| Injection of cultured cells with a ROCK inhibitor for bullous keratopathy S Kinoshita, N Koizumi, M Ueno, N Okumura, K Imai, H Tanaka, ... New England Journal of Medicine 378 (11), 995-1003, 2018 | 472 | 2018 |
| Enhancement on primate corneal endothelial cell survival in vitro by a ROCK inhibitor N Okumura, M Ueno, N Koizumi, Y Sakamoto, K Hirata, J Hamuro, ... Investigative ophthalmology & visual science 50 (8), 3680-3687, 2009 | 324 | 2009 |
| ROCK inhibitor converts corneal endothelial cells into a phenotype capable of regenerating in vivo endothelial tissue N Okumura, N Koizumi, M Ueno, Y Sakamoto, H Takahashi, H Tsuchiya, ... The American journal of pathology 181 (1), 268-277, 2012 | 283 | 2012 |
| Cultivated corneal endothelial cell sheet transplantation in a primate model N Koizumi, Y Sakamoto, N Okumura, N Okahara, H Tsuchiya, R Torii, ... Investigative ophthalmology & visual science 48 (10), 4519-4526, 2007 | 266 | 2007 |
| The ROCK inhibitor eye drop accelerates corneal endothelium wound healing N Okumura, N Koizumi, EDP Kay, M Ueno, Y Sakamoto, S Nakamura, ... Investigative ophthalmology & visual science 54 (4), 2493-2502, 2013 | 259 | 2013 |
| Derivation of mesenchymal stromal cells from pluripotent stem cells through a neural crest lineage using small molecule compounds with defined media M Fukuta, Y Nakai, K Kirino, M Nakagawa, K Sekiguchi, S Nagata, ... PloS one 9 (12), e112291, 2014 | 193 | 2014 |
| Enhancement of corneal endothelium wound healing by Rho-associated kinase (ROCK) inhibitor eye drops N Okumura, N Koizumi, M Ueno, Y Sakamoto, H Takahashi, K Hirata, ... British Journal of Ophthalmology 95 (7), 1006-1009, 2011 | 189 | 2011 |
| Rho kinase inhibitor enables cell-based therapy for corneal endothelial dysfunction N Okumura, Y Sakamoto, K Fujii, J Kitano, S Nakano, Y Tsujimoto, ... Scientific reports 6 (1), 26113, 2016 | 182 | 2016 |
| Inhibition of TGF-β signaling enables human corneal endothelial cell expansion in vitro for use in regenerative medicine N Okumura, EDP Kay, M Nakahara, J Hamuro, S Kinoshita, N Koizumi PloS one 8 (2), e58000, 2013 | 180 | 2013 |
| Rho-associated kinase inhibitor eye drop treatment as a possible medical treatment for Fuchs corneal dystrophy N Koizumi, N Okumura, M Ueno, H Nakagawa, J Hamuro, S Kinoshita Cornea 32 (8), 1167-1170, 2013 | 158 | 2013 |
| Development of new therapeutic modalities for corneal endothelial disease focused on the proliferation of corneal endothelial cells using animal models N Koizumi, N Okumura, S Kinoshita Experimental eye research 95 (1), 60-67, 2012 | 156 | 2012 |
| Effect of the rho-associated kinase inhibitor eye drop (Ripasudil) on corneal endothelial wound healing N Okumura, Y Okazaki, R Inoue, K Kakutani, S Nakano, S Kinoshita, ... Investigative ophthalmology & visual science 57 (3), 1284-1292, 2016 | 139 | 2016 |
| Involvement of cyclin D and p27 in cell proliferation mediated by ROCK inhibitors Y-27632 and Y-39983 during corneal endothelium wound healing N Okumura, S Nakano, EDP Kay, R Numata, A Ota, Y Sowa, T Sakai, ... Investigative ophthalmology & visual science 55 (1), 318-329, 2014 | 125 | 2014 |
| Five-year follow-up of first 11 patients undergoing injection of cultured corneal endothelial cells for corneal endothelial failure K Numa, K Imai, M Ueno, K Kitazawa, H Tanaka, JD Bush, S Teramukai, ... Ophthalmology 128 (4), 504-514, 2021 | 120 | 2021 |
| New therapeutic modality for corneal endothelial disease using Rho-associated kinase inhibitor eye drops N Koizumi, N Okumura, M Ueno, S Kinoshita Cornea 33, S25-S31, 2014 | 119 | 2014 |
| Corneal endothelial expansion promoted by human bone marrow mesenchymal stem cell-derived conditioned medium M Nakahara, N Okumura, EDP Kay, M Hagiya, K Imagawa, Y Hosoda, ... PloS one 8 (7), e69009, 2013 | 119 | 2013 |
| Application of Rho kinase inhibitors for the treatment of corneal endothelial diseases N Okumura, S Kinoshita, N Koizumi Journal of ophthalmology 2017 (1), 2646904, 2017 | 114 | 2017 |
| Cell-based approach for treatment of corneal endothelial dysfunction N Okumura, S Kinoshita, N Koizumi Cornea 33, S37-S41, 2014 | 108 | 2014 |
| Effect of the Rho kinase inhibitor Y-27632 on corneal endothelial wound healing N Okumura, R Inoue, Y Okazaki, S Nakano, H Nakagawa, S Kinoshita, ... Investigative ophthalmology & visual science 56 (10), 6067-6074, 2015 | 103 | 2015 |
| Cultivated corneal endothelial transplantation in a primate: possible future clinical application in corneal endothelial regenerative medicine N Koizumi, Y Sakamoto, N Okumura, H Tsuchiya, R Torii, LJ Cooper, ... Cornea 27, S48-S55, 2008 | 103 | 2008 |