| In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development KLR Brouwer, D Keppler, KA Hoffmaster, DAJ Bow, Y Cheng, Y Lai, ... Clinical Pharmacology & Therapeutics 94 (1), 95-112, 2013 | 285 | 2013 |
| Coproporphyrins in plasma and urine can be appropriate clinical biomarkers to recapitulate drug-drug interactions mediated by organic anion transporting polypeptide inhibition Y Lai, S Mandlekar, H Shen, VK Holenarsipur, R Langish, P Rajanna, ... Journal of Pharmacology and Experimental Therapeutics 358 (3), 397-404, 2016 | 163 | 2016 |
| Coproporphyrins I and III as functional markers of OATP1B activity: in vitro and in vivo evaluation in preclinical species H Shen, J Dai, T Liu, Y Cheng, W Chen, C Freeden, Y Zhang, ... Journal of Pharmacology and Experimental Therapeutics 357 (2), 382-393, 2016 | 110 | 2016 |
| Expression of organic anion transporter 2 in the human kidney and its potential role in the tubular secretion of guanine-containing antiviral drugs Y Cheng, A Vapurcuyan, M Shahidullah, LM Aleksunes, RM Pelis Drug Metabolism and Disposition 40 (3), 617-624, 2012 | 94 | 2012 |
| Small molecule splicing modifiers with systemic HTT-lowering activity A Bhattacharyya, CR Trotta, J Narasimhan, KJ Wiedinger, W Li, ... Nature communications 12 (1), 7299, 2021 | 58 | 2021 |
| In vitro model systems to investigate bile salt export pump (BSEP) activity and drug interactions: a review Y Cheng, TF Woolf, J Gan, K He Chemico-biological interactions 255, 23-30, 2016 | 44 | 2016 |
| Characterization of the disposition and toxicokinetics of N-butylpyridinium chloride in male F-344 rats and female B6C3F1 mice and its transport by organic cation transporter 2 Y Cheng, SH Wright, MJ Hooth, IG Sipes Drug metabolism and disposition 37 (4), 909-916, 2009 | 27 | 2009 |
| Involvement of drug transporters in organ toxicity: the fundamental basis of drug discovery and development Y Cheng, A El-Kattan, Y Zhang, AS Ray, Y Lai Chemical research in toxicology 29 (4), 545-563, 2016 | 25 | 2016 |
| Biliary excretion of pravastatin and taurocholate in rats with bile salt export pump (Bsep) impairment Y Cheng, C Freeden, Y Zhang, P Abraham, H Shen, D Wescott, ... Biopharmaceutics & Drug Disposition 37 (5), 276-286, 2016 | 22 | 2016 |
| Functional significance of conserved cysteines in the human organic cation transporter 2 RM Pelis, Y Dangprapai, Y Cheng, X Zhang, J Terpstra, SH Wright American Journal of Physiology-Renal Physiology 303 (2), F313-F320, 2012 | 19 | 2012 |
| International Transporter C (2013) In vitro methods to support transporter evaluation in drug discovery and development KL Brouwer, D Keppler, KA Hoffmaster, DA Bow, Y Cheng, Y Lai, JE Palm, ... Clin Pharmacol Ther 94 (1), 95-112, 0 | 19 | |
| Characterization of the inhibitory effects of N-butylpyridinium chloride and structurally related ionic liquids on organic cation transporters 1/2 and human toxic extrusion … Y Cheng, LJ Martinez-Guerrero, SH Wright, RK Kuester, MJ Hooth, ... Drug metabolism and disposition 39 (9), 1755-1761, 2011 | 14 | 2011 |
| Effects of dose and route on the disposition and kinetics of 1-butyl-1-methylpyrrolidinium chloride in male F-344 rats GA Knudsen, Y Cheng, RK Kuester, MJ Hooth, IG Sipes Drug metabolism and disposition 37 (11), 2171-2177, 2009 | 14 | 2009 |
| Effect of Spatholobus suberectus on the bone marrow cells and related cytokines of mice DH Chen, X Luo, MY Yu, YQ Zhao, YF Cheng, ZR Yang Zhongguo Zhong yao za zhi= Zhongguo Zhongyao Zazhi= China Journal of Chinese …, 2004 | 12 | 2004 |
| Clinical significance of CYP2C19 polymorphisms on the metabolism and pharmacokinetics of 11β‐hydroxysteroid dehydrogenase type‐1 inhibitor BMS‐823778 Y Cheng, L Wang, L Iacono, D Zhang, W Chen, J Gong, WG Humphreys, ... British Journal of Clinical Pharmacology 84 (1), 130-141, 2018 | 10 | 2018 |
| Bile salt homeostasis in normal and Bsep gene knockout rats with single and repeated doses of troglitazone Y Cheng, S Chen, C Freeden, W Chen, Y Zhang, P Abraham, DM Nelson, ... Journal of Pharmacology and Experimental Therapeutics 362 (3), 385-394, 2017 | 9 | 2017 |
| The influence of Bazhen decoction on hematopoietic modulator in anaemic mice Z Chun, X Luo, D Chen, M Yu, Y Cheng, Z Yang Sheng wu yi xue Gong Cheng xue za zhi= Journal of Biomedical Engineering …, 2004 | 9 | 2004 |
| Application of a PBPK model to elucidate the changes of systemic and liver exposures for rosuvastatin, carotegrast, and bromfenac followed by OATP inhibition in monkeys Y Cheng, X Liang, J Hao, C Niu, Y Lai Clinical and Translational Science 14 (5), 1924-1934, 2021 | 6 | 2021 |
| Application of static models to predict midazolam clinical interactions in the presence of single or multiple hepatitis C virus drugs Y Cheng, L Ma, SY Chang, WG Humphreys, W Li Drug Metabolism and Disposition 44 (8), 1372-1380, 2016 | 6 | 2016 |
| Novel rna transcript A Bhattacharyya, Y Cheng, KA Effenberger, W Li, J Narasimhan, ... US Patent App. 17/524,586, 2022 | | 2022 |
Yurong Lai, PhD FAAPSGilead Scienses IncEmail verificata su gilead.com
