Blood contains circulating cell free respiratory competent mitochondria ZAA Dache, A Otandault, R Tanos, B Pastor, R Meddeb, C Sanchez, ... Faseb Journal 34 (3), 3616-3630, 2020 | 321 | 2020 |
Metabolic functions of the tumor suppressor p53: Implications in normal physiology, metabolic disorders, and cancer M Lacroix, R Riscal, G Arena, LK Linares, L Le Cam Molecular metabolism 33, 2-22, 2020 | 305 | 2020 |
PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation V Gelmetti, P De Rosa, L Torosantucci, ES Marini, A Romagnoli, ... Autophagy 13 (4), 654-669, 2017 | 305 | 2017 |
The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy S Michiorri, V Gelmetti, E Giarda, F Lombardi, F Romano, R Marongiu, ... Cell Death & Differentiation 17 (6), 962-974, 2010 | 303 | 2010 |
PINK1 protects against cell death induced by mitochondrial depolarization, by phosphorylating Bcl-xL and impairing its pro-apoptotic cleavage G Arena, V Gelmetti, L Torosantucci, D Vignone, G Lamorte, P De Rosa, ... Cell Death & Differentiation 20 (7), 920-930, 2013 | 186 | 2013 |
Chromatin-bound MDM2 regulates serine metabolism and redox homeostasis independently of p53 R Riscal, E Schrepfer, G Arena, MY Cissé, F Bellvert, M Heuillet, ... Molecular cell 62 (6), 890-902, 2016 | 121 | 2016 |
Mitochondrial MDM2 regulates respiratory complex I activity independently of p53 G Arena, MY Cissé, S Pyrdziak, L Chatre, R Riscal, M Fuentes, JJ Arnold, ... Molecular cell 69 (4), 594-609. e8, 2018 | 96 | 2018 |
Resveratrol inhibits Epstein Barr Virus lytic cycle in Burkitt’s lymphoma cells by affecting multiple molecular targets A De Leo, G Arena, E Lacanna, G Oliviero, F Colavita, E Mattia Antiviral research 96 (2), 196-202, 2012 | 84 | 2012 |
PINK1 in the limelight: multiple functions of an eclectic protein in human health and disease G Arena, EM Valente The Journal of pathology 241 (2), 251-263, 2017 | 80 | 2017 |
Molecular pathways in sporadic PD EM Valente, G Arena, L Torosantucci, V Gelmetti Parkinsonism & related disorders 18, S71-S73, 2012 | 64 | 2012 |
Parkinson's disease phenotypes in patient neuronal cultures and brain organoids improved by 2‐Hydroxypropyl‐β‐Cyclodextrin treatment J Jarazo, K Barmpa, J Modamio, C Saraiva, S Sabaté‐Soler, I Rosety, ... Movement Disorders 37 (1), 80-94, 2022 | 56 | 2022 |
AIF meets the CHCHD4/Mia40-dependent mitochondrial import pathway C Reinhardt, G Arena, K Nedara, R Edwards, C Brenner, K Tokatlidis, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (6), 165746, 2020 | 48 | 2020 |
Resveratrol Inhibits Proliferation and Survival of Epstein Barr Virus–Infected Burkitt's Lymphoma Cells Depending on Viral Latency Program A De Leo, G Arena, C Stecca, M Raciti, E Mattia Molecular Cancer Research 9 (10), 1346-1355, 2011 | 48 | 2011 |
Impaired mitochondrial–endoplasmic reticulum interaction and mitophagy in Miro1-mutant neurons in Parkinson’s disease C Berenguer-Escuder, D Grossmann, P Antony, G Arena, K Wasner, ... Human molecular genetics 29 (8), 1353-1364, 2020 | 46 | 2020 |
Inhibition of p38 MAP kinase pathway induces apoptosis and prevents Epstein Barr virus reactivation in Raji cells exposed to lytic cycle inducing compounds G Matusali, G Arena, A De Leo, L Di Renzo, E Mattia Molecular cancer 8, 1-11, 2009 | 44 | 2009 |
Neurodegeneration and neuroinflammation in Parkinson’s disease: a self-sustained loop G Arena, K Sharma, G Agyeah, R Krüger, A Grünewald, JC Fitzgerald Current Neurology and Neuroscience Reports 22 (8), 427-440, 2022 | 43 | 2022 |
Parkin deficiency impairs mitochondrial DNA dynamics and propagates inflammation K Wasner, S Smajic, J Ghelfi, S Delcambre, CA Prada‐Medina, E Knappe, ... Movement Disorders 37 (7), 1405-1415, 2022 | 43 | 2022 |
The Emerging Role of RHOT1/Miro1 in the Pathogenesis of Parkinson's Disease D Grossmann, C Berenguer-Escuder, A Chemla, G Arena, R Krüger Frontiers in neurology 11, 587, 2020 | 42 | 2020 |
AMBRA1 regulates mitophagy by interacting with ATAD3A and promoting PINK1 stability M Di Rienzo, A Romagnoli, F Ciccosanti, G Refolo, V Consalvi, G Arena, ... Autophagy 19, 1-11, 2021 | 41 | 2021 |
Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma MY Cissé, S Pyrdziak, N Firmin, L Gayte, M Heuillet, F Bellvert, M Fuentes, ... Science translational medicine 12 (547), eaay2163, 2020 | 40 | 2020 |