| Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function IK Zervantonakis, SK Hughes-Alford, JL Charest, JS Condeelis, FB Gertler, ... Proceedings of the National Academy of Sciences 109 (34), 13515-13520, 2012 | 1000 | 2012 |
| The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 441 | 2020 |
| Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer ET Roussos, M Balsamo, SK Alford, JB Wyckoff, B Gligorijevic, Y Wang, ... Journal of cell science 124 (13), 2120-2131, 2011 | 227 | 2011 |
| 2D protrusion but not motility predicts growth factor–induced cancer cell migration in 3D collagen AS Meyer, SK Hughes-Alford, JE Kay, A Castillo, A Wells, FB Gertler, ... Journal of Cell Biology 197 (6), 721-729, 2012 | 135 | 2012 |
| Mena binds α5 integrin directly and modulates α5β1 function SL Gupton, D Riquelme, SK Hughes-Alford, J Tadros, SS Rudina, ... Journal of Cell Biology 198 (4), 657-676, 2012 | 77 | 2012 |
| Endothelial cell migration on RGD-peptide-containing PEG hydrogels in the presence of sphingosine 1-phosphate BK Wacker, SK Alford, EA Scott, MD Thakur, GD Longmore, DL Elbert Biophysical journal 94 (1), 273-285, 2008 | 73 | 2008 |
| Delivery of sphingosine 1-phosphate from poly (ethylene glycol) hydrogels BK Wacker, EA Scott, MM Kaneda, SK Alford, DL Elbert Biomacromolecules 7 (4), 1335-1343, 2006 | 58 | 2006 |
| RAS mutations affect tumor necrosis factor–induced apoptosis in colon carcinoma cells via ERK-modulatory negative and positive feedback circuits along with non-ERK pathway effects PK Kreeger, R Mandhana, SK Alford, KM Haigis, DA Lauffenburger Cancer research 69 (20), 8191-8199, 2009 | 54 | 2009 |
| The making of a PreCancer Atlas: promises, challenges, and opportunities S Srivastava, S Ghosh, J Kagan, R Mazurchuk, E Boja, R Chuaqui, ... Trends in Cancer 4 (8), 523-536, 2018 | 49 | 2018 |
| PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena SK Hughes, MJ Oudin, J Tadros, J Neil, A Del Rosario, BA Joughin, ... Molecular biology of the cell 26 (21), 3867-3878, 2015 | 44 | 2015 |
| α-Actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation Y Feng, H Ngu, SK Alford, M Ward, F Yin, GD Longmore Experimental cell research 319 (8), 1124-1135, 2013 | 41 | 2013 |
| CD46-induced immunomodulatory CD4+ T cells express the adhesion molecule and chemokine receptor pattern of intestinal T cells SK Alford, GD Longmore, WF Stenson, C Kemper The Journal of Immunology 181 (4), 2544-2555, 2008 | 39 | 2008 |
| Characterization of the expression of the pro-metastatic MenaINV isoform during breast tumor progression MJ Oudin, SK Hughes, N Rohani, MN Moufarrej, JG Jones, JS Condeelis, ... Clinical & experimental metastasis 33, 249-261, 2016 | 33 | 2016 |
| Quantitative analysis of gradient sensing: towards building predictive models of chemotaxis in cancer SK Hughes-Alford, DA Lauffenburger Current opinion in cell biology 24 (2), 284-291, 2012 | 33 | 2012 |
| Signaling network state predicts twist-mediated effects on breast cell migration across diverse growth factor contexts HD Kim, AS Meyer, JP Wagner, SK Alford, A Wells, FB Gertler, ... Molecular & Cellular Proteomics 10 (11), 2011 | 33 | 2011 |
| Fluid shear stress modulates cell migration induced by sphingosine 1-phosphate and vascular endothelial growth factor SK Hughes, BK Wacker, MM Kaneda, DL Elbert Annals of biomedical engineering 33, 1003-1014, 2005 | 32 | 2005 |
| Systems approaches to cancer biology TC Archer, EJ Fertig, SJC Gosline, M Hafner, SK Hughes, BA Joughin, ... Cancer research 76 (23), 6774-6777, 2016 | 30 | 2016 |
| MenaINV mediates synergistic cross-talk between signaling pathways driving chemotaxis and haptotaxis MJ Oudin, MA Miller, JAZ Klazen, T Kosciuk, A Lussiez, SK Hughes, ... Molecular Biology of the Cell 27 (20), 3085-3094, 2016 | 22 | 2016 |
| Precancer Atlas: present and future S Srivastava, PD Wagner, SK Hughes, S Ghosh Cancer Prevention Research 16 (7), 379-384, 2023 | 13 | 2023 |
| Endothelial cell migration in human plasma is enhanced by a narrow range of added sphingosine 1‐phosphate: Implications for biomaterials design SK Alford, MM Kaneda, BK Wacker, DL Elbert Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2009 | 12 | 2009 |