| The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription R Santoro, J Li, I Grummt Nature genetics 32 (3), 393-396, 2002 | 508 | 2002 |
| Intergenic transcripts regulate the epigenetic state of rRNA genes C Mayer, KM Schmitz, J Li, I Grummt, R Santoro Molecular cell 22 (3), 351-361, 2006 | 392 | 2006 |
| NoRC—a novel member of mammalian ISWI‐containing chromatin remodeling machines R Strohner, A Nemeth, P Jansa, U Hofmann‐Rohrer, R Santoro, G Längst, ... The EMBO journal, 2001 | 389 | 2001 |
| The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors D Zingg, J Debbache, SM Schaefer, E Tuncer, SC Frommel, P Cheng, ... Nature communications 6 (1), 6051, 2015 | 347 | 2015 |
| The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription Y Zhou, R Santoro, I Grummt The EMBO journal 21 (17), 4632-4640, 2002 | 307 | 2002 |
| Molecular mechanisms mediating methylation-dependent silencing of ribosomal gene transcription R Santoro, I Grummt Molecular cell 8 (3), 719-725, 2001 | 301 | 2001 |
| The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats C Guetg, P Lienemann, V Sirri, I Grummt, D Hernandez‐Verdun, ... The EMBO journal 29 (13), 2135-2146, 2010 | 228 | 2010 |
| Epigenetic mechanism of rRNA gene silencing: temporal order of NoRC-mediated histone modification, chromatin remodeling, and DNA methylation R Santoro, I Grummt Molecular and cellular biology 25 (7), 2539-2546, 2005 | 218 | 2005 |
| Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA C Guetg, F Scheifele, F Rosenthal, MO Hottiger, R Santoro Molecular cell 45 (6), 790-800, 2012 | 176 | 2012 |
| Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells J Espada, E Ballestar, R Santoro, MF Fraga, A Villar-Garea, A Nemeth, ... Nucleic acids research 35 (7), 2191-2198, 2007 | 175 | 2007 |
| DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells SB Bachmann, SC Frommel, R Camicia, HC Winkler, R Santoro, ... Molecular cancer 13, 1-24, 2014 | 164 | 2014 |
| Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-κB target genes S Erener, V Pétrilli, I Kassner, R Minotti, R Castillo, R Santoro, PO Hassa, ... Molecular cell 46 (2), 200-211, 2012 | 159 | 2012 |
| lncRNA maturation to initiate heterochromatin formation in the nucleolus is required for exit from pluripotency in ESCs N Savić, D Bär, S Leone, SC Frommel, FA Weber, E Vollenweider, ... Cell stem cell 15 (6), 720-734, 2014 | 154 | 2014 |
| BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence L Gu, SC Frommel, CC Oakes, R Simon, K Grupp, CY Gerig, D Bär, ... Nature genetics 47 (1), 22-30, 2015 | 149 | 2015 |
| Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans R Santoro, KM Schmitz, J Sandoval, I Grummt EMBO reports 11 (1), 52-58, 2010 | 144 | 2010 |
| The chromatin remodeling complex NoRC controls replication timing of rRNA genes J Li, R Santoro, K Koberna, I Grummt The EMBO journal 24 (1), 120-127, 2005 | 139 | 2005 |
| EZH2-mediated primary cilium deconstruction drives metastatic melanoma formation D Zingg, J Debbache, R Peña-Hernández, AT Antunes, SM Schaefer, ... Cancer cell 34 (1), 69-84. e14, 2018 | 124 | 2018 |
| Genome organization in and around the nucleolus C Bersaglieri, R Santoro Cells 8 (6), 579, 2019 | 118 | 2019 |
| Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma PF Cheng, O Shakhova, DS Widmer, OM Eichhoff, D Zingg, SC Frommel, ... Genome biology 16, 1-16, 2015 | 113 | 2015 |
| Formation of nuclear heterochromatin: the nucleolar point of view C Guetg, R Santoro Epigenetics 7 (8), 811-814, 2012 | 108 | 2012 |
