| From snake venom toxins to therapeutics–Cardiovascular examples CY Koh, RM Kini Toxicon 59 (4), 497-506, 2012 | 270 | 2012 |
| Metalloproteases Affecting Blood Coagulation, Fibrinolysis and Platelet Aggregation from Snake Venoms: Definition and Nomenclature of Interaction Sites RM Kini, CY Koh Toxins 8 (10), 284, 2016 | 177 | 2016 |
| Molecular diversity of anticoagulants from haematophagous animals CY Koh, RM Kini Thrombosis and haemostasis 102 (09), 437-453, 2009 | 126 | 2009 |
| Variegin, a novel fast and tight binding thrombin inhibitor from the tropical bont tick CY Koh, M Kazimirova, A Trimnell, P Takac, M Labuda, PA Nuttall, ... Journal of Biological Chemistry 282 (40), 29101-29113, 2007 | 125 | 2007 |
| Distinct states of methionyl-tRNA synthetase indicate inhibitor binding by conformational selection CY Koh, JE Kim, S Shibata, RM Ranade, M Yu, J Liu, JR Gillespie, ... Structure 20 (10), 1681-1691, 2012 | 73 | 2012 |
| Urea-based inhibitors of Trypanosoma brucei methionyl-tRNA synthetase: selectivity and in vivo characterization S Shibata, JR Gillespie, RM Ranade, CY Koh, JE Kim, JU Laydbak, ... Journal of Medicinal Chemistry 55 (14), 6342-6351, 2012 | 65 | 2012 |
| Snake venom three-finger toxins and their potential in drug development targeting cardiovascular diseases RM Kini, CY Koh Biochemical Pharmacology 181, 114105, 2020 | 50 | 2020 |
| Crystal structure of thrombin in complex with S-variegin: insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors CY Koh, S Kumar, M Kazimirova, PA Nuttall, UP Radhakrishnan, S Kim, ... PloS one 6 (10), e26367, 2011 | 48 | 2011 |
| Omics technologies for profiling toxin diversity and evolution in snake venom: impacts on the discovery of therapeutic and diagnostic agents CM Modahl, RK Brahma, CY Koh, N Shioi, RM Kini Annual Review of Animal Biosciences 8 (1), 91-116, 2020 | 42 | 2020 |
| Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness CY Koh, JE Kim, AB Wetzel, WJ de van der Schueren, S Shibata, ... PLoS neglected tropical diseases 8 (4), e2775, 2014 | 41 | 2014 |
| Anticoagulants from hematophagous animals. CY Koh, RM Kini Expert review of hematology 1 (2), 135, 2008 | 38 | 2008 |
| The Procoagulant Snake Venom Serine Protease Potentially Having a Dual, Blood Coagulation Factor V and X-Activating Activity Z Latinović, A Leonardi, CY Koh, RM Kini, A Trampuš Bakija, J Pungerčar, ... Toxins 12 (6), 358, 2020 | 37 | 2020 |
| Identification of Potent Inhibitors of the Trypanosoma brucei Methionyl-tRNA Synthetase via High-Throughput Orthogonal Screening L Pedró-Rosa, FS Buckner, RM Ranade, C Eberhart, F Madoux, ... Journal of biomolecular screening 20 (1), 122-130, 2015 | 37 | 2015 |
| 5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors Z Zhang, CY Koh, RM Ranade, S Shibata, JR Gillespie, MA Hulverson, ... ACS Infectious Diseases 2 (6), 399-404, 2016 | 32 | 2016 |
| Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors W Huang, Z Zhang, X Barros-Álvarez, CY Koh, RM Ranade, JR Gillespie, ... European Journal of Medicinal Chemistry 124, 1081-1092, 2016 | 30 | 2016 |
| Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design CY Koh, JE Kim, AJ Napoli, CLMJ Verlinde, E Fan, FS Buckner, ... Molecular and biochemical parasitology 189 (1-2), 26-32, 2013 | 30 | 2013 |
| Toxins are an excellent source of therapeutic agents against cardiovascular diseases CY Koh, CM Modahl, N Kulkarni, RM Kini Seminars in thrombosis and hemostasis 44 (07), 691-706, 2018 | 29 | 2018 |
| A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens CY Koh, L Kallur Siddaramaiah, RM Ranade, J Nguyen, T Jian, Z Zhang, ... Acta Crystallographica Section D: Biological Crystallography 71 (8), 1684-1698, 2015 | 26 | 2015 |
| X-ray crystallographic analysis of time-dependent binding of guanidine hydrochloride to HEWL: First steps during protein unfolding T Raskar, CY Koh, S Niebling, RM Kini, MV Hosur International journal of biological macromolecules 122, 903-913, 2019 | 22 | 2019 |
| Avathrin: a novel thrombin inhibitor derived from a multicopy precursor in the salivary glands of the ixodid tick, Amblyomma variegatum JK Iyer, CY Koh, M Kazimirova, L Roller, C Jobichen, K Swaminathan, ... The FASEB Journal 31 (7), 2981-2995, 2017 | 19 | 2017 |
Manjunatha KiniProfessor of Biological Sciences, National University of SingaporeEmail verificata su nus.edu.sg