Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery SR Datta, H Dudek, X Tao, S Masters, H Fu, Y Gotoh, ME Greenberg Cell 91 (2), 231-241, 1997 | 7509 | 1997 |
14-3-3 proteins: structure, function, and regulation H Fu, RR Subramanian, SC Masters Annual review of pharmacology and toxicology 40 (1), 617-647, 2000 | 2001 | 2000 |
Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition SY Sun, LM Rosenberg, X Wang, Z Zhou, P Yue, H Fu, FR Khuri Cancer research 65 (16), 7052-7058, 2005 | 957 | 2005 |
Crystal structure of the zeta isoform of the 14-3-3 protein D Liu, J Bienkowska, C Petosa, RJ Collier, H Fu, R Liddington Nature 376 (6536), 191-194, 1995 | 673 | 1995 |
Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins L Zhang, J Chen, H Fu Proceedings of the National Academy of Sciences 96 (15), 8511-8515, 1999 | 474 | 1999 |
Targeting protein–protein interactions as an anticancer strategy AA Ivanov, FR Khuri, H Fu Trends in pharmacological sciences 34 (7), 393-400, 2013 | 444 | 2013 |
14-3-3ζ binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove C Petosa, SC Masters, LA Bankston, J Pohl, B Wang, H Fu, RC Liddington Journal of Biological Chemistry 273 (26), 16305-16310, 1998 | 425 | 1998 |
Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK–ERK independent mechanism J Chen, K Fujii, L Zhang, T Roberts, H Fu Proceedings of the National Academy of Sciences 98 (14), 7783-7788, 2001 | 404 | 2001 |
14-3-3 proteins mediate an essential anti-apoptotic signal SC Masters, H Fu Journal of Biological Chemistry 276 (48), 45193-45200, 2001 | 390 | 2001 |
An improved Tn7-based system for the single-copy insertion of cloned genes into chromosomes of gram-negative bacteria Y Bao, DP Lies, H Fu, GP Roberts Gene 109 (1), 167-168, 1991 | 384 | 1991 |
Isolation of high-affinity peptide antagonists of 14-3-3 proteins by phage display B Wang, H Yang, YC Liu, T Jelinek, L Zhang, E Ruoslahti, H Fu Biochemistry 38 (38), 12499-12504, 1999 | 374 | 1999 |
The eukaryotic host factor that activates exoenzyme S of Pseudomonas aeruginosa is a member of the 14-3-3 protein family. H Fu, J Coburn, RJ Collier Proceedings of the National Academy of Sciences 90 (6), 2320-2324, 1993 | 350 | 1993 |
Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism T Hitosugi, J Fan, TW Chung, K Lythgoe, X Wang, J Xie, Q Ge, TL Gu, ... Molecular cell 44 (6), 864-877, 2011 | 349 | 2011 |
Interaction of the protein kinase Raf-1 with 14-3-3 proteins H Fu, K Xia, DC Pallas, C Cui, K Conroy, RP Narsimhan, H Mamon, ... Science 266 (5182), 126-129, 1994 | 341 | 1994 |
Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family GW Reuther, H Fu, LD Cripe, RJ Collier, AM Pendergast Science 266 (5182), 129-133, 1994 | 319 | 1994 |
The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies Z Li, AA Ivanov, R Su, V Gonzalez-Pecchi, Q Qi, S Liu, P Webber, ... Nature communications 8 (1), 14356, 2017 | 282 | 2017 |
Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation EH Goldman, L Chen, H Fu Journal of Biological Chemistry 279 (11), 10442-10449, 2004 | 270 | 2004 |
14-3-3 inhibits Bad-induced cell death through interaction with serine-136 SC Masters, H Yang, SR Datta, ME Greenberg, H Fu Molecular pharmacology 60 (6), 1325-1331, 2001 | 226 | 2001 |
How does arrestin assemble MAPKs into a signaling complex? X Song, S Coffa, H Fu, VV Gurevich Journal of Biological Chemistry 284 (1), 685-695, 2009 | 215 | 2009 |
Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F R Cencic, DR Hall, F Robert, Y Du, J Min, L Li, M Qui, I Lewis, S Kurtkaya, ... Proceedings of the National Academy of Sciences 108 (3), 1046-1051, 2011 | 213 | 2011 |