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Benoit de Crombrugghe
Benoit de Crombrugghe
UTMDAnderson Cancer Cente
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Anno
The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
K Nakashima, X Zhou, G Kunkel, Z Zhang, JM Deng, RR Behringer, ...
Cell 108 (1), 17-29, 2002
45792002
Sox9 is required for cartilage formation
W Bi, JM Deng, Z Zhang, RR Behringer, B De Crombrugghe
Nature genetics 22 (1), 85-89, 1999
22141999
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
H Akiyama, MC Chaboissier, JF Martin, A Schedl, B De Crombrugghe
Genes & development 16 (21), 2813-2828, 2002
22132002
Some recent advances in the chemistry and biology of transforming growth factor-beta.
MB Sporn, AB Roberts, LM Wakefield, B de Crombrugghe
The Journal of cell biology 105 (3), 1039-1045, 1987
16701987
SOX9 is a potent activator of the chondrocyte-specific enhancer of the proα1 (II) collagen gene
V Lefebvre, W Huang, VR Harley, PN Goodfellow, B De Crombrugghe
Molecular and cellular biology, 1997
13231997
Evidence for two functional gal promoters in intact Escherichia coli cells.
H Aiba, S Adhya, B de Crombrugghe
Journal of Biological Chemistry 256 (22), 11905-11910, 1981
11601981
A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene
V Lefebvre, P Li, B De Crombrugghe
The EMBO journal 17 (19), 5718-5733, 1998
10081998
Interactions between Sox9 and β-catenin control chondrocyte differentiation
H Akiyama, JP Lyons, Y Mori-Akiyama, X Yang, R Zhang, Z Zhang, ...
Genes & development 18 (9), 1072-1087, 2004
9562004
Cyclic AMP receptor protein: role in transcription activation
B De Crombrugghe, S Busby, H Buc
Science 224 (4651), 831-838, 1984
7651984
A nuclear factor 1 binding site mediates the transcriptional activation of a type I collagen promoter by transforming growth factor-β
P Rossi, G Karsenty, AB Roberts, NS Roche, MB Sporn, ...
Cell 52 (3), 405-414, 1988
7431988
The transcription factors L-Sox5 and Sox6 are essential for cartilage formation
P Smits, P Li, J Mandel, Z Zhang, JM Deng, RR Behringer, ...
Developmental cell 1 (2), 277-290, 2001
7372001
The family of collagen genes
E Vuorio, B De Crombrugghe
Annual review of biochemistry 59 (1), 837-872, 1990
7271990
Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization
W Bi, W Huang, DJ Whitworth, JM Deng, Z Zhang, RR Behringer, ...
Proceedings of the National Academy of Sciences 98 (12), 6698-6703, 2001
6952001
Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis
Q Zhao, H Eberspaecher, V Lefebvre, B de Crombrugghe
Developmental dynamics: an official publication of the American Association …, 1997
6911997
Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors
H Akiyama, JE Kim, K Nakashima, G Balmes, N Iwai, JM Deng, Z Zhang, ...
Proceedings of the National Academy of Sciences 102 (41), 14665-14670, 2005
6792005
Chondrocytes transdifferentiate into osteoblasts in endochondral bone during development, postnatal growth and fracture healing in mice
X Zhou, K Von Der Mark, S Henry, W Norton, H Adams, ...
PLoS genetics 10 (12), e1004820, 2014
6192014
Regulatory mechanisms in the pathways of cartilage and bone formation
B de Crombrugghe, V Lefebvre, K Nakashima
Current opinion in cell biology 13 (6), 721-728, 2001
6142001
Transcriptional mechanisms in osteoblast differentiation and bone formation
K Nakashima, B de Crombrugghe
TRENDS in Genetics 19 (8), 458-466, 2003
6072003
Transcriptional mechanisms of chondrocyte differentiation
B De Crombrugghe, V Lefebvre, RR Behringer, W Bi, S Murakami, ...
Matrix Biology 19 (5), 389-394, 2000
5952000
NFAT and Osterix cooperatively regulate bone formation
T Koga, Y Matsui, M Asagiri, T Kodama, B de Crombrugghe, K Nakashima, ...
Nature medicine 11 (8), 880-885, 2005
5762005
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