Bioinformatic analysis of a PLP-dependent enzyme superfamily suitable for biocatalytic applications F Steffen-Munsberg, C Vickers, H Kohls, H Land, H Mallin, A Nobili, ... Biotechnology advances 33 (5), 566-604, 2015 | 258 | 2015 |
Drug design for ever, from hype to hope G Seddon, V Lounnas, R McGuire, T Van Den Bergh, RP Bywater, ... Journal of computer-aided molecular design 26, 137-150, 2012 | 73 | 2012 |
Engineering the Amine Transaminase from Vibrio fluvialis towards Branched‐Chain Substrates M Genz, O Melse, S Schmidt, C Vickers, M Dörr, T Van Den Bergh, ... ChemCatChem 8 (20), 3199-3202, 2016 | 62 | 2016 |
Switch in cofactor specificity of a Baeyer–Villiger monooxygenase A Beier, S Bordewick, M Genz, S Schmidt, T Van Den Bergh, C Peters, ... ChemBioChem 17 (24), 2312-2315, 2016 | 61 | 2016 |
A structural classification of carbohydrate epimerases: from mechanistic insights to practical applications S Van Overtveldt, T Verhaeghe, HJ Joosten, T van den Bergh, K Beerens, ... Biotechnology Advances 33 (8), 1814-1828, 2015 | 53 | 2015 |
Alteration of the Donor/Acceptor Spectrum of the (S)-Amine Transaminase from Vibrio fluvialis M Genz, C Vickers, T Van den Bergh, HJ Joosten, M Dörr, M Höhne, ... International journal of molecular sciences 16 (11), 26953-26963, 2015 | 48 | 2015 |
Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily E Lanfranchi, T Pavkov-Keller, EM Koehler, M Diepold, K Steiner, ... Scientific Reports 7 (1), 46738, 2017 | 34 | 2017 |
Simultaneous use of in silico design and a correlated mutation network as a tool to efficiently guide enzyme engineering A Nobili, Y Tao, IV Pavlidis, T van den Bergh, HJ Joosten, T Tan, ... ChemBioChem 16 (5), 805-810, 2015 | 30 | 2015 |
Novel tools for extraction and validation of disease‐related mutations applied to fabry disease R Kuipers, T van den Bergh, HJ Joosten, RH Lekanne dit Deprez, ... Human mutation 31 (9), 1026-1032, 2010 | 30 | 2010 |
Going to extremes–a metagenomic journey into the dark matter of life A Aevarsson, AK Kaczorowska, BT Adalsteinsson, J Ahlqvist, ... FEMS microbiology letters 368 (12), fnab067, 2021 | 27 | 2021 |
Biocatalytic synthesis of α-amino ketones SW Chun, ARH Narayan Synlett 30 (11), 1269-1274, 2019 | 22 | 2019 |
CorNet: Assigning function to networks of co-evolving residues by automated literature mining T Van Den Bergh, G Tamo, A Nobili, Y Tao, T Tan, UT Bornscheuer, ... PLoS One 12 (5), e0176427, 2017 | 12 | 2017 |
Bioinformatic analysis of fold-type III PLP-dependent enzymes discovers multimeric racemases AM Knight, A Nobili, T van den Bergh, M Genz, HJ Joosten, D Albrecht, ... Applied microbiology and biotechnology 101, 1499-1507, 2017 | 8 | 2017 |
Mind the gap: preventing circularity in missense variant prediction S Heijl, B Vroling, T van den Bergh, HJ Joosten Biorxiv, 2020.05. 06.080424, 2020 | 4 | 2020 |
AmiP from hyperthermophilic Thermus parvatiensis prophage is a thermoactive and ultrathermostable peptidoglycan lytic amidase A Jasilionis, M Plotka, L Wang, S Dorawa, J Lange, H Watzlawick, ... Protein Science 32 (3), e4585, 2023 | 1 | 2023 |
Erratum: Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily E Lanfranchi, T Pavkov-Keller, EM Koehler, M Diepold, K Steiner, ... Scientific Reports 7, 2017 | 1 | 2017 |
Transforming protein engineering: advanced integration of deep learning and 3DM technology for superior protein function predictions HJ Joosten, B Vroling, S Heijl, T van den Bergh | | 2023 |
Towards a better understanding of proteins through protein-family data integration T van den Bergh PQDT-Global, 2022 | | 2022 |
Common pitfalls and novel opportunities for predicting variant pathogenicity T van den Bergh, B Vroling, RKP Kuipers, HJ Joosten, G Vriend protein-family data integration., 57, 2016 | | 2016 |
Inherited arrhythmia syndromes, how to identify pathogenic mutations? B Vroling, T van den Bergh, M Alders, S Heijl, M Tanck, RLD Deprez, ... protein-family data integration., 95, 0 | | |