GREAT improves functional interpretation of cis-regulatory regions CY McLean, D Bristor, M Hiller, SL Clarke, BT Schaar, CB Lowe, ... Nature biotechnology 28 (5), 495-501, 2010 | 4461 | 2010 |
The power of genetic diversity in genome-wide association studies of lipids SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ... Nature 600 (7890), 675-679, 2021 | 573 | 2021 |
Coding exons function as tissue-specific enhancers of nearby genes RY Birnbaum, EJ Clowney, O Agamy, MJ Kim, J Zhao, T Yamanaka, ... Genome research 22 (6), 1059-1068, 2012 | 265 | 2012 |
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations C Tcheandjieu, X Zhu, AT Hilliard, SL Clarke, V Napolioni, S Ma, KM Lee, ... Nature medicine 28 (8), 1679-1692, 2022 | 198 | 2022 |
A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease AP Patel, M Wang, Y Ruan, S Koyama, SL Clarke, X Yang, C Tcheandjieu, ... Nature Medicine 29 (7), 1793-1803, 2023 | 104 | 2023 |
Human developmental enhancers conserved between deuterostomes and protostomes SL Clarke, JE VanderMeer, AM Wenger, BT Schaar, N Ahituv, G Bejerano PLoS genetics 8 (8), e1002852, 2012 | 81 | 2012 |
Validation of an integrated risk tool, including polygenic risk score, for atherosclerotic cardiovascular disease in multiple ethnicities and ancestries ME Weale, F Riveros-Mckay, S Selzam, P Seth, R Moore, WA Tarran, ... The American journal of cardiology 148, 157-164, 2021 | 65 | 2021 |
Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits RA Patel, SA Musharoff, JP Spence, H Pimentel, C Tcheandjieu, ... The American Journal of Human Genetics 109 (7), 1286-1297, 2022 | 60* | 2022 |
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential T Nakao, AG Bick, MA Taub, SM Zekavat, MM Uddin, A Niroula, CL Carty, ... Science advances 8 (14), eabl6579, 2022 | 55* | 2022 |
Familial hypercholesterolemia HE Ison, SL Clarke, JW Knowles | 40 | 2022 |
Combining Clinical and Polygenic Risk Improves Stroke Prediction Among Individuals With Atrial Fibrillation JW O'Sullivan, A Shcherbina, JM Justesen, M Turakhia, M Perez, H Wand, ... Circulation: Genomic and Precision Medicine 14 (e003168), 2021 | 40 | 2021 |
Genome-wide association studies of coronary artery disease: recent progress and challenges ahead SL Clarke, TL Assimes Current atherosclerosis reports 20, 1-11, 2018 | 39 | 2018 |
ZEB2 Shapes the Epigenetic Landscape of Atherosclerosis P Cheng, RC Wirka, L Shoa Clarke, Q Zhao, R Kundu, T Nguyen, S Nair, ... Circulation 145 (6), 469-485, 2022 | 38 | 2022 |
PRISM offers a comprehensive genomic approach to transcription factor function prediction AM Wenger, SL Clarke, H Guturu, J Chen, BT Schaar, CY McLean, ... Genome research 23 (5), 889-904, 2013 | 38 | 2013 |
The enhancer landscape during early neocortical development reveals patterns of dense regulation and co-option AM Wenger, SL Clarke, JH Notwell, T Chung, G Tuteja, H Guturu, ... PLoS genetics 9 (8), e1003728, 2013 | 35 | 2013 |
Control of pelvic girdle development by genes of the Pbx family and Emx2 TD Capellini, K Handschuh, L Quintana, E Ferretti, G Di Giacomo, ... Developmental Dynamics 240 (5), 1173-1189, 2011 | 35 | 2011 |
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis S Kanoni, SE Graham, Y Wang, I Surakka, S Ramdas, X Zhu, SL Clarke, ... Genome biology 23 (1), 268, 2022 | 34 | 2022 |
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids S Ramdas, J Judd, SE Graham, S Kanoni, Y Wang, I Surakka, B Wenz, ... The American Journal of Human Genetics 109 (8), 1366-1387, 2022 | 29 | 2022 |
Cardiorespiratory fitness, body mass index, and markers of insulin resistance in apparently healthy women and men SL Clarke, GM Reaven, D Leonard, CE Barlow, WL Haskell, BL Willis, ... The American journal of medicine 133 (7), 825-830. e2, 2020 | 27 | 2020 |
Confounders mediate AI prediction of demographics in medical imaging G Duffy, SL Clarke, M Christensen, B He, N Yuan, S Cheng, D Ouyang NPJ digital medicine 5 (1), 188, 2022 | 24 | 2022 |