| Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance TR Koves, JR Ussher, RC Noland, D Slentz, M Mosedale, O Ilkayeva, ... Cell metabolism 7 (1), 45-56, 2008 | 2190 | 2008 |
| Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes DM Muoio, CB Newgard Nature reviews Molecular cell biology 9 (3), 193-205, 2008 | 1641 | 2008 |
| Energy metabolism in uncoupling protein 3 gene knockout mice AJ Vidal-Puig, D Grujic, CY Zhang, T Hagen, O Boss, Y Ido, A Szczepanik, ... Journal of Biological Chemistry 275 (21), 16258-16266, 2000 | 825 | 2000 |
| The failing heart relies on ketone bodies as a fuel G Aubert, OJ Martin, JL Horton, L Lai, RB Vega, TC Leone, T Koves, ... Circulation 133 (8), 698-705, 2016 | 671 | 2016 |
| Leptin directly alters lipid partitioning in skeletal muscle DM Muoio, GL Dohn, FT Fiedorek Jr, EB Tapscott, RA Coleman Diabetes 46 (8), 1360-1363, 1997 | 636 | 1997 |
| Genome-wide chromatin state transitions associated with developmental and environmental cues J Zhu, M Adli, JY Zou, G Verstappen, M Coyne, X Zhang, T Durham, ... Cell 152 (3), 642-654, 2013 | 626 | 2013 |
| Peroxisome proliferator-activated receptor-γ co-activator 1α-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced … TR Koves, P Li, J An, T Akimoto, D Slentz, O Ilkayeva, GL Dohm, Z Yan, ... Journal of Biological Chemistry 280 (39), 33588-33598, 2005 | 575 | 2005 |
| Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance J An, DM Muoio, M Shiota, Y Fujimoto, GW Cline, GI Shulman, TR Koves, ... Nature medicine 10 (3), 268-274, 2004 | 543 | 2004 |
| AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a … DM Muoio, K Seefeld, LA Witters, RA Coleman Biochemical Journal 338 (3), 783-791, 1999 | 540 | 1999 |
| Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) α knock-out mice: evidence for … DM Muoio, PS MacLean, DB Lang, S Li, JA Houmard, JM Way, ... Journal of Biological Chemistry 277 (29), 26089-26097, 2002 | 532 | 2002 |
| Understanding the cellular and molecular mechanisms of physical activity-induced health benefits PD Neufer, MM Bamman, DM Muoio, C Bouchard, DM Cooper, ... Cell metabolism 22 (1), 4-11, 2015 | 524 | 2015 |
| Obesity-related derangements in metabolic regulation DM Muoio, CB Newgard Annu. Rev. Biochem. 75 (1), 367-401, 2006 | 470 | 2006 |
| Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans MW Hulver, JR Berggren, MJ Carper, M Miyazaki, JM Ntambi, EP Hoffman, ... Cell metabolism 2 (4), 251-261, 2005 | 457 | 2005 |
| Physiological and nutritional regulation of enzymes of triacylglycerol synthesis RA Coleman, TM Lewin, DM Muoio Annual review of nutrition 20 (1), 77-103, 2000 | 427 | 2000 |
| Metabolic inflexibility: when mitochondrial indecision leads to metabolic gridlock DM Muoio Cell 159 (6), 1253-1262, 2014 | 423 | 2014 |
| Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption JR Ussher, TR Koves, VJJ Cadete, L Zhang, JS Jaswal, SJ Swyrd, ... Diabetes 59 (10), 2453-2464, 2010 | 416 | 2010 |
| Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control RC Noland, TR Koves, SE Seiler, H Lum, RM Lust, O Ilkayeva, ... Journal of biological chemistry 284 (34), 22840-22852, 2009 | 414 | 2009 |
| Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility DM Muoio, RC Noland, JP Kovalik, SE Seiler, MN Davies, KL DeBalsi, ... Cell metabolism 15 (5), 764-777, 2012 | 408 | 2012 |
| SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase G Laurent, NJ German, AK Saha, VCJ de Boer, M Davies, TR Koves, ... Molecular cell 50 (5), 686-698, 2013 | 404 | 2013 |
| Metabolomics applied to diabetes research: moving from information to knowledge JR Bain, RD Stevens, BR Wenner, O Ilkayeva, DM Muoio, CB Newgard Diabetes 58 (11), 2429-2443, 2009 | 393 | 2009 |