| Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity Nature Communications 8 (1), DOI: 10.1038/ncomms13958, 2017 | 333* | 2017 |
| The role of a sodium ion binding site in the allosteric modulation of the A2A adenosine G protein-coupled receptor H Gutiérrez-de-Terán, A Massink, D Rodríguez, W Liu, GW Han, ... Structure 21 (12), 2175-2185, 2013 | 142 | 2013 |
| Sodium ion binding pocket mutations and adenosine A2A receptor function A Massink, H Gutiérrez-de-Terán, EB Lenselink, NVO Zacarías, L Xia, ... Molecular pharmacology 87 (2), 305-313, 2015 | 102 | 2015 |
| Binding Kinetics of ZM241385 Derivatives at the Human Adenosine A2A Receptor D Guo, L Xia, JPD van Veldhoven, M Hazeu, T Mocking, J Brussee, ... ChemMedChem 9 (4), 752-761, 2014 | 65 | 2014 |
| Agonists for the Adenosine A1 Receptor with Tunable Residence Time. A Case for Nonribose 4-Amino-6-aryl-5-cyano-2-thiopyrimidines J Louvel, D Guo, M Agliardi, TAM Mocking, R Kars, TP Pham, L Xia, ... Journal of medicinal chemistry 57 (8), 3213-3222, 2014 | 64 | 2014 |
| Scintillation proximity assay (SPA) as a new approach to determine a ligand’s kinetic profile. A case in point for the adenosine A1 receptor L Xia, H de Vries, AP IJzerman, LH Heitman Purinergic Signalling 12, 115-126, 2016 | 53 | 2016 |
| A live cell NanoBRET binding assay allows the study of ligand-binding kinetics to the adenosine A3 receptor M Bouzo-Lorenzo, LA Stoddart, L Xia, AP IJzerman, LH Heitman, ... Purinergic Signalling 15, 139-153, 2019 | 40 | 2019 |
| Structure–Affinity Relationships and Structure–Kinetics Relationships of Pyrido[2,1-f]purine-2,4-dione Derivatives as Human Adenosine A3 Receptor Antagonists L Xia, WAC Burger, JPD van Veldhoven, BJ Kuiper, TT van Duijl, ... Journal of Medicinal Chemistry 60 (17), 7555-7568, 2017 | 33 | 2017 |
| A Binding Kinetics Study of Human Adenosine A3 Receptor Agonists Lizi Xia, Athina Kyrizaki, Dilip K. Tosh, Tirsa T. van Duijl, Jacomina ... Biochemical Pharmacology, In Press, 2018 | 17 | 2018 |
| Kinetics of human Cannabinoid 1 (CB1) receptor antagonists: structure-kinetics relationships (SKRs) and implications for insurmountable antagonism Lizi Xia, Henk de Vries, Xue Yang, Eelke B. Lenselink, Athina Kyrizaki ... Biochemical Pharmacology, 2017 | 17* | 2017 |
| Chemical constituents from Helwingia japonica LZ Xia, M Zhou, YH Xiao, GY Li, XZ Chen, GL Zhang Chin J Nat Med 8 (1), 16-20, 2010 | 17 | 2010 |
| Structure–affinity relationships and structure–kinetic relationships of 1, 2-diarylimidazol-4-carboxamide derivatives as human cannabinoid 1 receptor antagonists L Xia, H de Vries, EB Lenselink, J Louvel, MJ Waring, L Cheng, S Pahlén, ... Journal of Medicinal Chemistry 60 (23), 9545-9564, 2017 | 13 | 2017 |
| Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity. Nat Commun 8: 13958 M Soethoudt, U Grether, J Fingerle, TW Grim, F Fezza, L De Petrocellis, ... | 10 | 2017 |
| ‘N‐Stereogenic Quaternary Ammonium Salts’ from L‐Amino Acids: Synthesis, Separation, and Absolute Configuration HF Wu, WB Lin, LZ Xia, YG Luo, XZ Chen, GY Li, GL Zhang, XF Pan Helvetica Chimica Acta 92 (4), 677-688, 2009 | 9 | 2009 |
| Cellular assay to study β-arrestin recruitment by the cannabinoid receptors 1 and 2 J Bouma, M Soethoudt, N van Gils, L Xia, M van der Stelt, LH Heitman Endocannabinoid Signaling: Methods and Protocols, 189-199, 2022 | 3 | 2022 |
| Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function (vol 87, pg 305, 2015) A Massink, H Gutierrez-de-Teran, EB Lenselink, ON Zacarias, L Xia, ... MOLECULAR PHARMACOLOGY 95 (4), 462-462, 2019 | | 2019 |
| K rizaki LZ Xia Tosh, DK, Dui l, TT an, Roorda,. C., acobson, K..,… Heitman, LH, 248-259, 2018 | | 2018 |
| Applications of Scintillation Proximity Assays (SPA) enabling rapid and sensitive measurement of biochemical assays MDLX Valerie Putmans, Jose Manuel Brea Floriani http://info.perkinelmer.com/Q117-Email-EPKI-SPAWebinarOnDemand-LP …, 2017 | | 2017 |
| Corpora non agunt nisi fixata: ligand receptor binding kinetics in G protein-coupled receptors L Xia Mol Pharmacol 87 (2), 305-13, 2015 | | 2015 |
| Binding kinetics of ZM241385 derivatives at the human adenosine A D Guo, L Xia, JPD Van Veldhoven, M Hazeu, T Mocking, J Brussee, ... Drug-target residence time: a case for the adenosine A1 and A2A receptors, 109, 2014 | | 2014 |
