Adenylyl cyclase amino acid sequence: possible channel-or transporter-like structure J Krupinski, F Coussen, HA Bakalyar, WJ Tang, PG Feinstein, K Orth, ... Science 244 (4912), 1558-1564, 1989 | 904 | 1989 |
Molecular Ordering of the Cell Death Pathway: Bcl-2 AND Bcl-xL Function upstream of the CED-3-like apoptotic proteases (∗) AM Chinnaiyan, K Orth, K O'Rourke, H Duan, GG Poirier, VM Dixit Journal of Biological Chemistry 271 (9), 4573-4576, 1996 | 768 | 1996 |
Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation S Mukherjee, G Keitany, Y Li, Y Wang, HL Ball, EJ Goldsmith, K Orth Science 312 (5777), 1211-1214, 2006 | 742 | 2006 |
Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease K Orth, Z Xu, MB Mudgett, ZQ Bao, LE Palmer, JB Bliska, WF Mangel, ... Science 290 (5496), 1594-1597, 2000 | 691 | 2000 |
Target protease specificity of the viral serpin CrmA: analysis of five caspases Q Zhou, S Snipas, K Orth, M Muzio, VM Dixit, GS Salvesen Journal of Biological Chemistry 272 (12), 7797-7800, 1997 | 689 | 1997 |
The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A K Orth, AM Chinnaiyan, M Garg, CJ Froelich, VM Dixit Journal of Biological Chemistry 271 (28), 16443-16446, 1996 | 611 | 1996 |
Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade B Levkau, H Koyama, EW Raines, BE Clurman, B Herren, K Orth, ... Molecular cell 1 (4), 553-563, 1998 | 594 | 1998 |
Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of … TE Willnow, JL Goldstein, K Orth, MS Brown, J Herz Journal of Biological Chemistry 267 (36), 26172-26180, 1992 | 560 | 1992 |
Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector K Orth, LE Palmer, ZQ Bao, S Stewart, AE Rudolph, JB Bliska, JE Dixon Science 285 (5435), 1920-1923, 1999 | 528 | 1999 |
AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling ML Yarbrough, Y Li, LN Kinch, NV Grishin, HL Ball, K Orth science 323 (5911), 269-272, 2009 | 488 | 2009 |
New paradigm for lymphocyte granule-mediated cytotoxicity: target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and … CJ Froelich, K Orth, J Turbov, P Seth, R Gottlieb, B Babior, GM Shah, ... Journal of Biological Chemistry 271 (46), 29073-29079, 1996 | 486 | 1996 |
Vibrio parahaemolyticus cell biology and pathogenicity determinants CA Broberg, TJ Calder, K Orth Microbes and infection 13 (12-13), 992-1001, 2011 | 485 | 2011 |
Cleavage of focal adhesion kinase by caspases during apoptosis LP Wen, JA Fahrni, S Troie, JL Guan, K Orth, GD Rosen Journal of Biological Chemistry 272 (41), 26056-26061, 1997 | 471 | 1997 |
ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B H Duan, K Orth, AM Chinnaiyan, GG Poirier, CJ Froelich, WW He, ... Journal of Biological Chemistry 271 (28), 16720-16724, 1996 | 417 | 1996 |
Cutting edge: Salmonella AvrA effector inhibits the key proinflammatory, anti-apoptotic NF-κB pathway LS Collier-Hyams, H Zeng, J Sun, AD Tomlinson, ZQ Bao, H Chen, ... The Journal of Immunology 169 (6), 2846-2850, 2002 | 361 | 2002 |
Xanthomonas type III effector XopD targets SUMO‐conjugated proteins in planta A Hotson, R Chosed, H Shu, K Orth, MB Mudgett Molecular microbiology 50 (2), 377-389, 2003 | 321 | 2003 |
Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor … K Orth, EL Madison, MJ Gething, JF Sambrook, J Herz Proceedings of the National Academy of Sciences 89 (16), 7422-7426, 1992 | 316 | 1992 |
Targeting the bacteria–host interface: strategies in anti-adhesion therapy AM Krachler, K Orth Virulence 4 (4), 284-294, 2013 | 284 | 2013 |
Virulence determinants for Vibrio parahaemolyticus infection L Zhang, K Orth Current opinion in microbiology 16 (1), 70-77, 2013 | 278 | 2013 |
A distinctive role for the Yersinia protein kinase: Actin binding, kinase activation, and cytoskeleton disruption SJ Juris, AE Rudolph, D Huddler, K Orth, JE Dixon Proceedings of the National Academy of Sciences 97 (17), 9431-9436, 2000 | 264 | 2000 |