| A Partially Folded Structure of Amyloid-Beta (1-40) in an Aqueous Environment S Vivekanandan, JR Brender, SY Lee, A Ramamoorthy Biochemical and Biophysical Research Communications, 2011 | 489 | 2011 |
| Differences between amyloid-β aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease SA Kotler, P Walsh, JR Brender, A Ramamoorthy Chemical Society reviews 43, 6692-6700, 2014 | 419 | 2014 |
| Two-Step Mechanism of Membrane Disruption by A< i> β</i> through Membrane Fragmentation and Pore Formation MFM Sciacca, SA Kotler, JR Brender, J Chen, D Lee, A Ramamoorthy Biophysical Journal 103 (4), 702-710, 2012 | 407 | 2012 |
| Membrane Disruption and Early Events in the Aggregation of the Diabetes Related Peptide IAPP from a Molecular Perspective JR Brender, S Salamekh, A Ramamoorthy Accounts of Chemical Research, 2011 | 402 | 2011 |
| Determining the effects of lipophilic drugs on membrane structure by solid-state NMR spectroscopy: the case of the antioxidant curcumin J Barry, M Fritz, JR Brender, PES Smith, DK Lee, A Ramamoorthy Journal of the American Chemical Society 131 (12), 4490-4498, 2009 | 346 | 2009 |
| Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment RPR Nanga, JR Brender, S Vivekanandan, A Ramamoorthy Biochimica et Biophysica Acta (BBA)-Biomembranes, 2011 | 314 | 2011 |
| Inhibition of Amyloid Peptide Fibrillation by Inorganic Nanoparticles: Functional Similarities with Proteins SI Yoo, M Yang, JR Brender, V Subramanian, K Sun, NE Joo, SH Jeong, ... Angewandte Chemie International Edition 50 (22), 5110-5115, 2011 | 303 | 2011 |
| Role of zinc in human islet amyloid polypeptide aggregation JR Brender, K Hartman, RPR Nanga, N Popovych, R de la Salud Bea, ... Journal of the American Chemical Society 132 (26), 8973-8983, 2010 | 270 | 2010 |
| Insights into antiamyloidogenic properties of the green tea extract (−)-epigallocatechin-3-gallate toward metal-associated amyloid-β species SJ Hyung, AS DeToma, JR Brender, S Lee, S Vivekanandan, A Kochi, ... Proceedings of the National Academy of Sciences 110 (10), 3743-3748, 2013 | 262 | 2013 |
| Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide JR Brender, EL Lee, MA Cavitt, A Gafni, DG Steel, A Ramamoorthy Journal of the American Chemical Society 130 (20), 6424-6429, 2008 | 262 | 2008 |
| Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer’s disease S Lee, X Zheng, J Krishnamoorthy, MG Savelieff, HM Park, JR Brender, ... Journal of the American Chemical Society 136 (1), 299-310, 2014 | 209 | 2014 |
| Structures of Rat and Human Islet Amyloid Polypeptide IAPP1− 19 in Micelles by NMR Spectroscopy† RPR Nanga, JR Brender, J Xu, G Veglia, A Ramamoorthy Biochemistry 47 (48), 12689-12697, 2008 | 208 | 2008 |
| Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide PES Smith, JR Brender, A Ramamoorthy Journal of the American Chemical Society 131 (12), 4470-4478, 2009 | 179 | 2009 |
| Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy RPR Nanga, JR Brender, J Xu, K Hartman, V Subramanian, ... Journal of the American Chemical Society 131 (23), 8252-8261, 2009 | 173 | 2009 |
| A Single Mutation in the Nonamyloidogenic Region of Islet Amyloid Polypeptide Greatly Reduces Toxicity† JR Brender, K Hartman, KR Reid, RT Kennedy, A Ramamoorthy Biochemistry 47 (48), 12680-12688, 2008 | 172 | 2008 |
| Association of highly compact type II diabetes related islet amyloid polypeptide intermediate species at physiological temperature revealed by diffusion NMR spectroscopy R Soong, JR Brender, PM Macdonald, A Ramamoorthy Journal of the American Chemical Society 131 (20), 7079-7085, 2009 | 162 | 2009 |
| Membrane fragmentation by an amyloidogenic fragment of human islet amyloid polypeptide detected by solid-state NMR spectroscopy of membrane nanotubes JR Brender, UHN Dürr, D Heyl, MB Budarapu, A Ramamoorthy Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (9), 2026-2029, 2007 | 155 | 2007 |
| Predicting the effect of mutations on protein-protein binding interactions through structure-based interface profiles JR Brender, Y Zhang PLoS computational biology 11 (10), e1004494, 2015 | 154 | 2015 |
| Alternative Pathways of Human Islet Amyloid Polypeptide Aggregation Distinguished by 19F Nuclear Magnetic Resonance-Detected Kinetics of Monomer … Y Suzuki, JR Brender, K Hartman, A Ramamoorthy, ENG Marsh Biochemistry 51 (41), 8154-8162, 2012 | 142 | 2012 |
| Frontiers: Does Cholesterol Play a Role in the Bacterial Selectivity of Antimicrobial Peptides? JR Brender, AJ McHenry, A Ramamoorthy Frontiers in Molecular Innate Immunity 3, 2012 | 142* | 2012 |
Ayyalusamy RamamoorthyProfessor of Chemical and Biomedical Engineering, National High Magnetic Field LaboratoryEmail verificata su fsu.edu