MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer N Valeri, C Braconi, P Gasparini, C Murgia, A Lampis, V Paulus-Hock, ... Cancer cell 25 (4), 469-483, 2014 | 326 | 2014 |
A small molecule RAS-mimetic disrupts RAS association with effector proteins to block signaling SK Athuluri-Divakar, R Vasquez-Del Carpio, K Dutta, SJ Baker, ... Cell 165 (3), 643-655, 2016 | 284 | 2016 |
tsRNA signatures in cancer V Balatti, G Nigita, D Veneziano, A Drusco, GS Stein, TL Messier, ... Proceedings of the National Academy of Sciences 114 (30), 8071-8076, 2017 | 241 | 2017 |
Cancer-derived mutations in the regulatory subunit p85α of phosphoinositide 3-kinase function through the catalytic subunit p110α M Sun, P Hillmann, BT Hofmann, JR Hart, PK Vogt Proceedings of the National Academy of Sciences 107 (35), 15547-15552, 2010 | 188 | 2010 |
Phosphorylation of AKT: a mutational analysis JR Hart, PK Vogt Oncotarget 2 (6), 467, 2011 | 179 | 2011 |
Phosphatidylinositol 3-kinase: the oncoprotein PK Vogt, JR Hart, M Gymnopoulos, H Jiang, S Kang, AG Bader, L Zhao, ... Phosphoinositide 3-kinase in Health and Disease: Volume 2, 79-104, 2011 | 176 | 2011 |
Potent and targeted activation of latent HIV-1 using the CRISPR/dCas9 activator complex SM Saayman, DC Lazar, TA Scott, JR Hart, M Takahashi, JC Burnett, ... Molecular therapy 24 (3), 488-498, 2016 | 155 | 2016 |
Inhibitor of MYC identified in a Kröhnke pyridine library JR Hart, AL Garner, J Yu, Y Ito, M Sun, L Ueno, JK Rhee, MM Baksh, ... Proceedings of the National Academy of Sciences 111 (34), 12556-12561, 2014 | 151 | 2014 |
[Ru (bpy) 2 (L)] Cl2: luminescent metal complexes that bind DNA base mismatches E Rüba, JR Hart, JK Barton Inorganic chemistry 43 (15), 4570-4578, 2004 | 141 | 2004 |
PI3K and STAT3: a new alliance PK Vogt, JR Hart Cancer discovery 1 (6), 481-486, 2011 | 137 | 2011 |
PI 3-kinase and cancer: changing accents PK Vogt, M Gymnopoulos, JR Hart Current opinion in genetics & development 19 (1), 12-17, 2009 | 121 | 2009 |
A rhodium (III) complex for high-affinity DNA base-pair mismatch recognition H Junicke, JR Hart, J Kisko, O Glebov, IR Kirsch, JK Barton Proceedings of the National Academy of Sciences 100 (7), 3737-3742, 2003 | 120 | 2003 |
Quantification of nascent transcription by bromouridine immunocapture nuclear run-on RT-qPCR TC Roberts, JR Hart, MU Kaikkonen, MS Weinberg, PK Vogt, KV Morris Nature protocols 10 (8), 1198-1211, 2015 | 106 | 2015 |
MYC regulates the non-coding transcriptome JR Hart, TC Roberts, MS Weinberg, KV Morris, PK Vogt Oncotarget 5 (24), 12543, 2014 | 94 | 2014 |
The butterfly effect in cancer: a single base mutation can remodel the cell JR Hart, Y Zhang, L Liao, L Ueno, L Du, M Jonkers, JR Yates III, PK Vogt Proceedings of the National Academy of Sciences 112 (4), 1131-1136, 2015 | 81 | 2015 |
Essential role of Stat3 in PI3K-induced oncogenic transformation JR Hart, L Liao, JR Yates III, PK Vogt Proceedings of the National Academy of Sciences 108 (32), 13247-13252, 2011 | 80 | 2011 |
DNA mismatch-specific targeting and hypersensitivity of mismatch-repair-deficient cells to bulky rhodium (III) intercalators JR Hart, O Glebov, RJ Ernst, IR Kirsch, JK Barton Proceedings of the National Academy of Sciences 103 (42), 15359-15363, 2006 | 70 | 2006 |
MYCNOS functions as an antisense RNA regulating MYCN N Vadie, S Saayman, A Lenox, A Ackley, M Clemson, J Burdach, J Hart, ... RNA biology 12 (8), 893-899, 2015 | 55 | 2015 |
Comprehensive RNA-sequencing analysis in serum and muscle reveals novel small RNA signatures with biomarker potential for DMD AML Coenen-Stass, H Sork, S Gatto, C Godfrey, A Bhomra, K Krjutškov, ... Molecular Therapy-Nucleic Acids 13, 1-15, 2018 | 50 | 2018 |
Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K) Y Ito, JR Hart, L Ueno, PK Vogt Proceedings of the National Academy of Sciences 111 (47), 16826-16829, 2014 | 45 | 2014 |