National Academy of Sciences 114 (52), 13732-13737, 2017 | 151 | 2017 |
| Identification of novel families and classification of the C2 domain superfamily elucidate the origin and evolution of membrane targeting activities in eukaryotes D Zhang, L Aravind Gene 469 (1-2), 18-30, 2010 | 148 | 2010 |
| The natural history of ADP-ribosyltransferases and the ADP-ribosylation system L Aravind, D Zhang, RF de Souza, S Anand, LM Iyer Endogenous ADP-Ribosylation, 3-32, 2015 | 147 | 2015 |
| Integration of membrane and nuclear estrogen receptor signaling D Zhang, VL Trudeau Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2006 | 140 | 2006 |
| Auto-regulation of estrogen receptor subtypes and gene expression profiling of 17β-estradiol action in the neuroendocrine axis of male goldfish VL Marlatt, CJ Martyniuk, D Zhang, H Xiong, J Watt, X Xia, T Moon, ... Molecular and Cellular Endocrinology 283 (1-2), 38-48, 2008 | 135 | 2008 |
| Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA LM Iyer, D Zhang, A Maxwell Burroughs, L Aravind Nucleic acids research 41 (16), 7635-7655, 2013 | 131 | 2013 |
| Evolution of steroid-5α-reductases and comparison of their function with 5β-reductase VS Langlois, D Zhang, GM Cooke, VL Trudeau General and comparative endocrinology 166 (3), 489-497, 2010 | 106 | 2010 |
| Bacterial GRAS domain proteins throw new light on gibberellic acid response mechanisms D Zhang, LM Iyer, L Aravind Bioinformatics 28 (19), 2407-2411, 2012 | 104 | 2012 |
| EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia GV Pusapati, CE Hughes, KV Dorn, D Zhang, P Sugianto, L Aravind, ... Developmental cell 28 (5), 483-496, 2014 | 101 | 2014 |
| Novel immunoglobulin domain proteins provide insights into evolution and pathogenesis of SARS-CoV-2-related viruses Y Tan, T Schneider, M Leong, L Aravind, D Zhang MBio 11 (3), 10.1128/mbio. 00760-20, 2020 | 85* | 2020 |
| OST-HTH: a novel predicted RNA-binding domain V Anantharaman, D Zhang, L Aravind Biology direct 5, 1-8, 2010 | 79 | 2010 |
| Gene flow and biological conflict systems in the origin and evolution of eukaryotes L Aravind, V Anantharaman, D Zhang, R de Souza, LM Iyer Front. Cell. Inf. Microbio 2, 89, 2012 | 77 | 2012 |
Aravind LSenior Investigator, National Institutes of HealthEmail verificata su mail.nih.gov
