Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control B Zhao, X Wei, W Li, RS Udan, Q Yang, J Kim, J Xie, T Ikenoue, J Yu, L Li, ... Genes & development 21 (21), 2747-2761, 2007 | 3247 | 2007 |
A selective TrkB agonist with potent neurotrophic activities by 7, 8-dihydroxyflavone SW Jang, X Liu, M Yepes, KR Shepherd, GW Miller, Y Liu, WD Wilson, ... Proceedings of the National Academy of Sciences 107 (6), 2687-2692, 2010 | 733 | 2010 |
Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo X Bai, F Cerimele, M Ushio-Fukai, M Waqas, PM Campbell, ... Journal of biological chemistry 278 (37), 35501-35507, 2003 | 451 | 2003 |
Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth T Hitosugi, L Zhou, S Elf, J Fan, HB Kang, JH Seo, C Shan, Q Dai, ... Cancer cell 22 (5), 585-600, 2012 | 445 | 2012 |
Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells K Ye, Y Ke, N Keshava, J Shanks, JA Kapp, RR Tekmal, J Petros, ... Proceedings of the National Academy of Sciences 95 (4), 1601-1606, 1998 | 440 | 1998 |
Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease Z Zhang, M Song, X Liu, SS Kang, IS Kwon, DM Duong, NT Seyfried, ... Nature medicine 20 (11), 1254-1262, 2014 | 437 | 2014 |
Dexras1: AG protein specifically coupled to neuronal nitric oxide synthase via CAPON M Fang, SR Jaffrey, A Sawa, K Ye, X Luo, SH Snyder Neuron 28 (1), 183-193, 2000 | 385 | 2000 |
PI3 kinase enhancer–Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis R Rong, JY Ahn, H Huang, E Nagata, D Kalman, JA Kapp, J Tu, ... Nature neuroscience 6 (11), 1153-1161, 2003 | 337 | 2003 |
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling R Lin, S Elf, C Shan, HB Kang, Q Ji, L Zhou, T Hitosugi, L Zhang, S Zhang, ... Nature cell biology 17 (11), 1484-1496, 2015 | 282 | 2015 |
Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome C Gross, M Nakamoto, X Yao, CB Chan, SY Yim, K Ye, ST Warren, ... Journal of Neuroscience 30 (32), 10624-10638, 2010 | 279 | 2010 |
Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer’s disease Z Zhang, M Song, X Liu, S Su Kang, DM Duong, NT Seyfried, X Cao, ... Nature communications 6 (1), 8762, 2015 | 274 | 2015 |
Effect of 7, 8-dihydroxyflavone, a small-molecule TrkB agonist, on emotional learning R Andero, SA Heldt, K Ye, X Liu, A Armario, KJ Ressler American Journal of Psychiatry 168 (2), 163-172, 2011 | 249 | 2011 |
7, 8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer’s disease Z Zhang, X Liu, JP Schroeder, CB Chan, M Song, SP Yu, D Weinshenker, ... Neuropsychopharmacology 39 (3), 638-650, 2014 | 248 | 2014 |
Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns (3, 4, 5) P3 interactions HR Luo, YE Huang, JC Chen, A Saiardi, M Iijima, K Ye, Y Huang, ... Cell 114 (5), 559-572, 2003 | 235 | 2003 |
A synthetic 7, 8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect X Liu, CB Chan, SW Jang, S Pradoldej, J Huang, K He, LH Phun, ... Journal of medicinal chemistry 53 (23), 8274-8286, 2010 | 232 | 2010 |
Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear DC Choi, KA Maguschak, K Ye, SW Jang, KM Myers, KJ Ressler Proceedings of the National Academy of Sciences 107 (6), 2675-2680, 2010 | 232 | 2010 |
Gut microbiota regulate Alzheimer’s disease pathologies and cognitive disorders via PUFA-associated neuroinflammation C Chen, J Liao, Y Xia, X Liu, R Jones, J Haran, B McCormick, ... Gut 71 (11), 2233-2252, 2022 | 228 | 2022 |
SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination HB Luo, YY Xia, XJ Shu, ZC Liu, Y Feng, XH Liu, G Yu, G Yin, YS Xiong, ... Proceedings of the National Academy of Sciences 111 (46), 16586-16591, 2014 | 225 | 2014 |
Reactive oxygen species-induced actin glutathionylation controls actin dynamics in neutrophils J Sakai, J Li, KK Subramanian, S Mondal, B Bajrami, H Hattori, Y Jia, ... Immunity 37 (6), 1037-1049, 2012 | 215 | 2012 |
N-acetylserotonin activates TrkB receptor in a circadian rhythm SW Jang, X Liu, S Pradoldej, G Tosini, Q Chang, PM Iuvone, K Ye Proceedings of the National Academy of Sciences 107 (8), 3876-3881, 2010 | 210 | 2010 |