| A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP. 664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies RW Sanders, R Derking, A Cupo, JP Julien, A Yasmeen, N de Val, HJ Kim, ... PLoS pathogens 9 (9), e1003618, 2013 | 1020 | 2013 |
| Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer D Lyumkis, JP Julien, N De Val, A Cupo, CS Potter, PJ Klasse, DR Burton, ... Science 342 (6165), 1484-1490, 2013 | 808 | 2013 |
| Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses JM Jaynes, R Sable, M Ronzetti, W Bautista, Z Knotts, ... Science translational medicine 12 (530), eaax6337, 2020 | 281 | 2020 |
| A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene P Pugach, G Ozorowski, A Cupo, R Ringe, A Yasmeen, N de Val, ... Journal of virology 89 (6), 3380-3395, 2015 | 278 | 2015 |
| Tailored immunogens direct affinity maturation toward HIV neutralizing antibodies B Briney, D Sok, JG Jardine, DW Kulp, P Skog, S Menis, R Jacak, ... Cell 166 (6), 1459-1470. e11, 2016 | 269 | 2016 |
| Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike G Ozorowski, J Pallesen, N de Val, D Lyumkis, CA Cottrell, JL Torres, ... Nature 547 (7663), 360-363, 2017 | 257 | 2017 |
| Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design SK Sharma, N de Val, S Bale, J Guenaga, K Tran, Y Feng, V Dubrovskaya, ... Cell reports 11 (4), 539-550, 2015 | 249 | 2015 |
| Affinity maturation of a potent family of HIV antibodies is primarily focused on accommodating or avoiding glycans F Garces, JH Lee, N de Val, AT de la Pena, L Kong, C Puchades, Y Hua, ... Immunity 43 (6), 1053-1063, 2015 | 225 | 2015 |
| Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles L He, N De Val, CD Morris, N Vora, TC Thinnes, L Kong, P Azadnia, ... Nature communications 7 (1), 12041, 2016 | 191 | 2016 |
| Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding DW Kulp, JM Steichen, M Pauthner, X Hu, T Schiffner, A Liguori, ... Nature communications 8 (1), 1655, 2017 | 155 | 2017 |
| An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability MJ Van Gils, TLGM Van Den Kerkhof, G Ozorowski, CA Cottrell, D Sok, ... Nature microbiology 2 (2), 1-10, 2016 | 151 | 2016 |
| Structures and operating principles of the replisome Y Gao, Y Cui, T Fox, S Lin, H Wang, N de Val, ZH Zhou, W Yang Science 363 (6429), eaav7003, 2019 | 149 | 2019 |
| SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity MG Joyce, WH Chen, RS Sankhala, A Hajduczki, PV Thomas, M Choe, ... Cell reports 37 (12), 2021 | 148 | 2021 |
| Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability L Kong, L He, N De Val, N Vora, CD Morris, P Azadnia, D Sok, B Zhou, ... Nature communications 7 (1), 12040, 2016 | 142 | 2016 |
| Structure-guided redesign increases the propensity of HIV Env to generate highly stable soluble trimers J Guenaga, V Dubrovskaya, N De Val, SK Sharma, B Carrette, AB Ward, ... Journal of virology 90 (6), 2806-2817, 2016 | 137 | 2016 |
| Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like properties J Guenaga, N de Val, K Tran, Y Feng, K Satchwell, AB Ward, RT Wyatt PLoS pathogens 11 (1), e1004570, 2015 | 117 | 2015 |
| A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates MG Joyce, HAD King, I Elakhal-Naouar, A Ahmed, KK Peachman, ... Science translational medicine 14 (632), eabi5735, 2021 | 115 | 2021 |
| Model building and refinement of a natively glycosylated HIV-1 Env protein by high-resolution cryoelectron microscopy JH Lee, N De Val, D Lyumkis, AB Ward Structure 23 (10), 1943-1951, 2015 | 114 | 2015 |
| Structures of Ebola virus GP and sGP in complex with therapeutic antibodies J Pallesen, CD Murin, N De Val, CA Cottrell, KM Hastie, HL Turner, ... Nature microbiology 1 (9), 1-9, 2016 | 110 | 2016 |
| HIV envelope glycoform heterogeneity and localized diversity govern the initiation and maturation of a V2 apex broadly neutralizing antibody lineage E Landais, B Murrell, B Briney, S Murrell, K Rantalainen, ZT Berndsen, ... Immunity 47 (5), 990-1003. e9, 2017 | 100 | 2017 |
Gabriel OzorowskiSr. Laboratory Director, Scripps ResearchEmail verificata su scripps.edu