| Discodermolide, A Cytotoxic Marine Agent That Stabilizes Microtubules More Potently Than Taxol, E ter Haar, RJ Kowalski, E Hamel, CM Lin, RE Longley, SP Gunasekera, ... Biochemistry 35 (1), 243-250, 1996 | 607 | 1996 |
| Regulation of the autophagy protein LC3 by phosphorylation SJ Cherra III, SM Kulich, G Uechi, M Balasubramani, J Mountzouris, ... Journal of Cell Biology 190 (4), 533-539, 2010 | 386 | 2010 |
| A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach TL Nguyen, C McGrath, AR Hermone, JC Burnett, DW Zaharevitz, BW Day, ... Journal of medicinal chemistry 48 (19), 6107-6116, 2005 | 366 | 2005 |
| Structure-activity analysis of the interaction of curacin A, the potent colchicine site antimitotic agent, with tubulin and effects of analogs on the growth of MCF-7 breast … P Verdier-Pinard, JY Lai, HD Yoo, J Yu, B Marquez, DG Nagle, M Nambu, ... Molecular pharmacology 53 (1), 62-76, 1998 | 355 | 1998 |
| The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more … RJ Kowalski, P Giannakakou, SP Gunasekera, RE Longley, BW Day, ... Molecular pharmacology 52 (4), 613-622, 1997 | 342 | 1997 |
| Theory and applications of surface plasmon resonance, resonant mirror, resonant waveguide grating, and dual polarization interferometry biosensors HN Daghestani, BW Day Sensors 10 (11), 9630-9646, 2010 | 326 | 2010 |
| Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages G Molina, A Vogt, A Bakan, W Dai, PQ De Oliveira, W Znosko, ... Nature chemical biology 5 (9), 680-687, 2009 | 293 | 2009 |
| Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity SW Fewell, CM Smith, MA Lyon, TP Dumitrescu, P Wipf, BW Day, ... Journal of Biological Chemistry 279 (49), 51131-51140, 2004 | 256 | 2004 |
| APC is essential for targeting phosphorylated β-catenin to the SCFβ-TrCP ubiquitin ligase YY Su, C Fu, S Ishikawa, A Stella, M Kojima, K Shitoh, EM Schreiber, ... Molecular cell 32 (5), 652-661, 2008 | 254 | 2008 |
| Histone deacetylase inhibitor enhances recovery after AKI CC Cosentino, NI Skrypnyk, LL Brilli, T Chiba, T Novitskaya, C Woods, ... Journal of the American Society of Nephrology 24 (6), 943-953, 2013 | 199 | 2013 |
| Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites RM Buey, E Calvo, I Barasoain, O Pineda, MC Edler, R Matesanz, ... Nature chemical biology 3 (2), 117-125, 2007 | 180 | 2007 |
| Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum AN Chiang, JC Valderramos, R Balachandran, RJ Chovatiya, BP Mead, ... Bioorganic & medicinal chemistry 17 (4), 1527-1533, 2009 | 173 | 2009 |
| Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly E Hamel, BW Day, JH Miller, MK Jung, PT Northcote, AK Ghosh, ... Molecular pharmacology 70 (5), 1555-1564, 2006 | 165 | 2006 |
| A functionalizable polyester with free hydroxyl groups and tunable physiochemical and biological properties Z You, H Cao, J Gao, PH Shin, BW Day, Y Wang Biomaterials 31 (12), 3129-3138, 2010 | 164 | 2010 |
| Reduction of ferrylmyoglobin and ferrylhemoglobin by nitric oxide: a protective mechanism against ferryl hemoprotein-induced oxidations NV Gorbunov, AN Osipov, BW Day, B Zayas-Rivera, VE Kagan, ... Biochemistry 34 (20), 6689-6699, 1995 | 162 | 1995 |
| Mild, Efficient Friedel−Crafts Acylations from Carboxylic Acids Using Cyanuric Chloride and AlCl3 CO Kangani, BW Day Organic letters 10 (13), 2645-2648, 2008 | 145 | 2008 |
| Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas ME Beckner, W Fellows‐Mayle, Z Zhang, NR Agostino, JA Kant, BW Day, ... International Journal of Cancer 126 (10), 2282-2295, 2010 | 138 | 2010 |
| Inhibition of histone deacetylase expands the renal progenitor cell population ED de Groh, LM Swanhart, CC Cosentino, RL Jackson, W Dai, ... Journal of the American Society of Nephrology 21 (5), 794-802, 2010 | 131 | 2010 |
| Meayamycin inhibits pre–messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells BJ Albert, PA McPherson, K O'Brien, NL Czaicki, V DeStefino, S Osman, ... Molecular cancer therapeutics 8 (8), 2308-2318, 2009 | 129 | 2009 |
| Orphan nuclear receptor pregnane X receptor sensitizes oxidative stress responses in transgenic mice and cancerous cells H Gong, SV Singh, SP Singh, Y Mu, JH Lee, SPS Saini, D Toma, S Ren, ... Molecular endocrinology 20 (2), 279-290, 2006 | 129 | 2006 |
Peter WipfProfessor of Chemistry, University of PittsburghEmail verificata su pitt.edu