Stress-induced low complexity RNA activates physiological amyloidogenesis M Wang, X Tao, MD Jacob, CA Bennett, JJD Ho, ML Gonzalgo, TE Audas, ... Cell reports 24 (7), 1713-1721. e4, 2018 | 99 | 2018 |
Tristetraprolin recruits eukaryotic initiation factor 4E2 to repress translation of AU-rich element-containing mRNAs X Tao, G Gao Molecular and cellular biology 35 (22), 3921-3932, 2015 | 67 | 2015 |
Nmnat restores neuronal integrity by neutralizing mutant Huntingtin aggregate-induced progressive toxicity Y Zhu, C Li, X Tao, JM Brazill, J Park, Z Diaz-Perez, RG Zhai Proceedings of the National Academy of Sciences 116 (38), 19165-19175, 2019 | 37 | 2019 |
NMNAT promotes glioma growth through regulating post-translational modifications of P53 to inhibit apoptosis J Liu, X Tao, Y Zhu, C Li, K Ruan, Z Diaz-Perez, P Rai, H Wang, RG Zhai Elife 10, e70046, 2021 | 23 | 2021 |
Sorbitol reduction via govorestat ameliorates synaptic dysfunction and neurodegeneration in sorbitol dehydrogenase deficiency Y Zhu, AG Lobato, AP Rebelo, T Canic, N Ortiz-Vega, X Tao, S Syed, ... JCI insight 8 (10), e164954, 2023 | 21 | 2023 |
Phenylbutyrate modulates polyamine acetylase and ameliorates Snyder-Robinson syndrome in a Drosophila model and patient cells X Tao, Y Zhu, Z Diaz-Perez, SH Yu, JR Foley, TM Stewart, RA Casero Jr, ... JCI insight 7 (13), e158457, 2022 | 14 | 2022 |
Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder–Robinson syndrome TM Stewart, JR Foley, CE Holbert, M Khomutov, N Rastkari, X Tao, ... EMBO Molecular Medicine 15 (11), e17833, 2023 | 12 | 2023 |
Development of a Redox-Sensitive Spermine Prodrug for the Potential Treatment of Snyder Robinson Syndrome MP Tantak, V Sekhar, X Tao, RG Zhai, O Phanstiel IV Journal of Medicinal Chemistry 64 (21), 15593–15607, 2021 | 11 | 2021 |
Loss of Fic causes progressive neurodegeneration in a Drosophila model of hereditary spastic paraplegia AG Lobato, N Ortiz-Vega, T Canic, X Tao, N Bucan, K Ruan, AP Rebelo, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1870 (7), 167348, 2024 | 3 | 2024 |
Reduction of spermine synthase enhances autophagy to suppress Tau accumulation X Tao, J Liu, Z Diaz-Perez, JR Foley, A Nwafor, TM Stewart, RA Casero Jr, ... Cell Death & Disease 15 (5), 333, 2024 | 3 | 2024 |
MicroRNA miR-1002 enhances NMNAT-mediated stress response by modulating alternative splicing J Park, Y Zhu, X Tao, JM Brazill, C Li, S Wuchty, RG Zhai Iscience 19, 1048-1064, 2019 | 2 | 2019 |
Development and characterization of a Drosophila model of Snyder-Robinson syndrome X Tao, RG Zhai Academic Press, 2025 | | 2025 |
Method of treating polyamine imbalance-related disorders RG Zhai, X Tao, C Li, Y Zhu, Z Diaz-Perez US Patent App. 18/039,897, 2024 | | 2024 |
Knight in Splicing Armor: Alternative Splicing as a Neuroprotective Mechanism J Park, X Tao, RG Zhai OBM Genetics 4 (1), doi:10.21926/obm.genet.2001106, 2020 | | 2020 |